Results 151 to 160 of about 1,735,150 (286)

Virologic Failure [PDF]

, 2020
openaire   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Absence of progressive liver disease after treatment in children with chronic hepatitis C: A nationwide registry study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives In adults with chronic hepatitis C (CHC) and advanced fibrosis, hepatocellular carcinoma (HCC) surveillance is recommended after achieving a sustained virologic response (SVR). However, post‐SVR surveillance strategies for children remain unclear. The aim of this study was to assess the durability of SVR and determine an appropriate
Hitoshi Tajiri, Mitsuyoshi Suzuki, Yuri Etani, Yoshinori Ito, Koichi Ito, Tomoya Fukuoka, Tatsuki Mizuochi   +6 more
wiley   +1 more source

Factors associated with virological failure by 30 months of ART.

, 2015
*CD4+ T cells count in cells/mm3;**HIV RNA level: copies/mlFactors associated with virological failure by 30 months of ART.
Uwe Gerd Liebert (819928), Melanie Maier (427543), Andargachew Mulu (819927)   +2 more
core   +1 more source

Impact of Cardiometabolic Risk Factors and Steatotic Liver Disease on Liver‐Related Outcomes in Patients With Chronic Hepatitis C After Curative Antiviral Therapy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Patients with chronic hepatitis C (CHC) frequently present with steatotic liver disease (SLD) and cardiometabolic risk factors (CMRFs). This study aimed to evaluate the impact of SLD and CMRFs on liver‐related outcomes (LROs) in CHC patients after HCV eradication.
Chung‐Feng Huang, Yi‐Hung Lin, Pei‐Chien Tsai, Ming‐Lun Yeh, Chih‐Wen Wang, Tyng‐Yuan Jang, Po‐Cheng Liang, Yu‐Ju Wei, Nai‐Jen Hou, Ming‐Yen Hsieh, Chao‐Kuan Huang, Tzu‐Chun Lin, Jee‐Fu Huang, Chia‐Yen Dai, Wan‐Long Chuang, Ming‐Lung Yu   +15 more
wiley   +1 more source

Factors associated with baseline virological failure (>5,000 copies/ml).

, 2015
ART, antiretroviral therapy; BMI, body mass index; CI, confidence interval; RR, risk ratio; WHO, World Health Organization.Factors associated with baseline virological failure (>5,000 copies/ml).
William C. Miller (223257), Sundeep Gupta (727893), Alice Soko (727887), Ronald Mataya (727895), Irving Hoffman (243727), Sarah E. Rutstein (727886), Deborah Kamwendo (34032), Stephanie B. Wheeler (727891), Mina C. Hosseinipour (143744), Memory Mkandawire (727888), Reuben Mwenda (727894), Frank Chimbwandira (244095), Andrea K. Biddle (727889), Morris Weinberger (727890), Steve Kamiza (377534), Abdoulaye Sarr (727892)   +15 more
core   +1 more source

Diagnostic Accuracy of Serum‐Based Fibrosis Scores for Clinically Significant Liver Fibrosis in an East Asian Cohort

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Serum‐based fibrosis scores are widely used for noninvasive risk stratification in chronic liver disease; however, direct comparisons across liver disease etiologies remain limited, particularly in Asian populations with a high prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection.
Sheng‐Feng Lin, Chun‐Chao Chang
wiley   +1 more source

Characterization of HIV-1 from patients with virological failure to a boosted protease inhibitor regimen

, 2011
The use of highly active antiretroviral treatment (HAART) regimens with unboosted protease inhibitors (PIs) has resulted in a high level of virological failure primarily due to the development of resistant virus.
Katzenstein, Terese Lea, Court Pedersen, Marie Rathcke Lillemark, Terese Lea Katzenstein, Madsen, Tina Vasehus, Niels Obel, Kronborg, Gitte, Tina Vasehus Madsen, Pedersen, Court, Gitte Kronborg, Gerstoft, Jan, Jan Gerstoft, Lillemark, Marie Rathcke, Louise Bruun Jørgensen, Jørgensen, Louise Bruun, Obel, Niels   +15 more
core   +1 more source

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

Mechanistic insights into HipA‐mediated bacterial persistence: Role of initial cellular states and toxin expression kinetics

mLife, EarlyView.
Abstract Persistent bacteria subpopulations showing multidrug tolerance pose significant challenges to antibiotic therapy. While the HipBA toxin–antitoxin (TA) system is known to play a role in persister formation, existing studies predominantly focus on its kinase activity and intracellular regulatory pathways, with limited attention to the ...
Jing Zhao, Yixiao Xiong, Hongxia Zhao, Jin Wang, Xiaona Fang   +4 more
wiley   +1 more source