Results 101 to 110 of about 18,764 (290)

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli, Seshasai Srinivasan, Amin Reza Rajabzadeh   +2 more
wiley   +1 more source

Nano-modified viruses prime the tumor microenvironment and promote the photodynamic virotherapy in liver cancer

Journal of Biomedical Sciences
Background As of 2020, hepatocellular carcinoma (HCC), a form of liver cancer, stood as the third most prominent contributor to global cancer-related mortality. Combining immune checkpoint inhibitors (ICI) with other therapies has shown promising results
D. Ou, Z. Liao, I. Kempson, Lin Li, Pan-Chyr Yang, S. Tseng   +5 more
semanticscholar   +1 more source

Clinical activity of single-dose systemic oncolytic VSV virotherapy in patients with relapsed refractory T-cell lymphoma

Blood Advances, 2022
Key Points One intravenous dose of oncolytic VSV has single-agent activity in patients with relapsed refractory T-cell lymphoma. Direct oncolytic tumor cell killing and subsequent immune cell activation were observed, resulting in durable remissions in ...
Joselle M. Cook, K. Peng, T. Witzig, S. Broski, J. Villasboas, J. Paludo, M. Patnaik, Vincent Rajkumar, A. Dispenzieri, N. Leung, F. Buadi, N. Bennani, S. Ansell, Lianwen Zhang, N. Packiriswamy, Baskar Balakrishnan, B. Brunton, Marissa Giers, B. Ginos, A. Dueck, S. Geyer, M. Gertz, R. Warsame, R. Go, S. Hayman, D. Dingli, Shaji K. Kumar, P. L. Bergsagel, J. Muñoz, W. Gonsalves, T. Kourelis, Eli Muchtar, P. Kapoor, R. Kyle, Yi Lin, M. Siddiqui, A. Fonder, M. Hobbs, Y. Hwa, Shruthi Naik, S. Russell, M. Lacy   +41 more
semanticscholar   +1 more source

In Situ Sustained Delivery of Tumor Cell‐Derived Extracellular Nanovesicles With Oncolytic Adenoviruses for Potentiating Cancer Immunotherapy

Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
ABSTRACT Oncolytic adenoviruses (OVs) can directly eliminate cancer cells and subsequently activate immune responses, exhibiting potent antitumor therapeutics. However, it was observed that the immune cells can also be lysed during viral treatment, evidently dampening the OVs‐mediated antitumor immune response.
Tianye Wang, Sheng Zhao, Zao Ji, Zhonggui He, Zhenguo Cheng, Zhen Gu, Yuqi Zhang, Jin Sun, Funan Liu, Mengchi Sun   +9 more
wiley   +1 more source

Oncolytic Viruses for Cancer Therapy: Barriers and Recent Advances

Molecular Therapy: Oncolytics, 2019
Oncolytic viruses (OVs) are powerful new therapeutic agents in cancer therapy. With the first OV (talimogene laherparepvec [T-vec]) obtaining US Food and Drug Administration approval, interest in OVs has been boosted greatly.
Meijun Zheng, Jianhan Huang, Aiping Tong, Hui Yang   +3 more
doaj   +1 more source

A progressive stage IIIB melanoma treated with oncolytic ECHO-7 virus: A case report

SAGE Open Medical Case Reports, 2020
Melanoma is an aggressive skin cancer form with a grave prognosis. Current results suggest that oncolytic virus treatment of melanoma has a high therapeutic potential. ECHO-7 (Rigvir) is the first oncolytic virus registered in Latvia.
Vladimirs Sorokins, Andra Tilgase, Evija Olmane, Sergejs Isajevs, Tatjana Zablocka, Agnija Rasa, Pēteris Alberts   +6 more
doaj   +1 more source

Combining of Oncolytic Virotherapy and Other Immunotherapeutic Approaches in Cancer: A Powerful Functionalization Tactic

Global Challenges, 2022
Oncolytic viruses have found a good place in the treatment of cancer. Administering oncolytic viruses directly or by applying genetic changes can be effective in cancer treatment through the lysis of tumor cells and, in some cases, by inducing immune ...
Hai Zou, X. Mou, Biao Zhu
semanticscholar   +1 more source

Itaconate‐Related Gene Signatures as Prognostic Markers in Colon Cancer: Insights From Transcriptomic and Spatial Analysis

Human Mutation, Volume 2026, Issue 1, 2026.
Colon cancer is one of the most prevalent malignant tumors. Accurate evaluation of patient prognosis and optimization of treatment strategies continue to be major research focuses in colon cancer. Based on The Cancer Genome Atlas (TCGA) database, this study is the first to comprehensively analyze the expression, biological roles, and prognosis of ...
Tingting Zhang, Jianchao Meng, Qingyun Wang, Peng Zhang, Hui Li, Hailang Wei, Denggang Chen, Chen Bai, Sujit Nair   +8 more
wiley   +1 more source

Oncolytic virotherapy provides a potent therapy option for squamous bladder cancer. [PDF]

Sci Rep
Pannhausen J, Wirtz J, Mantwill K, Holm PS, Schwamborn K, Jonigk DD, Gschwend JE, Rose M, Gaisa NT, Nawroth R.   +9 more
europepmc   +3 more sources

Attenuated Semliki Forest virus for cancer treatment in dogs : safety assessment in two laboratory Beagles [PDF]

, 2015
Background: Dogs suffer from spontaneous tumors which may be amenable to therapies developed for human cancer patients, and dogs may serve as large-animal cancer models.
Anttila, Marjukka O., Autio, Karoliina P. M., Hemminki, Akseli, Hinkkanen, Ari E., Niittykoski, Minna, Ruotsalainen, Janne J., Vähä-Koskela, Markus J. V., Waris, Matti   +7 more
core   +1 more source