Results 51 to 60 of about 11,979 (257)
Personalizing Oncolytic Virotherapy?
raditionally, cancer therapies have been based on the empiric discovery of drugs and/or biological agents that act selectively against tumor cells. Recently, however, a generation of rationally discov-ered drugs and agents has been developed that shows encouraging benefi t in treating cancers.
E. Antonio Chiocca, Balveen Kaur
openaire +3 more sources
Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells.
Masmudur M. Rahman, Grant McFadden
doaj +1 more source
Modeling dynamics of cancer virotherapy with immune response
Virotherapy is a therapeutic treatment for cancer. It uses genetically engineered viruses to selectively infect, replicate in, and destroy cancer cells without damaging normal cells.
Salma M. Al-Tuwairqi+2 more
doaj +1 more source
Glioblastoma microenvironment and its reprogramming by oncolytic virotherapy
Glioblastoma (GBM), a highly aggressive form of brain tumor, responds poorly to current conventional therapies, including surgery, radiation therapy, and systemic chemotherapy.
Zhongbing Qi+3 more
semanticscholar +1 more source
Intracranial Virotherapy for a Canine Hemangioma
Intracranial hemangiomas are rare neoplastic lesions in dogs that usually appear with life-threatening symptoms. The treatment of choice is tumor resection; however, complete resection is rarely achieved. The patient’s prognosis therefore usually worsens due to tumor progression, and adjuvant treatments are required to control the disease.
Pablo Delgado-Bonet+6 more
openaire +2 more sources
The role of viruses in cancer development versus cancer therapy: An oncological perspective
Despite great medical advances, oncological research is still looking for novel therapeutic approaches due to the limitation of conventional therapeutic agents.
Hossein Javid+7 more
doaj +1 more source
NUT (nuclear-protein-in-testis) carcinoma (NC) is a highly aggressive tumor disease. Given that current treatment regimens offer a median survival of six months only, it is likely that this type of tumor requires an extended multimodal treatment approach
Stavros Sotiriadis+5 more
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Melanoma is considered an aggressive malignancy with a tendency of forming metastasis in the brain. Less than 10% of all melanoma cases present with unknown primary tumor location.
Guna Proboka+5 more
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Oncolytic Virotherapy: A New Paradigm in Cancer Immunotherapy
Oncolytic viruses (OVs) are emerging as potential treatment options for cancer. Natural and genetically engineered viruses exhibit various antitumor mechanisms.
S. Volovat+12 more
semanticscholar +1 more source
Oncolytic Virotherapy for Cancer: Clinical Experience
Oncolytic viruses are a new class of therapeutics which are largely in the experimental stage, with just one virus approved by the FDA thus far. While the concept of oncolytic virotherapy is not new, advancements in the fields of molecular biology and ...
S. Chaurasiya, Y. Fong, S. Warner
semanticscholar +1 more source