Results 81 to 90 of about 13,459 (185)
Targeting gene-virotherapy of cancer [PDF]
Cell Research, 2006 Our purpose is to completely elimination of xenograft tumor in animal tumor model in order to work out a protocal for the cure of patient. Gene therapy and viral therapy for cancer have got some therapeutic effects, but both have no great breakthrough.
Xin Yuan, Liu, Jin Fa, Gu
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Rational engineering of microRNA-regulated viruses for cancer gene therapy [PDF]
, 2013 MicroRNAs (miRNAs) are small noncoding RNA molecules that have important regulatory roles in a wide range of biological processes. miRNAs are often expressed in a tissue- and/or differentiation state-specific patterns, and it is estimated that miRNAs can
Ylösmäki, Erkko
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Oncolytic virotherapy for pancreatic cancer [PDF]
Expert Reviews in Molecular Medicine, 2011 Within the past decade, many oncolytic viruses (OVs) have been studied as potential treatments for pancreatic cancer and some of these are currently under clinical trials. The applicability of certain OVs, such as adenoviruses, herpesviruses and reoviruses, for the treatment of pancreatic cancer has been intensively studied for several years, whereas ...
Sonia, Wennier +2 more
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Cancer Cell International, 2022 Viruses are completely dependent on host cell machinery for their reproduction. As a result, factors that influence the state of cells, such as signaling pathways and gene expression, could determine the outcome of viral pathogenicity.
Sara Shayan +2 more
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Immunotherapeutic potential of oncolytic vaccinia virus [PDF]
, 2014 The concept of oncolytic viral therapy was based on the hypothesis that engineering tumor-selectivity into the replication potential of viruses would permit direct destruction of tumor cells as a result of viral-mediated lysis, resulting in amplification
Thorne, SH
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A Dynamical Analysis on a Tumour Virotherapy Model with Standard Incident Rate [PDF]
, 2017 This paper discusses a dynamical analysis on a model that governs the growth of tumour cell under a therapy by using oncolytic viruses, on the standard incident rate.
Ikawati, D. S. (Deasy) +2 more
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An evaluation of the efficacy of adenovirus-mediated gene therapy with p53 for the treatment of cancer [PDF]
, 2015 Cancer is the second leading cause of mortality in the United States today, and equally prevalent throughout the world. Traditional treatments such as chemotherapy and radiotherapy have thus far proven unable to treat the disease with high efficacy, with
Liepart IV, George Hampson
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Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice [PDF]
, 2008 BACKGROUND: The NV1020 oncolytic herpes simplex virus type-1 has shown significant promise for the treatment of many different types of tumors in experimental animal models and human trials. Previously, we described the construction and use of the NV1020-
Israyelyan, Anna +5 more
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Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy [PDF]
, 2016 Ovarian cancer accounts for >140 000 deaths globally each year. Typically, disease is asymptomatic until an advanced, incurable stage. Although response to cytotoxic chemotherapy is frequently observed, resistance to conventional platinum-based therapies
A Hemminki +40 more
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Virotherapy in Head and Neck Cancer
Oral Oncology ReportsHead and neck cancer, comprising a diverse group of malignancies, presents significant challenges in terms of treatment efficacy and patient outcomes.
Zhan Wang
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