Results 91 to 100 of about 497,332 (389)
Advanced Theory and Simulations, EarlyView.The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak +2 more
wiley +1 more source
The strand-biased transcription of SARS-CoV-2 and unbalanced inhibition by remdesivir
iScience, 2021 Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive single-stranded RNA virus, causes the coronavirus disease 19 pandemic.
Yan Zhao +7 more
doaj
eLife, 2018 Type I interferon (IFN-I) responses are critical for the control of RNA virus infections, however, many viruses, including Dengue (DENV) and Chikungunya (CHIKV) virus, do not directly activate plasmacytoid dendritic cells (pDCs), robust IFN-I producing ...
Brian Webster +12 more
doaj +1 more source
Virology and etiopathogenesis of COVID-19 with special reference to cutaneous implications
Indian Journal of Dermatology, 2021 Severe Acute Respiratory Virus Corona Virus 2 (SARS-CoV-2) has got its name Corona from Latin meaning “crown.” It has crown-like spikes present on the surface, which encloses the RNA, genetic material of this deadly virus.
Rashmi Sarkar +2 more
doaj +1 more source
Molecular characterization of grapevine enamo-like virus, a novel putative member of the genus enamovirus. [PDF]
, 2017 Annals of the XXVII Brazilian Congress of Virology & XI Mercosur Meeting of Virology, Pirienópolis, GO ...
AL RWAHNIH, M. +4 more
core
Entropic control of particle sizes during viral self-assembly [PDF]
, 2013 Morphologic diversity is observed across all families of viruses. Yet these supra-molecular assemblies are produced most of the time in a spontaneous way through complex molecular self-assembly scenarios. The modeling of these phenomena remains a challenging problem within the emerging field of Physical Virology.
arxiv +1 more source
Advanced Science, EarlyView.This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf +7 more
wiley +1 more source
The mechanisms of immune response and evasion by the main SARS-CoV-2 variants
iScience, 2022 Summary: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. SARS-CoV-2 carries a unique group of mutations, and the transmission of the virus has led to the emergence ...
Qiuli Chen +3 more
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Advanced Science, EarlyView.This study provides support for the immunity debt hypothesis, revealing a 131.72% increase in influenza rates during winter and a 161.23% rise in summer, 1 year following the global easing of COVID‐19 restrictions. This study offers empirical evidence of immunity debt on a global level, highlighting the importance of incorporating this concept into the
Li Chen +6 more
wiley +1 more source
TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model
iScience, 2022 Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide outbreak, known as coronavirus disease 2019 (COVID-19). Alongside vaccines, antiviral therapeutics is an important part of the healthcare response to COVID-19 ...
Nunziata Maio +5 more
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