Results 81 to 90 of about 497,332 (389)

Functional Polymer Nanocomposites by Gas Aggregation Cluster Source and Initiated Chemical Vapor Deposition

Advanced Materials Technologies, EarlyView.
In this work, a gas aggregation cluster source and an initiated chemical vapor deposition are combined in a single vacuum reactor. With this setup polymer thin films can be combined with functional nanoparticles. As a proof‐of‐concept PTFE is combined with silver nanoparticles and tested in antibacterial, antiviral, and anticancer applications ...
Torge Hartig, Joschka Paulsen, Jonas Drewes, Asmaa T. Mohamed, Nasra F. Abdel Fattah, Cedric Hinrichs, Felix Pohl, Stefan Rehders, Ainura Aliyeva, Henning Wieker, Jörg Wiltfang, Salih Veziroglu, Samah A Loutfy, Oral Cenk Aktas, Alexander Vahl, Thomas Strunskus, Aydin Gülses, Amal Amin, Stefan Schröder, Franz Faupel   +19 more
wiley   +1 more source

Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile

iScience, 2021
Summary: Broadly neutralizing antibodies (bnAbs) against HIV-1 are frequently associated with the presence of autoreactivity/polyreactivity, a property that can limit their use as therapeutic agents.
Edurne Rujas, Daniel P. Leaman, Sara Insausti, Pablo Carravilla, Miguel García-Porras, Eneko Largo, Izaskun Morillo, Rubén Sánchez-Eugenia, Lei Zhang, Hong Cui, Ibon Iloro, Félix Elortza, Jean-Philippe Julien, Christian Eggeling, Michael B. Zwick, Jose M.M. Caaveiro, José L. Nieva   +16 more
doaj  

Nipah virus vector sequences in COVID-19 patient samples sequenced by the Wuhan Institute of Virology [PDF]

arXiv, 2021
We report the detection of Nipah virus in an infectious clone format, a BSL4-level pathogen and CDC-designated Bioterrorism Agent, in raw RNA-Seq sequencing reads deposited by the Wuhan Institute of Virology (WIV) produced from five December 2019 patients infected with SARS-CoV-2.
arxiv  

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Gut dsDNA virome shows diversity and richness alterations associated with childhood obesity and metabolic syndrome

iScience, 2021
Summary: Changes in the human gut microbiome are associated with obesity and metabolic syndrome, but the role of the gut virome in both diseases remains largely unknown. We characterized the gut dsDNA virome of 28 school-aged children with healthy normal-
Shirley Bikel, Gamaliel López-Leal, Fernanda Cornejo-Granados, Luigui Gallardo-Becerra, Rodrigo García-López, Filiberto Sánchez, Edgar Equihua-Medina, Juan Pablo Ochoa-Romo, Blanca Estela López-Contreras, Samuel Canizales-Quinteros, Abigail Hernández-Reyna, Alfredo Mendoza-Vargas, Adrian Ochoa-Leyva   +12 more
doaj  

Novel Kac-Moody-type affine extensions of non-crystallographic Coxeter groups [PDF]

J. Phys. A: Math. Theor. 45 (2012) 285202, 2011
Motivated by recent results in mathematical virology, we present novel asymmetric Z[tau]-integer-valued affine extensions of the non-crystallographic Coxeter groups H_2, H_3 and H_4 derived in a Kac-Moody-type formalism. In particular, we show that the affine reflection planes which extend the Coxeter group H_3 generate (twist) translations along 2-, 3-
arxiv   +1 more source

Real-time PCR in virology.

Nucleic Acids Research, 2002
The use of the polymerase chain reaction (PCR) in molecular diagnostics has increased to the point where it is now accepted as the gold standard for detecting nucleic acids from a number of origins and it has become an essential tool in the research ...
I. Mackay, K. Arden, A. Nitsche
semanticscholar   +1 more source

Enhanced Epithelial Cell Uptake of Glycol Chitosan‐Coated PLGA Nanoparticles for Oral Drug Delivery

Advanced Therapeutics, EarlyView.
Here, glycol chitosan (GC)‐coated PLGA NPs are developed to enhance oral drug delivery by enabling dual‐pathway endocytosis via clathrin‐ and caveolae‐mediated mechanisms. Alginate layering coating on GC‐PLGA further improves oral insulin delivery, achieving sustained glucose reduction in diabetic mice.
Huiwen Pang, Wenxuan Yu, Youzhi Wu, Xuqiang Nie, Guojun Huang, Zhi Ping Xu, Chen Chen, Felicity Y. Han   +7 more
wiley   +1 more source

Providing a Safe, In-Person, Residential College Experience During the COVID-19 Pandemic

Frontiers in Public Health, 2021
Due to the COVID-19 pandemic, higher education institutions were forced to make difficult decisions regarding the 2020–2021 academic year. Many institutions decided to have courses in an online remote format, others decided to attempt an in-person ...
Scott A. Travis, Aaron A. Best, Kristyn S. Bochniak, Nicole D. Dunteman, Jennifer Fellinger, Peter D. Folkert, Timothy Koberna, Benjamin G. Kopek, Brent P. Krueger, Jeff Pestun, Michael J. Pikaart, Cindy Sabo, Alex J. Schuitema   +12 more
doaj   +1 more source

The birth of virology. [PDF]

Antonie van Leeuwenhoek, 1997
This quote is from Cicero’s ‘De Amicitia’ (23, 87) — I happen to remember it from my days at school, and it comes in conveniently to start a talk on the birth of virology, my occupation since three decades. In Cicero’s quote it is said of an intransigent person that she ‘...still cannot be without somebody where to spit out the venom of one’s own ...
openaire   +3 more sources