Results 111 to 120 of about 13,638 (219)

Biological Ablation of Sentinel Lymph Node Metastasis in Submucosally Invaded Early Gastrointestinal Cancer [PDF]

open access: yes, 2014
Currently, early gastrointestinal cancers are treated endoscopically, as long as there are no lymph node metastases. However, once a gastrointestinal cancer invades the submucosal layer, the lymph node metastatic rate rises to higher than 10%. Therefore,
Fujiwara, Toshiyoshi   +11 more
core   +1 more source

Editorial: Oncolytic virotherapy

open access: yesFrontiers in Molecular Biosciences, 2023
Ahmed Majeed Al-Shammari   +2 more
openaire   +3 more sources

Human Menstrual Blood-Derived Mesenchymal Stem Cells as Potential Cell Carriers for Oncolytic Adenovirus

open access: yesStem Cells International, 2017
Antitumor efficacy of systemically administered oncolytic adenoviruses (OAdv) is limited due to diverse factors such as liver sequestration, neutralizing interactions in blood, elimination by the immune system, and physical barriers in tumors.
R. Moreno   +6 more
doaj   +1 more source

How Can We Stop Cancer? [PDF]

open access: yes, 2020
Cancer is a disease that humans have been struggling to combat for centuries. It originates from the accumulation of several mutations over the life of a cell that causes it to evade cell death and multiply rapidly.
Current, Joseph R
core   +1 more source

Immunotherapeutic potential of oncolytic vaccinia virus [PDF]

open access: yes, 2014
The concept of oncolytic viral therapy was based on the hypothesis that engineering tumor-selectivity into the replication potential of viruses would permit direct destruction of tumor cells as a result of viral-mediated lysis, resulting in amplification
Thorne, SH
core   +1 more source

Cytolytic Effects of Newcastle Disease Virus Strain Af2240 on Dbtrg.05mg and U-87mg Brain Tumor Cell Lines [PDF]

open access: yes, 2008
Newcastle disease virus (NDV) is a potential oncolytic agent as it can replicate up to 10,000 times better in human cancer cells than in most normal human cells. Several strains of NDV were reported to induce cytolysis to various cancerous cell lines.
Saeed, Rola Ali
core  

Patient-derived tumoroids and proteomic signatures: tools for early drug discovery

open access: yesFrontiers in Immunology
Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties.
Hélène Lê   +11 more
doaj   +1 more source

Engineered bovine herpesvirus type 4: a new tool against glioma stem-like cells? [PDF]

open access: yes, 2015
Glioblastoma (GBM) is a grade IV primary brain tumor (WHO 2007). Despite last progresses in surgery, chemo- and radiotherapy, this brain tumor is still incurable and it always recurs (Stupp et al, 2009).
Moschioni, Chiara
core  

Syöpää sairastavien potilaiden elämänlaatu virushoitokokeilun aikana [PDF]

open access: yes, 2013
Opinnäytetyön tarkoituksena on kuvata syöpää sairastavien potilaiden kokemaa elämänlaatua ja sen muuttumista virushoitokokeilun aikana. Opinnäytetyön tavoitteena on pohtia virushoidon merkitystä potilaiden kokemaan elämänlaatuun ja tuottaa tietoa ...
Helander, Marjukka, Vesala, Tuulikki
core  

Oncolytic adenoviruses encoding bispecific T cell engagers or a novel trispecific T cell engager for dual-targeting of c-MET and EGFR

open access: yesMolecular Therapy: Oncology
This study reports a strategy to overcome immune escape of tumors during viro-immunotherapy due to tumor heterogeneity. We pursued a dual-targeting approach of epidermal growth factor receptor (EGFR) and cellular mesenchymal epithelial transition factor (
Martin A. Boos   +8 more
doaj   +1 more source

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