Results 51 to 60 of about 10,988 (206)
Viruses, 2017 Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells.
Masmudur M. Rahman, Grant McFadden
doaj +1 more source
Gene and virotherapy for hematological malignancies [PDF]
International Journal of Hematology, 2016 Recent years have seen a transformation in the treatment of hematological malignancies. Advances in gene therapy and molecular techniques and significant gains in computational abilities have supported the rapid development of safer and better tolerated therapies for many patients with hematologic cancers.
Evidio, Domingo-Musibay +1 more
openaire +2 more sources
Progress of oncolytic virotherapy for neuroblastoma
Frontiers in Pediatrics, 2022 As a neuroendocrine tumor derived from the neural crest, neuroblastoma (NB) is the most common extracranial solid tumor in children. The prognosis in patients with low- and intermediate-risk NB is favorable while that in high-risk patients is often detrimental.
Xiao-Tong Chen +7 more
openaire +3 more sources
Enhancing oncolytic virotherapy: Observations from a Voronoi Cell-Based model [PDF]
, 2020 Oncolytic virotherapy is a promising cancer treatment using genetically modified viruses. Unfortunately, virus particles rapidly decay inside the body, significantly hindering their efficacy.
Kim, PS +3 more
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PathogensCutaneous T-cell lymphoma (CTCL) is a devastating, potentially fatal T-lymphocyte malignancy affecting the skin. Despite all efforts, the etiology of this disease remains unknown.
Assia Angelova +2 more
doaj +1 more source
The role of viruses in cancer development versus cancer therapy: An oncological perspective
Cancer Medicine, 2023 Despite great medical advances, oncological research is still looking for novel therapeutic approaches due to the limitation of conventional therapeutic agents.
Hossein Javid +7 more
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Advanced Science, EarlyView.Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang +14 more
wiley +1 more source
Oncolytic virotherapy - analysis, design, models [PDF]
The deliberate use of viruses as oncolytic (cancer killing) agents has become evident since initial observations tracing back to the early 20th century. However, clinical use of therapeutic viruses requires them to be safe and effective.
Bhatt, Darshak; id_orcid, Bhatt, Darshak
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Molecular Circuits of Immune Sensing and Response to Oncolytic Virotherapy [PDF]
Oncolytic virotherapy is a promising immunotherapy approach for cancer treatment, utilizing viruses to preferentially infect and eliminate cancer cells while stimulating immune responses.
Daemen, Toos; id_orcid +1 more
core +2 more sources
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
Advanced Science, EarlyView.A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source