Results 141 to 150 of about 22,731 (252)

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

Yeast, EarlyView.
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer, Roy S. K. Walker, Paige E. Erpf, Ian T. Paulsen, Isak S. Pretorius   +4 more
wiley   +1 more source

Evaluation of the cobas plasma separation card to identify HIV-infected patients in virological failure in real-life conditions in Vietnam. [PDF]

PLoS One
Ngo HTH, Nguyen BT, Pham TTP, Le NTH, Pham HB, Nguyen TTT, Ait-Ahmed M, Nguyen TA, Pham TH, Madec Y.   +9 more
europepmc   +1 more source

Twenty‐Five Years of the Environmental Stress Response and the Enduring Power of Yeast in Stress Biology

Yeast, EarlyView.
ABSTRACT All organisms must be able to sense and respond to adverse environments, especially those that threaten cellular integrity. The age of genomics clarified the breadth and specificity of cellular stress responses, including in free‐living microbes directly exposed to a changing environment.
Audrey P. Gasch
wiley   +1 more source

[Early virological failure with long-acting cabotegravir/rilpivirine: description of two cases]. [PDF]

Rev Esp Quimioter
Pena-López MJ, Torres-Martel EG, Santana-Baez S, Bosch-Guerra X.   +3 more
europepmc   +1 more source

Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique. [PDF]

Viruses, 2023
Joaquim L, Miranda MNS, Pimentel V, Martins MDRO, Nhampossa T, Abecasis A, Pingarilho M.   +6 more
europepmc   +1 more source

Comparative Analysis of Stress Adaptation in the Yeast Microbiome of Cactus

Yeast, EarlyView.
Yeasts and related fungi isolated from cacti or nearby non‐cactus plants were characterized phenotypically and genomically, revealing differences that hint at modes of adaptation to the cactus host. ABSTRACT Together with other fungi, yeasts make up a significant component of the plant microbiome. As the planet warms, cacti expand their range.
Alya N. Hussain, Kevin T. Fotso, Michael A. McMurray   +2 more
wiley   +1 more source

M3LoRA: Flexible Task Adaptation via Multiple Low‐Rank Matrices With Mixture‐of‐Subspaces and Minor Singular Components Initialization

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Parameter‐efficient fine‐tuning (PEFT) has become a crucial paradigm for domain adaptation, achieving strong performance by updating only a small fraction of model parameters. Among various PEFT methods, low‐rank adaptation (LoRA) is widely adopted due to its structural simplicity and computational efficiency.
Xu Luo, Yongbin Liu, Chunping Ouyang, Ying Yu, Yang Yang   +4 more
wiley   +1 more source

HIV-1 RNA in Large and Small Plasma Extracellular Vesicles: A Novel Parameter for Monitoring Immune Activation and Virological Failure. [PDF]

J Med Virol
Boucher J, Bazié WW, Goyer B, Alary M, Gilbert C.   +4 more
europepmc   +1 more source

Crisis micro‐learning: A framework for understanding the micro‐flow of policy learning and Australia's COVID‐19 response

Australian Journal of Public Administration, EarlyView.
Abstract COVID‐19 has intensified interest in crisis policy learning, yet the micro‐level interactions among political, bureaucratic, and expert actors remain underexplored. We conceptualise an ideal‐type framework for the micro‐flow of crisis learning, an ordinarily epistemic and context‐specific process of individual‐level interactions, where lessons
Neil Mortimer, Nicholas Bromfield
wiley   +1 more source

Cost-effectiveness of Zvandiri, a community-based support intervention to reduce virological failure in adolescents living with HIV in Zimbabwe: Results of a decision analytical model. [PDF]

PLOS Glob Public Health
Mangenah C, Mavhu W, Willis N, Mufuka J, Bernays S, Mangezi W, Apollo T, Araya R, Weiss HA, Palacios A, Terris-Prestholt F, Cowan FM, Maheswaran H.   +12 more
europepmc   +1 more source