Results 101 to 110 of about 10,988 (206)

Editorial: Oncolytic virotherapy

Frontiers in Molecular Biosciences, 2023
Ahmed Majeed Al-Shammari, Pier Paolo Piccaluga, Pier Paolo Piccaluga   +2 more
openaire   +3 more sources

Analisa Kestabilan Model Matematika untuk Penyembuhan Kanker Menggunakan Oncolytic Virotherapy [PDF]

, 2016
. Oncolytic virotherapy is one type of cancer treatment using oncolytic virus. In this paper, we will present a mathematical model for treatment of cancer using oncolytic virotherapy with the burst size of a virus (the number of new viruses released ...
Via Novellina, Via Novellina
core  

Virotherapy-recruited PMN-MDSC infiltration of mesothelioma blocks antitumor CTL by IL-10-mediated dendritic cell suppression

OncoImmunology, 2019
Antitumor cytotoxic T lymphocytes (CTLs) are essential for immune surveillance, yet the blockade of eliciting such CTLs during oncolytic virotherapy remains incompletely understood.
Zhiwu Tan, Li Liu, Mei Sum Chiu, Ka-Wai Cheung, Chi Wing Yan, Zhe Yu, Boon Kiat Lee, Wan Liu, Kwan Man, Zhiwei Chen   +9 more
doaj   +1 more source

Patient-derived tumoroids and proteomic signatures: tools for early drug discovery

Frontiers in Immunology
Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties.
Hélène Lê, Hélène Lê, Jules Deforges, Pasquale Cutolo, Anissa Lamarque, Guoqiang Hua, Véronique Lindner, Véronique Lindner, Shreyansh Jain, Jean-Marc Balloul, Nadia Benkirane-Jessel, Eric Quéméneur   +11 more
doaj   +1 more source

A multiscale mathematical model for oncolytic virotherapy

, 2009
One of the most promising strategies to treat cancer is attacking it with viruses. Oncolytic viruses can kill tumor cells specifically or induce anticancer immune response. A multiscale model for virotherapy of cancer is investigated through simulations.
Martins, Marcelo L., Binny, Christopher, M. L. Martins, Paiva, Leticia R., C. Binny, L. R. Paiva, S. C. Ferreira, Ferreira Jr., Silvio C.   +7 more
core   +1 more source

Oncolytic adenoviruses encoding bispecific T cell engagers or a novel trispecific T cell engager for dual-targeting of c-MET and EGFR

Molecular Therapy: Oncology
This study reports a strategy to overcome immune escape of tumors during viro-immunotherapy due to tumor heterogeneity. We pursued a dual-targeting approach of epidermal growth factor receptor (EGFR) and cellular mesenchymal epithelial transition factor (
Martin A. Boos, Oliver Seifert, Stefanie Sawall, Jessica Genz, Annika Huber, Ilse Hofmann, Roland E. Kontermann, Guy Ungerechts, Dirk M. Nettelbeck   +8 more
doaj   +1 more source

Dynamics of an HIV-1 Virotherapy Model

, 2019
In this project, we extend the work done this summer on the dynamics of an HIV-1 virotherapy model. We now consider a model with six equations, disregarding the number of free HIV virions in the system.
McBride, Mary
core   +1 more source

Virotherapy for Breast Cancer

, 2016
Breast cancer (BrCa) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. Current therapies for BrCa are insufficient to cure metastatic disease and are often associated with debilitating side effects that severely
Chaurasiya, Shyambabu
core   +1 more source

Comparative safety and efficacy of oncolytic virotherapy for the treatment of individuals with malignancies: a systematic review, meta-analysis, and Bayesian network meta-analysisResearch in context

EClinicalMedicine
Summary: Background: Oncolytic virotherapy (OV) is an innovative immunotherapy strategy. A comprehensive understanding of oncolytic viruses is essential for advancing research and clinical practice.
Poyee Lau, Long Liang, Xiang Chen, Jianglin Zhang, Hong Liu   +4 more
doaj   +1 more source

Current Development of Virotherapy in Breast Cancer: A Brief Review

Acta Medica Bulgarica
Breast cancer is the cancer with the greatest incidence in the world by 2020. This cancer has a high mortality rate, has the capability of metastasizing, and causes damage to important organs of the human body.
Sasmana I., Putri P., Dewi N., Supadmanaba I., Wihandani D.   +4 more
doaj   +1 more source