Q fever outbreak in the terraced vineyards of Lavaux, Switzerland
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini+9 more
wiley +1 more source
Modeling long-term longitudinal HIV dynamics with application to an AIDS clinical study [PDF]
A virologic marker, the number of HIV RNA copies or viral load, is currently used to evaluate antiretroviral (ARV) therapies in AIDS clinical trials. This marker can be used to assess the ARV potency of therapies, but is easily affected by drug exposures, drug resistance and other factors during the long-term treatment evaluation process.
arxiv +1 more source
Uncovering Virus-Virus Interactions by Unifying Approaches and Harnessing High-Throughput Tools
Virus-host interactions have received much attention in virology. Virus-virus interactions can occur when >1 virus infects a host and can be deemed social when one virus affects the fitness of another virus, as in the well-known case of superinfection ...
Samuel L. Díaz-Muñoz
doaj +1 more source
Cell Cultures for Virology: Usability, Advantages, and Prospects
Virus detection in natural and clinical samples is a complicated problem in research and diagnostics. There are different approaches for virus isolation and identification, including PCR, CRISPR/Cas technology, NGS, immunoassays, and cell-based assays ...
A. A. Dolskiy, I. Grishchenko, D. Yudkin
semanticscholar +1 more source
Old Enemy with a New Face: Re-emerging Monkeypox Disease – An Update
Human monkeypox (MPX), a multi-country re-emerging disease, is rapidly spreading around the world. The etiological agent of this disease, Monkeypox virus (MPXV), is a DNA virus classified into three genetic types (West Africa, Congo Basin clade, and one ...
Md. Aminul Islam+5 more
doaj +1 more source
Current opinion in virology: structural virology
Current Opinion in Virology 1 (2011) 81-83.
Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610, USA ( host institution )+2 more
openaire +3 more sources
Varicella Vaccine: a Molecular Variant That May Contribute to Attenuation
Varicella was troublesome when varicella vaccine (vOka) was licensed in the United States. Varicella’s yearly death toll was ~100, indirect costs were massive, and varicella threatened immunocompromised children.
Anne A. Gershon, Michael D. Gershon
doaj +1 more source
A pharmacokinetic -- viral kinetic model describes the effect of alisporivir monotherapy or in combination with peg-IFN on 2 hepatitis C virologic response [PDF]
Alisporivir is a cyclophilin inhibitor with demonstrated in vitro and in vivo activity against hepatitis C 11 virus (HCV). We estimated antiviral effectiveness of alisporivir alone or in combination with 12 pegylated-Inteferon (peg-IFN) in 88 patients infected with different HCV genotypes treated for four 13 weeks.
arxiv +1 more source
Virus goes viral: an educational kit for virology classes
Viruses are the most numerous entities on Earth and have also been central to many episodes in the history of humankind. As the study of viruses progresses further and further, there are several limitations in transferring this knowledge to undergraduate
Gabriel Augusto Pires de Souza+5 more
semanticscholar +1 more source
An Update on African Swine Fever Virology
Animal diseases constitute a continuing threat to animal health, food safety, national economy, and the environment. Among those, African swine fever (ASF) is one of the most devastating viruses affecting pigs and wild suids due to the lack of vaccine or
A. Karger+8 more
semanticscholar +1 more source