Results 111 to 120 of about 1,645 (202)
Toward a Metagenomic Understanding on the Bacterial Composition and Resistome in Hong Kong Banknotes [PDF]
Currency is possibly one of the main media transmitting pathogens and drug resistance due to its wide circulation in daily life. In this study, we made a comprehensive characterization of the bacterial community present on banknotes collected from ...
Baker, DM +13 more
core +1 more source
MELK is not necessary for the proliferation of basal-like breast cancer cells [PDF]
Thorough preclinical target validation is essential for the success of drug discovery efforts. In this study, we combined chemical and genetic perturbants, including the development of a novel selective maternal embryonic leucine zipper kinase (MELK ...
Adams +56 more
core +3 more sources
A Bioinformatics View of Glycan–Virus Interactions
Evidence of the mediation of glycan molecules in the interaction between viruses and their hosts is accumulating and is now partially reflected in several online databases. Bioinformatics provides convenient and efficient means of searching, visualizing,
Philippe Le Mercier +6 more
doaj +1 more source
In this chapter we discuss changing approaches to viral discovery and human health, summarize the current understanding of the human-associated viral community, and review contemporary methods in viral metagenomics. The virome is the community of viruses that populate an organism or ecosystem at any given time. This includes the “core” set of commensal
Haynes, Matthew, Rohwer, Forest
openaire +1 more source
The human virome is the collection of viruses found in human, including viruses that infect eucaryotic cells, bacteriophages and virus-derived genetic elements in host chromosomes that can influence host-genes expression. Most of the recent knowledges regarding the human virome were driven by advances in high-throughput, deep sequencing approaches ...
openaire +1 more source
GPR54 regulates non-small cell lung cancer development via dopa decarboxylase
Non-small cell lung cancer (NSCLC), the most common type of lung cancer, is a leading cause of cancer death. G protein-coupled receptor 54 (GPR54) plays a role in cancer development by interacting with its endogenous ligand kisspeptin encoded by the ...
Hyun-Ha Hwang +5 more
doaj +1 more source
O microbioma intestinal humano e as suas implicações na saúde [PDF]
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraO Microbioma Humano é definido como a comunidade de microrganismos e dos seus ...
Gonçalves, Sílvia Raquel França
core
Recent advances in deep learning and language models for studying the microbiome
Recent advancements in deep learning, particularly large language models (LLMs), made a significant impact on how researchers study microbiome and metagenomics data. Microbial protein and genomic sequences, like natural languages, form a language of life,
Binghao Yan +5 more
doaj +1 more source
We collected 2,535 organ and 274 blood samples from 466 healthy and 50 dead wild boars across 127 locations in 26 provincial regions of China. These samples were subjected to a combination of RNA and DNA viromic analyses, which resulted in a data set of 9,281 viral metagenomes.
openaire +1 more source
Rodents as potential reservoirs for toroviruses
Background Emerging zoonotic viruses pose a significant threat to global health. The order Nidovirales includes diverse viruses, such as coronaviruses, which are well known for their zoonotic potential.
Jaime Buigues +5 more
doaj +1 more source

