Results 51 to 60 of about 11,979 (257)

Personalizing Oncolytic Virotherapy?

open access: yesMolecular Therapy, 2007
raditionally, cancer therapies have been based on the empiric discovery of drugs and/or biological agents that act selectively against tumor cells. Recently, however, a generation of rationally discov-ered drugs and agents has been developed that shows encouraging benefi t in treating cancers.
E. Antonio Chiocca, Balveen Kaur
openaire   +3 more sources

Myxoma Virus dsRNA Binding Protein M029  Inhibits the Type I IFN‐Induced Antiviral State in a  Highly Species‐Specific Fashion

open access: yesViruses, 2017
Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader  cellular host range in cultured cells.
Masmudur M. Rahman, Grant McFadden
doaj   +1 more source

Modeling dynamics of cancer virotherapy with immune response

open access: yesAdvances in Difference Equations, 2020
Virotherapy is a therapeutic treatment for cancer. It uses genetically engineered viruses to selectively infect, replicate in, and destroy cancer cells without damaging normal cells.
Salma M. Al-Tuwairqi   +2 more
doaj   +1 more source

Glioblastoma microenvironment and its reprogramming by oncolytic virotherapy

open access: yesFrontiers in Cellular Neuroscience, 2022
Glioblastoma (GBM), a highly aggressive form of brain tumor, responds poorly to current conventional therapies, including surgery, radiation therapy, and systemic chemotherapy.
Zhongbing Qi   +3 more
semanticscholar   +1 more source

Intracranial Virotherapy for a Canine Hemangioma

open access: yesInternational Journal of Molecular Sciences, 2022
Intracranial hemangiomas are rare neoplastic lesions in dogs that usually appear with life-threatening symptoms. The treatment of choice is tumor resection; however, complete resection is rarely achieved. The patient’s prognosis therefore usually worsens due to tumor progression, and adjuvant treatments are required to control the disease.
Pablo Delgado-Bonet   +6 more
openaire   +2 more sources

The role of viruses in cancer development versus cancer therapy: An oncological perspective

open access: yesCancer Medicine, 2023
Despite great medical advances, oncological research is still looking for novel therapeutic approaches due to the limitation of conventional therapeutic agents.
Hossein Javid   +7 more
doaj   +1 more source

Multimodal Therapy Approaches for NUT Carcinoma by Dual Combination of Oncolytic Virus Talimogene Laherparepvec with Small Molecule Inhibitors

open access: yesViruses
NUT (nuclear-protein-in-testis) carcinoma (NC) is a highly aggressive tumor disease. Given that current treatment regimens offer a median survival of six months only, it is likely that this type of tumor requires an extended multimodal treatment approach
Stavros Sotiriadis   +5 more
doaj   +1 more source

Melanoma Unknown Primary Brain Metastasis Treatment with ECHO-7 Oncolytic Virus Rigvir: A Case Report

open access: yesFrontiers in Oncology, 2018
Melanoma is considered an aggressive malignancy with a tendency of forming metastasis in the brain. Less than 10% of all melanoma cases present with unknown primary tumor location.
Guna Proboka   +5 more
doaj   +1 more source

Oncolytic Virotherapy: A New Paradigm in Cancer Immunotherapy

open access: yesInternational Journal of Molecular Sciences
Oncolytic viruses (OVs) are emerging as potential treatment options for cancer. Natural and genetically engineered viruses exhibit various antitumor mechanisms.
S. Volovat   +12 more
semanticscholar   +1 more source

Oncolytic Virotherapy for Cancer: Clinical Experience

open access: yesBiomedicines, 2021
Oncolytic viruses are a new class of therapeutics which are largely in the experimental stage, with just one virus approved by the FDA thus far. While the concept of oncolytic virotherapy is not new, advancements in the fields of molecular biology and ...
S. Chaurasiya, Y. Fong, S. Warner
semanticscholar   +1 more source

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