Results 81 to 90 of about 10,988 (206)
American Journal of Ophthalmology Case Reports, 2020 Purpose: To describe a case of choroidal melanoma treated with Rigvir® virotherapy in an adjuvant setting. Observations: A female patient born in 1956 presented with a small choroidal melanoma in October 2007. 34 months after transpupillary thermotherapy
Inta Jaunalksne +4 more
doaj +1 more source
Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy
MedComm, Volume 7, Issue 8, August 2026.Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge +5 more
wiley +1 more source
Oncolytic viruses encoding bispecific T cell engagers: a blueprint for emerging immunovirotherapies
Journal of Hematology & Oncology, 2021 Bispecific T cell engagers (BiTEs) are an innovative class of immunotherapeutics that redirect T cells to tumor surface antigens. While efficacious against certain hematological malignancies, limited bioavailability and severe toxicities have so far ...
Johannes P. W. Heidbuechel +1 more
doaj +1 more source
Emerging Immune‐Based Therapeutic Strategies in Hepatocellular Carcinoma
Liver International, Volume 46, Issue 8, August 2026.ABSTRACT Hepatocellular carcinoma (HCC) remains a leading cause of cancer‐related mortality worldwide despite recent advances in systemic therapy. The introduction of immune checkpoint inhibitors has substantially expanded treatment options for advanced disease; however, durable responses are observed only in a subset of patients.
Janine Kah +2 more
wiley +1 more source
Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks
Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan +8 more
wiley +1 more source
Macrophage delivered oncolytic virotherapy in triple negative breast cancer [PDF]
Background: Triple negative breast cancer (TNBC) is a high cause of morbidity and mortality. Novel treatments for TNBC are needed to extend the overall survival of patients with metastatic TNBC where the prognosis remains poor.
Kwan, Amy
core +4 more sources
Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy
Advanced Science, Volume 13, Issue 40, 17 July 2026.ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang +10 more
wiley +1 more source
Perbandingan waktu kestabilan model virotherapy dan radiovirotherapy untuk penyakit tumor [PDF]
, 2012 Tumor merupakan penyakit yang diakibatkan oleh pertumbuhan sel atau jaringan tubuh yang tidak normal. Penyakit tumor menjadi ancaman serius terhadap kesehatan manusia, banyak orang yang meninggal akibat penyakit tersebut.
Riswandi, Mila Kurnia
core +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 7, July 2026.Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Targeting oncogenic fusion-driven NUT carcinoma with CRISPR-Cas9 genome editing
Molecular Therapy: OncologyNUT carcinoma (NC) is a highly aggressive malignancy characterized by an oncogenic fusion gene incorporating the NUTM1 gene. To date, no established treatment options exist.
Maxim F. Carle +7 more
doaj +1 more source