Results 61 to 70 of about 13,459 (185)
PathogensCutaneous T-cell lymphoma (CTCL) is a devastating, potentially fatal T-lymphocyte malignancy affecting the skin. Despite all efforts, the etiology of this disease remains unknown.
Assia Angelova +2 more
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Viruses, 2017 Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells.
Masmudur M. Rahman, Grant McFadden
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Oncolytic Adenovirus-Induced Autophagy: Tumor-Suppressive Effect and Molecular Basis [PDF]
, 2013 Autophagy is a catabolic process that produces energy through lysosomal degradation of intracellular organelles. Autophagy functions as a cytoprotective factor under physiological conditions such as nutrient deprivation, hypoxia, and interruption of ...
Fujiwara, Toshiyoshi +2 more
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Targeting Gene-Virotherapy for Cancer [PDF]
Acta Biochimica et Biophysica Sinica, 2005 Gene therapy and viral therapy for cancer have therapeutic effects, but there has been no significant breakthrough in these two forms of therapy. Therefore, a new strategy called "targeting gene-virotherapy", which combines the advantages of gene therapy and viral therapy, has been formulated. This new therapy has stronger antitumor effects than either
Xin-Yuan, Liu +2 more
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Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion [PDF]
, 2017 Paediatric high grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are invasive tumours with poor survival. Oncolytic virotherapy, initially devised as a direct cytotoxic treatment, is now also known to act via immune-mediated mechanisms ...
Bartolini +38 more
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The role of viruses in cancer development versus cancer therapy: An oncological perspective
Cancer Medicine, 2023 Despite great medical advances, oncological research is still looking for novel therapeutic approaches due to the limitation of conventional therapeutic agents.
Hossein Javid +7 more
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Oncolytic virotherapy and the current approaches in veterinary medicine
German Journal of Veterinary Research, 2022 Cancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment.
Bengu Bilgic, Banu Dokuzeylul, Mehmet Or
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A genetically modified adenoviral vector with a phage display-derived peptide incorporated into fiber fibritin chimera prolongs survival in experimental glioma [PDF]
, 2015 The dismal clinical context of advanced-grade glioma demands the development of novel therapeutic strategies with direct patient impact. Adenovirus-mediated virotherapy represents a potentially effective approach for glioma therapy.
Ahmed, Atique U +12 more
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Syncytia Formation in Oncolytic Virotherapy [PDF]
Molecular Therapy - Oncolytics, 2019 Oncolytic virotherapy uses replication-competent virus as a means of treating cancer. Whereas this field has shown great promise as a viable treatment method, the limited spread of these viruses throughout the tumor microenvironment remains a major challenge. To overcome this issue, researchers have begun looking at syncytia formation as a novel method
Chase Burton, Eric Bartee
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High Level Production of Monoclonal Antibodies Using an Optimized Plant Expression System
Frontiers in Bioengineering and Biotechnology, 2020 Biopharmaceuticals are a large and fast-growing sector of the total pharmaceutical market with antibody-based therapeutics accounting for over 100 billion USD in sales yearly.
Andrew G. Diamos +16 more
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