Results 141 to 150 of about 1,735,150 (286)

Determinants of virological failure and antiretroviral drug resistance in Mozambique [PDF]

, 2017
Objectives The objective of this study was to inform public health actions to limit first-line ART failure and HIV drug resistance in Mozambique. Methods This was a cross-sectional study.
Alonso, Pedro, Pou, Christian, Macete, Eusébio, Luis, Leopoldina, Clotet, Bonaventura, Naniche, Denise, Cedeño, Samandhy, Paredes, Roger, Rupérez, María, Letang, Emilio, Moltó, José, Rodríguez, Judith, Menéndez, Clara, Maculuve, Sonia   +13 more
core  

Drug resistance in children with virological failure.

, 2014
3TC, lamivudine (mutation M184V); ARV, antiretroviral; LPVr-NVP, ritonavir boosted lopinavir-based regimen followed by switch to nevirapine-based regimen; NNRTI, non-nucleoside reverse transcriptase inhibitor; NRTI, nucleoside reverse transcriptase ...
Manoranjan Midde (631285), Gerardo Alvarez-Uria (631282), Praveen Kumar Naik (631284), Raghavakalyan Pakam (631283)   +3 more
core   +1 more source

"I take my pills every day, but then it goes up, goes down. I don't know what's going on": Perceptions of HIV virological failure in a rural context in Mozambique. A qualitative research study.

PLoS ONE, 2019
BackgroundHIV prevalence in Mozambique is estimated to be 13.2%. Routine viral load for HIV monitoring was first implemented in the rural area of Tete in 2014.
Ivan Alejandro Pulido Tarquino, Emilie Venables, Jose Manuel de Amaral Fidelis, Ruggero Giuliani, Tom Decroo   +4 more
doaj   +1 more source

Clearance of high‐risk human papillomavirus in patients with cervical intraepithelial neoplasia 2–3 after the loop electrosurgical excision procedure with negative resection margins

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aims to evaluate the longitudinal clearance rates of high‐risk human papillomavirus (hr‐HPV) and the incidence of clinical recurrence (defined by abnormal cytology or histologically confirmed cervical intraepithelial neoplasia; CIN) at 6 and 18 months post‐loop electrosurgical excision procedure (LEEP), characterizing the ...
Praew Sittichivapak, Pattama Chaopotong
wiley   +1 more source

HIV-1 subtype-specific drug resistance on dolutegravir-based antiretroviral therapy: protocol for a multicentre study (DTG RESIST)

BMJ Open
Introduction HIV drug resistance poses a challenge to the United Nation’s goal of ending the HIV/AIDS epidemic. The integrase strand transfer inhibitor (InSTI) dolutegravir, which has a higher resistance barrier, was endorsed by the WHO in 2019 for first-
Stefanie Hossmann, Antoine Jaquet, Matthias Egger, Richard Lessells, Jeremy Ross, Mamatha Sauermann, Tom Loosli, Selma Riedo, Niko Beerenwinkel, Albert Minga, Jennifer Giandhari, Roger D Kouyos   +11 more
doaj   +1 more source

Function‐centered back‐tracing refines obesity‐associated gut microbiome signals beyond abundance‐based profiling

iMetaOmics, EarlyView.
By integrating taxonomic and functional profiling of 1543 adult gut metagenomes, this study identified microbial taxa and enzymatic functions associated with increasing Body Mass Index. Function‐centered taxonomic back‐tracing of branched‐chain amino acid transaminase, nucleotide diphosphatase, and phosphatidylserine decarboxylase revealed only limited
Silvia Petraro, Chiara Tarracchini, Leonardo Mancabelli, Gabriele Andrea Lugli, Francesca Turroni, Marco Ventura, Christian Milani   +6 more
wiley   +1 more source

Sequence‐identical microbial genomes with disparate taxonomy: A large‐scale redundancy analysis in NCBI genome database

iMetaOmics, EarlyView.
Public microbial genome repositories (such as NCBI) contain thousands of sequence‐identical genome assemblies assigned to different taxonomic lineages, potentially inflating microbial diversity and introducing bias into comparative genomics, metagenomics, and pathogen surveillance.
Niharika Saraf, Gaurav Sharma
wiley   +1 more source

Benchmarking gut microbiome indices within and across populations

iMetaOmics, EarlyView.
We compared 10 widely used gut microbiome indices in 12,561 American Gut Project participants and 10 external cohorts, testing how well each distinguished people with healthy lifestyles, responded to 79 environmental factors, and associated with 14 chronic conditions. No single index performed best on all three tasks.
Yu Sun, Yuwei Tang, Jieying Ou, Xinghan Wang, Yiwen Yuan, Xi Fu, Yiqun Deng   +6 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

7.0 Managing virological failure [PDF]

HIV Medicine, 2012
openaire   +1 more source