Results 51 to 60 of about 344,467 (249)

SARS-CoV-2 (COVID-19) by the numbers

eLife, 2020
The COVID-19 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers.
Yinon M Bar-On, Avi Flamholz, Rob Phillips, Ron Milo   +3 more
doaj   +1 more source

Varicella Vaccine: a Molecular Variant That May Contribute to Attenuation

mBio, 2022
Varicella was troublesome when varicella vaccine (vOka) was licensed in the United States. Varicella’s yearly death toll was ~100, indirect costs were massive, and varicella threatened immunocompromised children.
Anne A. Gershon, Michael D. Gershon
doaj   +1 more source

The presentation of SARS-CoV-2 peptides by the common HLA-A∗02:01 molecule

iScience, 2021
Summary: CD8+ T cells are crucial for anti-viral immunity; however, understanding T cell responses requires the identification of epitopes presented by human leukocyte antigens (HLA).
Christopher Szeto, Demetra S.M. Chatzileontiadou, Andrea T. Nguyen, Hannah Sloane, Christian A. Lobos, Dhilshan Jayasinghe, Hanim Halim, Corey Smith, Alan Riboldi-Tunnicliffe, Emma J. Grant, Stephanie Gras   +10 more
doaj   +1 more source

virology

, 2022
doc
openaire   +2 more sources

Metagenomics in Virology

, 2021
Metagenomics, i.e., the sequencing and analysis of genomic information extracted directly from clinical or environmental samples, has become a fundamental tool to explore the viral world. Against the background of an extensive viral diversity revealed by metagenomics across many environments, new sequence assembly approaches that reconstruct complete ...
Roux, Simon, Matthijnssens, Jelle, Dutilh, Bas E   +2 more
openaire   +3 more sources

Evolution of Virology: Science History through Milestones and Technological Advancements

Viruses
The history of virology, which is marked by transformative breakthroughs, spans microbiology, biochemistry, genetics, and molecular biology. From the development of Jenner’s smallpox vaccine in 1796 to 20th-century innovations such as ultrafiltration and
Kunlan Zuo, Wanying Gao, Zongzhen Wu, Lei Zhang, Jiafeng Wang, Xuefan Yuan, Chun Li, Qiangyu Xiang, Lu Lu, Huan Liu   +9 more
doaj   +1 more source

Propagation, Inactivation, and Safety Testing of SARS-CoV-2

Viruses, 2020
In late 2019, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, the capital of the Chinese province Hubei.
Alexander S. Jureka, Jesus A. Silvas, Christopher F. Basler   +2 more
doaj   +1 more source

The mechanisms of immune response and evasion by the main SARS-CoV-2 variants

iScience, 2022
Summary: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. SARS-CoV-2 carries a unique group of mutations, and the transmission of the virus has led to the emergence ...
Qiuli Chen, Jiawei Zhang, Peter Wang, Zuyong Zhang   +3 more
doaj   +1 more source

Applications of Deep Mutational Scanning in Virology

Viruses, 2021
Several recently developed high-throughput techniques have changed the field of molecular virology. For example, proteomics studies reveal complete interactomes of a viral protein, genome-wide CRISPR knockout and activation screens probe the importance ...
Thomas D. Burton, Nicholas S. Eyre
doaj   +1 more source

Diagnostic Virology

Clinics in Laboratory Medicine, 1987
Diagnostic virology services are increasingly available and pertinent as the number of useful antiviral agents grows. In this article, current methods of diagnosis are reviewed with special emphasis on rapid procedures. Guidelines for interpretation of cultures and other tests are provided.
openaire   +4 more sources