Results 91 to 100 of about 10,988 (206)
Cancer Science, Volume 117, Issue 7, Page 2007-2020, July 2026.OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan +8 more
wiley +1 more source
Applications of Mathematical Modelling in Oncolytic Virotherapy and Immunotherapy [PDF]
, 2019 Cancer is a devastating disease that touches almost everyone and finding effective treatments presents a highly complex problem, requiring extensive multidisciplinary research.
Jenner, A., Jenner, Adrianne Lena
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Molecular Therapy: OncologyNUT carcinoma (NC) is a rare, yet aggressive disease (median survival of 6.5 months) of the young defined by a translocation of the nuclear protein in testis gene 1 (NUTM1).
Rieka C. Buchenau +13 more
doaj +1 more source
Stem Cells International, 2017 Antitumor efficacy of systemically administered oncolytic adenoviruses (OAdv) is limited due to diverse factors such as liver sequestration, neutralizing interactions in blood, elimination by the immune system, and physical barriers in tumors.
R. Moreno +6 more
doaj +1 more source
RNA viruses as virotherapy agents [PDF]
Cancer Gene Therapy, 2002 RNA viruses are rapidly emerging as extraordinarily promising agents for oncolytic virotherapy. Integral to the lifecycles of all RNA viruses is the formation of double-stranded RNA, which activates a spectrum of cellular defense mechanisms including the activation of PKR and the release of interferon.
openaire +2 more sources
Emerging role of Natural killer cells in oncolytic virotherapy
, 2015 Rauf Bhat, Jean Rommelaere Division of Tumor Virology, German Cancer Research Center, Heidelberg, Germany Abstract: Natural killer (NK) cells constitute a subtype of lymphocytes that initiate innate immune responses against tumors and virus-infected ...
Bhat R, Rommelaere J
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Virotherapy, gene transfer and immunostimulatory monoclonal antibodies
, 2012 Virotherapy, gene transfer and immunostimulatory monoclonal ...
PK Darcy (14473242) +6 more
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Applications of Oncolytic Virotherapy in Malignant Tumors
Oncolytic virotherapy, an emerging cancer immunotherapy modality, has attracted much attention in recent years due to its power to selectively infect and eradicate tumor cells while simultaneously activating host anticancer immune responses.
Yining Wang
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source