Results 81 to 90 of about 1,729,369 (285)

Early adherence to antiretroviral medication as a predictor of long-term HIV virological suppression: five-year follow up of an observational cohort. [PDF]

PLoS ONE, 2010
OBJECTIVE: Previous studies have demonstrated a cross-sectional relationship between antiretroviral adherence and HIV virological suppression. We assessed the predictive value of baseline adherence in determining long-term virological failure. DESIGN: We
Nathan Ford, Marta Darder, Tim Spelman, Emi Maclean, Edward Mills, Andrew Boulle   +5 more
doaj   +1 more source

Clinical and Virological Aspects of HBV Reactivation: A Focus on Acute Liver Failure [PDF]

Viruses, 2019
Hepatitis B virus (HBV) reactivation in immunosuppressed patients can cause considerable morbidity and mortality. The aim of our study was to evaluate factors associated with acute liver failure (ALF) in HBV reactivation. Clinical, laboratory, and virological data of 87 patients with HBV reactivation were analyzed retrospectively.
Olympia E. Anastasiou, Martin Theissen, Jens Verheyen, Barbara Bleekmann, Heiner Wedemeyer, Marek Widera, Sandra Ciesek   +6 more
openaire   +5 more sources

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Magnitude and Determinants of Virological Failure Among Patients >15 Years on Anti-Retroviral Therapy in Rural Lesotho Between 2015 and 2019 – A Retrospective Cohort Study [Retraction]

, 2023
Lejone TI, Mahomed O. HIV AIDS (Auckl). 2023;15:611–620. At the author’s request, we, the Editors and Publisher of HIV/AIDS – Research and Palliative Care have retracted the following article.
Lejone TI, Mahomed O
core  

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Factors associated with sustained virological response (SVR) or virological failure/relapse.

, 2018
Factors associated with sustained virological response (SVR) or virological failure/relapse.
Domenico Potenza (5575022), Michele Mazzola (5575025), Donato Bacca (5575037), Giovanni Cenderello (648635), Massimiliano Copetti (174166), Rosanna Santoro (5575046), Ruggero Losappio (5575019), Alessandra Mangia (626370), Natalia Terreni (5575031), Giulio De Stefano (5575028), Nicola Minerva (648643), Valeria Piazzola (5575034), Vincenzo Palmieri (5575040), Fernando Sogari (5575043)   +13 more
core   +1 more source

Characterization of Immune Responses to RBD‐SD1 Nanoparticle Vaccines Derived From ACE2‐Capable HKU5‐CoV‐2, NeoCoV, and HKU5 Merbecoviruses

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann, Jeong Soo Lee, Augustine Duffy, Tong Wang, Bingcheng Huang, James Z. Kurdi, Ajay Inampudi, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +11 more
wiley   +1 more source

Prevalence and determinants of virologic failure among HIV patients on ART in Africa: A systematic review and meta-analysis

Virology Journal
Background The Joint United Nations Programme on HIV/AIDS (UNAIDS) has established the 95-95-95 targets, aiming that by 2030, 95% of individuals on ART will achieve viral suppression.
Ayanaw Dinku Abebe, Worku Chekol Tassew, Yeshiwas Ayale Ferede, Jember Ayelgne Beyene, Muluneh Assefa   +4 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Cumulative hazard estimate for virological failure.

, 2013
Cumulative hazard estimate for virological failure.
Tim Spelman (143159), Andrew Boulle (93997), Emi Maclean (365011), Marta Darder (365010), Nathan Ford (59436), Edward Mills (2348)   +5 more
core   +1 more source