Results 251 to 260 of about 3,105,782 (329)

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

Molecular Microbiology, EarlyView.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz, Lina Brodskaia, Christiane Fritz, Stefanie Hebecker, Maike K. Tauchert, Jennifer Breisch, Dieter Jahn, Franz Narberhaus, Jürgen Moser, Meriyem Aktas   +9 more
wiley   +1 more source

Outcome of Darunavir-Cobicistat-Based Regimens in HIV-Infected People Who Have Experienced Virological Failure. [PDF]

Drug Des Devel Ther
Alberton F, Galli L, Lolatto R, Candela C, Gianotti N, Chiurlo M, Ranzenigo M, Strano M, Uglietti A, Castagna A.   +9 more
europepmc   +1 more source

The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1

Molecular Microbiology, EarlyView.
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen, Samuel Plante, Berthy Mbuya, Simon Labbé   +3 more
wiley   +1 more source

Join the Green and Sustainable Team: Magnesium Oxide Nanoparticles Boost Broad‐Spectrum Viral Resistance in Solanaceae Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant viruses are so harmful to crops. It is an urgent need to develop modern, environment‐friendly, and sustainable plant viral epidemic‐management strategies that are safe for both human health and the environment. The field of nanotechnology is gaining increased interest in plant science.
Xiao‐Wen Wang, Li Ling, Ke‐Zheng Zhao, Jiangqi Wen, Zhaolin Ji, Xiao‐Ren Chen, Feng Zhu   +6 more
wiley   +1 more source

Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023. [PDF]

HIV Res Clin Pract
Namaganda MM, Mukasa Kafeero H, Nakatumba Nabende J, Kateete DP, Batte C, Wanyengera M, Jjingo D, Joloba M, Kivunike F, Ssewanyana I, Miya Y, Kato D, Ouma S, Kakembo FE, Kanyerezi S, Kabahiita JM, Muwanda F, Mboowa G.   +17 more
europepmc   +1 more source

Mechanisms of Virologic Failure in Hepatitis C and Strategies for Treatment Failure

MOJ Immunology, 2016
openaire   +1 more source

Fatal Chronic Varicella‐Zoster Viral Infection in a Young Man With Chediak–Higashi Syndrome

Pediatric Dermatology, EarlyView.
ABSTRACT Chediak–Higashi syndrome (CHS) is a rare autosomal recessive primary immunodeficiency characterized by partial oculocutaneous albinism, neurologic involvement, and a predisposition to severe infections. Patients are particularly susceptible to developing hemophagocytic lymphohistiocytosis (HLH), which significantly worsens prognosis. We report
Albane Badet, Clément Pruvot, Zoé Manssens, Wadih Abou‐Chahla, Sébastien Buche   +4 more
wiley   +1 more source

Real-world prevalence of integrase inhibitor resistance and virological failure since adoption as guideline-preferred therapy. [PDF]

Drugs Context
Januszka J, Drwiega E, Burgos R, Smith R, Badowski M.   +4 more
europepmc   +1 more source

Photodynamic priming (PDP) targets platinum resistance from chronic perfluoroalkyl substances (PFAS) exposure in ovarian cancer cells

Photochemistry and Photobiology, EarlyView.
PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard, Meghan M. Dillon, Lauren A. Sapienza‐Lundie, Suzanne E. Fenton, Imran Rizvi   +4 more
wiley   +1 more source

Effects of temperature on sexual competition in three kelp species, Pterygophora californica, Nereocystis luetkeana, and Macrocystis pyrifera: Implications for range shifts in foundation species

Phycological Research, EarlyView.
SUMMARY Kelp forests are threatened by rising ocean temperatures. However, the effects of warming on early life stage interactions among co‐occurring kelp species, particularly competitive dynamics and reproductive timing, remain poorly understood. This study investigates the effects of temperature on embryonic sporophyte competitive interactions and ...
Alexis Cynthia Howard Troll
wiley   +1 more source