Results 81 to 90 of about 461,055 (348)
Advanced Science, EarlyView.This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao +13 more
wiley +1 more source
Infection and Drug Resistance, 2022 Giuliana Lo Cascio,1– 3 Alda Bazaj,1 Laura Trovato,2,4 Silvana Sanna,2,5 Stefano Andreoni,2,6 Elisabetta Blasi,2,7 Marco Conte,2,8 Paolo Fazii,2,9 Ester Oliva,10 Valentina Lepera,11 Gianluigi Lombardi,2,11 Claudio Farina2,10 1Clinical Microbiology and ...
Lo Cascio G +11 more
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Hendra Virus Infection in Dog, Australia, 2013
Emerging Infectious Diseases, 2015 Hendra virus occasionally causes severe disease in horses and humans. In Australia in 2013, infection was detected in a dog that had been in contact with an infected horse.
Peter D. Kirkland +10 more
doaj +1 more source
Modelling the structure of full-length Epstein-Barr virus nuclear antigen 1 [PDF]
, 2014 Epstein-Barr virus (EBV) is a clinically important human virus associated with several cancers and is the etiologic agent of infectious mononucleosis. The viral nuclear antigen-1 (EBNA1) is central to the replication and propagation of the viral genome
Gatherer, Derek +2 more
core +1 more source
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Phosphorylation of TGB1 by protein kinase CK2 promotes barley stripe mosaic virus movement in monocots and dicots. [PDF]
, 2015 The barley stripe mosaic virus (BSMV) triple gene block 1 (TGB1) protein is required for virus cell-to-cell movement. However, little information is available about how these activities are regulated by post-translational modifications. In this study, we
Han, Chenggui +11 more
core +2 more sources
RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors
Advanced Science, EarlyView.RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao +7 more
wiley +1 more source
Surveillance and monitoring for endemic and exotic virus diseases of cotton [PDF]
, 2015 The aims of this project will provide capacity in virology expertise to help protect Australian cotton from virus diseases including both existing and those that pose significant biosecurity threats.
Sharman, Murray
core +1 more source
Advanced Science, EarlyView.Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang +13 more
wiley +1 more source
Development survey of neurovirology
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 As a new subdiscipline, neurovirology derives from medical virology and neurology. Its research field includes both clinical practice of viral infectious diseases of the nervous system and fundamental research of medical virology.
De-xin WANG
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