Results 101 to 110 of about 13,459 (185)

Effects of Newcastle Disease Virus on Gene Expression Profiling, and Nitric Oxide and Glutathione Production in MCF-7 Breast Canser Cell Line [PDF]

, 2011
Breast cancer is a major cause of death for many women around the world. Progress has been made in the survival of breast cancer patients due to improved understanding of the molecular processes, diagnostic techniques and knowledge of the treatment using
Ali, Mohamed Kalid
core  

Human Menstrual Blood-Derived Mesenchymal Stem Cells as Potential Cell Carriers for Oncolytic Adenovirus

Stem Cells International, 2017
Antitumor efficacy of systemically administered oncolytic adenoviruses (OAdv) is limited due to diverse factors such as liver sequestration, neutralizing interactions in blood, elimination by the immune system, and physical barriers in tumors.
R. Moreno, L. A. Rojas, Felip Vilardell Villellas, Vanessa Cervera Soriano, J. García-Castro, C. A. Fajardo, R. Alemany   +6 more
doaj   +1 more source

Markedly enhanced intratumoral spread and antitumor effect of oncolytic adenovirus expressing decorin [PDF]

, 2008
With the aim of improving viral distribution and tumor penetration, we have engineered decorin expressing replication-incompetent (dl-LacZ-DCNG) and -competent (Ad-[DELTA]E1B-DCNG) adenoviruses.
A-Rum Yoon, Chae-Ok Yun, Daniela G. Seidler, Hoguen Kim, Il-Kyu Choi, Ji Young Yoo, Joo-Hang Kim, Young-Sook Lee   +7 more
core   +1 more source

Patient-derived tumoroids and proteomic signatures: tools for early drug discovery

Frontiers in Immunology
Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties.
Hélène Lê, Hélène Lê, Jules Deforges, Pasquale Cutolo, Anissa Lamarque, Guoqiang Hua, Véronique Lindner, Véronique Lindner, Shreyansh Jain, Jean-Marc Balloul, Nadia Benkirane-Jessel, Eric Quéméneur   +11 more
doaj   +1 more source

Virotherapy-recruited PMN-MDSC infiltration of mesothelioma blocks antitumor CTL by IL-10-mediated dendritic cell suppression

OncoImmunology, 2019
Antitumor cytotoxic T lymphocytes (CTLs) are essential for immune surveillance, yet the blockade of eliciting such CTLs during oncolytic virotherapy remains incompletely understood.
Zhiwu Tan, Li Liu, Mei Sum Chiu, Ka-Wai Cheung, Chi Wing Yan, Zhe Yu, Boon Kiat Lee, Wan Liu, Kwan Man, Zhiwei Chen   +9 more
doaj   +1 more source

Syöpää sairastavien potilaiden elämänlaatu virushoitokokeilun aikana [PDF]

, 2013
Opinnäytetyön tarkoituksena on kuvata syöpää sairastavien potilaiden kokemaa elämänlaatua ja sen muuttumista virushoitokokeilun aikana. Opinnäytetyön tavoitteena on pohtia virushoidon merkitystä potilaiden kokemaan elämänlaatuun ja tuottaa tietoa ...
Helander, Marjukka, Vesala, Tuulikki
core  

Analisa Kestabilan Model Matematika untuk Penyembuhan Kanker Menggunakan Oncolytic Virotherapy [PDF]

, 2016
. Oncolytic virotherapy is one type of cancer treatment using oncolytic virus. In this paper, we will present a mathematical model for treatment of cancer using oncolytic virotherapy with the burst size of a virus (the number of new viruses released ...
Via Novellina, Via Novellina
core  

Oncolytic adenoviruses encoding bispecific T cell engagers or a novel trispecific T cell engager for dual-targeting of c-MET and EGFR

Molecular Therapy: Oncology
This study reports a strategy to overcome immune escape of tumors during viro-immunotherapy due to tumor heterogeneity. We pursued a dual-targeting approach of epidermal growth factor receptor (EGFR) and cellular mesenchymal epithelial transition factor (
Martin A. Boos, Oliver Seifert, Stefanie Sawall, Jessica Genz, Annika Huber, Ilse Hofmann, Roland E. Kontermann, Guy Ungerechts, Dirk M. Nettelbeck   +8 more
doaj   +1 more source

Experimental treatment modalities for osteosarcoma: Preclinical studies on virotherapy, chemotherapy and small molecule therapy [PDF]

, 2008
Kaspers, G.J.L. [Promotor]Wuisman, P.I.J.M. [Promotor]Beusechem, V.W.
Graat, H.C.A.
core   +2 more sources

Current Development of Virotherapy in Breast Cancer: A Brief Review

Acta Medica Bulgarica
Breast cancer is the cancer with the greatest incidence in the world by 2020. This cancer has a high mortality rate, has the capability of metastasizing, and causes damage to important organs of the human body.
Sasmana I., Putri P., Dewi N., Supadmanaba I., Wihandani D.   +4 more
doaj   +1 more source