Results 101 to 110 of about 13,638 (219)

Literature review: Virus and cancer [PDF]

open access: yes, 2017
Traballo fin de grao (UDC.CIE). Bioloxía. Curso 2016/2017[Abstract] Cancer is one of the main causes of global mortality, and even though it is considered to be a non-communicable disease, several infectious agents have been found to contribute to ...
Carreira Santos, Sofía
core  

Adenovirus-Mediated Sensitization to the Cytotoxic Drugs Docetaxel and Mitoxantrone Is Dependent on Regulatory Domains in the E1ACR1 Gene-Region [PDF]

open access: yes, 2012
Oncolytic adenoviruses have shown promising efficacy in clinical trials targeting prostate cancers that frequently develop resistance to all current therapies.
Daniel Öberg   +7 more
core   +3 more sources

Itaconate‐Related Gene Signatures as Prognostic Markers in Colon Cancer: Insights From Transcriptomic and Spatial Analysis

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Colon cancer is one of the most prevalent malignant tumors. Accurate evaluation of patient prognosis and optimization of treatment strategies continue to be major research focuses in colon cancer. Based on The Cancer Genome Atlas (TCGA) database, this study is the first to comprehensively analyze the expression, biological roles, and prognosis of ...
Tingting Zhang   +8 more
wiley   +1 more source

Virotherapy in Head and Neck Cancer

open access: yesOral Oncology Reports
Head and neck cancer, comprising a diverse group of malignancies, presents significant challenges in terms of treatment efficacy and patient outcomes.
Zhan Wang
doaj   +1 more source

HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy [PDF]

open access: yes, 2014
Several clinical trials have shown that oncolytic herpes simplex virus type 1 (oHSV-1) can be safely administered to patients. However, virus replication in tumor tissue has generally not been monitored in these oHSV clinical trials, and the data suggest
Decklever, T D   +4 more
core   +1 more source

Fixed Point Analysis for Cauchy‐Type Variable‐Order Fractional Differential Equations With Finite Delay

open access: yesInternational Journal of Differential Equations, Volume 2026, Issue 1, 2026.
This paper presents a comprehensive analysis of the existence, uniqueness, and Ulam–Hyers stability of solutions for a class of Cauchy‐type nonlinear fractional differential equations with variable order and finite delay. The motivation for this study lies in the increasing importance of variable‐order fractional calculus in modeling real‐world systems
Souhila Sabit   +5 more
wiley   +1 more source

The oncolytic vesicular stomatitis virus VSV-GP shows profound oncolytic activity in NUT-carcinoma cell lines

open access: yesMolecular Therapy: Oncology
NUT carcinoma (NC) is a rare, yet aggressive disease (median survival of 6.5 months) of the young defined by a translocation of the nuclear protein in testis gene 1 (NUTM1).
Rieka C. Buchenau   +13 more
doaj   +1 more source

Targeting oncogenic fusion-driven NUT carcinoma with CRISPR-Cas9 genome editing

open access: yesMolecular Therapy: Oncology
NUT carcinoma (NC) is a highly aggressive malignancy characterized by an oncogenic fusion gene incorporating the NUTM1 gene. To date, no established treatment options exist.
Maxim F. Carle   +7 more
doaj   +1 more source

IgE‐Sensitized Mast Cells: A Programmable Platform for Antigen‐Triggered Oncolytic Virotherapy

open access: yes
MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
Lin Chen, Yu‐Xuan Jin, Jin‐Lyu Sun
wiley   +1 more source

CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter [PDF]

open access: yes, 2016
Ad vectors are promising delivery vehicles for cancer therapeutic interventions. However, their application is limited by promiscuous tissue tropism and hepatotoxicity. This limitation can be avoided by altering the native tropism of Ads so that they can
Bhatia, Shilpa   +4 more
core   +3 more sources

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