Results 61 to 70 of about 13,638 (219)

Targeting Gene-Virotherapy for Cancer [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2005
Gene therapy and viral therapy for cancer have therapeutic effects, but there has been no significant breakthrough in these two forms of therapy. Therefore, a new strategy called "targeting gene-virotherapy", which combines the advantages of gene therapy and viral therapy, has been formulated. This new therapy has stronger antitumor effects than either
Xin-Yuan, Liu   +2 more
openaire   +2 more sources

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang   +10 more
wiley   +1 more source

The role of viruses in cancer development versus cancer therapy: An oncological perspective

open access: yesCancer Medicine, 2023
Despite great medical advances, oncological research is still looking for novel therapeutic approaches due to the limitation of conventional therapeutic agents.
Hossein Javid   +7 more
doaj   +1 more source

Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis

open access: yes, 2018
Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects.
Eladdadi, Amina   +4 more
core   +1 more source

Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs [PDF]

open access: yes, 2017
BACKGROUND: Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation.
Arafat WO   +16 more
core   +2 more sources

Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks

open access: yesChemistry – A European Journal, EarlyView.
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan   +8 more
wiley   +1 more source

Oncolytic virotherapy and the current approaches in veterinary medicine

open access: yesGerman Journal of Veterinary Research, 2022
Cancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment.
Bengu Bilgic, Banu Dokuzeylul, Mehmet Or
doaj   +1 more source

Cytolytic replication of echoviruses in colon cancer cell lines [PDF]

open access: yes, 2011
Background Colorectal cancer is one of the most common cancers in the world, killing nearly 50% of patients afflicted. Though progress is being made within surgery and other complementary treatments, there is still need for new and more effective ...
Stina Israelsson   +3 more
core   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

High Level Production of Monoclonal Antibodies Using an Optimized Plant Expression System

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Biopharmaceuticals are a large and fast-growing sector of the total pharmaceutical market with antibody-based therapeutics accounting for over 100 billion USD in sales yearly.
Andrew G. Diamos   +16 more
doaj   +1 more source

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