Results 61 to 70 of about 17,431 (301)
Viruses, 2017 Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells.
Masmudur M. Rahman, Grant McFadden
doaj +1 more source
Modeling dynamics of cancer virotherapy with immune response
Advances in Difference Equations, 2020 Virotherapy is a therapeutic treatment for cancer. It uses genetically engineered viruses to selectively infect, replicate in, and destroy cancer cells without damaging normal cells.
Salma M. Al-Tuwairqi +2 more
doaj +1 more source
Uncovering a novel mechanism whereby NK cells interfere with glioblastoma virotherapy [PDF]
, 2014 Despite initial promising results, the success of clinical trials testing oncolytic viruses in glioblastoma patients has been limited. Innate immunity appears to be one among several barriers against successful viral oncolysis.
Alvarez-Breckenridge, Christopher A. +3 more
core +1 more source
Oncolytic Virotherapy in Peritoneal Metastasis Gastric Cancer: The Challenges and Achievements
Frontiers in Molecular Biosciences, 2022 Gastric cancer (GC) is the fourth most common cancer and the second leading cause of cancer death globally. Although the mortality rate in some parts of the world, such as East Asia, is still high, new treatments and lifestyle changes have effectively ...
S. Shao +7 more
semanticscholar +1 more source
CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter [PDF]
, 2016 Ad vectors are promising delivery vehicles for cancer therapeutic interventions. However, their application is limited by promiscuous tissue tropism and hepatotoxicity. This limitation can be avoided by altering the native tropism of Ads so that they can
Bhatia, Shilpa +4 more
core +3 more sources
The role of viruses in cancer development versus cancer therapy: An oncological perspective
Cancer Medicine, 2023 Despite great medical advances, oncological research is still looking for novel therapeutic approaches due to the limitation of conventional therapeutic agents.
Hossein Javid +7 more
doaj +1 more source
Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis
, 2018 Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects.
Eladdadi, Amina +4 more
core +1 more source
Current Approaches for Glioma Gene Therapy and Virotherapy
Frontiers in Molecular Neuroscience, 2021 Glioblastoma (GBM) is the most common and aggressive primary brain tumor in the adult population and it carries a dismal prognosis. Inefficient drug delivery across the blood brain barrier (BBB), an immunosuppressive tumor microenvironment (TME) and ...
K. Banerjee +13 more
semanticscholar +1 more source
VirusesNUT (nuclear-protein-in-testis) carcinoma (NC) is a highly aggressive tumor disease. Given that current treatment regimens offer a median survival of six months only, it is likely that this type of tumor requires an extended multimodal treatment approach
Stavros Sotiriadis +5 more
doaj +1 more source
Frontiers in Oncology, 2018 Melanoma is considered an aggressive malignancy with a tendency of forming metastasis in the brain. Less than 10% of all melanoma cases present with unknown primary tumor location.
Guna Proboka +5 more
doaj +1 more source