Results 61 to 70 of about 7,822 (173)
Advanced Science, Volume 13, Issue 35, 24 June 2026.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Cancer Cell International, 2022 Viruses are completely dependent on host cell machinery for their reproduction. As a result, factors that influence the state of cells, such as signaling pathways and gene expression, could determine the outcome of viral pathogenicity.
Sara Shayan +2 more
doaj +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, Volume 13, Issue 35, 24 June 2026.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
American Journal of Ophthalmology Case Reports, 2020 Purpose: To describe a case of choroidal melanoma treated with Rigvir® virotherapy in an adjuvant setting. Observations: A female patient born in 1956 presented with a small choroidal melanoma in October 2007. 34 months after transpupillary thermotherapy
Inta Jaunalksne +4 more
doaj +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Aggregate, Volume 7, Issue 6, June 2026.Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
Oncolytic viruses encoding bispecific T cell engagers: a blueprint for emerging immunovirotherapies
Journal of Hematology & Oncology, 2021 Bispecific T cell engagers (BiTEs) are an innovative class of immunotherapeutics that redirect T cells to tumor surface antigens. While efficacious against certain hematological malignancies, limited bioavailability and severe toxicities have so far ...
Johannes P. W. Heidbuechel +1 more
doaj +1 more source
Immunogenic Cell Death: Unlocking New Frontiers in Cancer Immunotherapy
Cancer Innovation, Volume 5, Issue 3, June 2026.Immunogenic cell death ICD is a specific type of stress‐induced cell death that results in adaptive immune response and generating an immunological memory. The development of strategies that induce ICD are considered highly effective in the treatment of cancer within the bounds of immunotherapy.
Katherine Yaacoub
wiley +1 more source
Inducible CRISPR/Cas systems in precision oncology: Current applications and future perspectives
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.Inducible CRISPR/Cas systems enable spatiotemporal genome editing in precision oncology. Chemical, optical, physical, and microenvironmental stimuli provide distinct control strategies. Conditional activation may reduce off‐target exposure and basal nuclease activity.
Ziliang Ding +3 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.Immune cells infected by therapeutic poxviruses release increased amounts of extracellular vesicles bearing viral proteins and therapeutic payloads. Such EVs have the ability to activate a CD8+ T‐cell mediated antitumoral immune response and decrease tumor growth.
Lucas Walther +12 more
wiley +1 more source