Results 81 to 90 of about 11,979 (257)
Cancer Cell International, 2022 Viruses are completely dependent on host cell machinery for their reproduction. As a result, factors that influence the state of cells, such as signaling pathways and gene expression, could determine the outcome of viral pathogenicity.
Sara Shayan +2 more
doaj +1 more source
Cancer Innovation, Volume 4, Issue 4, August 2025.Glioblastoma (GBM) remains a highly malignant brain tumor with limited treatment efficacy, driving the need for innovative cellular immune theranostic strategies that integrate diagnostic and therapeutic approaches. Recent advances in cellular immunotherapy for GBM include chimeric antigen receptor (CAR)‐T/NK cells, macrophage‐based therapies ...
Ying Gong +14 more
wiley +1 more source
Oncolyic Virotherapy for Prostate Cancer: Lighting a Fire in Winter
International Journal of Molecular Sciences, 2022 As the most common cancer of the genitourinary system, prostate cancer (PCa) is a global men′s health problem whose treatments are an urgent research issue.
Gongwei Wang +4 more
semanticscholar +1 more source
Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms
Frontiers in Cardiovascular Medicine, 2021 The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine protease cascades are critical determinants of morbidity and mortality during infection and with vascular or tissue injury. Both the clot forming (thrombotic) and the
Jordan R. Yaron +6 more
doaj +1 more source
The Role of PIWI‐Interacting RNA in Urologic Carcinoma and Its Clinical Implications
Cancer Reports, Volume 8, Issue 8, August 2025.ABSTRACT Piwi‐interacting RNA (piRNA) represents a class of small non‐coding RNA molecules, typically ranging in length from 18 to 35 nucleotides. These molecules are critically involved in the preservation of genomic integrity and the regulation of protein translation processes.
Jiajia Cai +9 more
wiley +1 more source
Oncolytic Virotherapy in Solid Tumors: The Challenges and Achievements
Cancers, 2021 Simple Summary Oncolytic virotherapy (OVT) is a promising approach in cancer immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without in-depth knowledge of tumor antigens.
Ke-Tao Jin +5 more
semanticscholar +1 more source
Oncolytic polio virotherapy of cancer [PDF]
Cancer, 2014 Recently, the century‐old idea of targeting cancer with viruses (oncolytic viruses) has come of age, and promise has been documented in early stage and several late‐stage clinical trials in a variety of cancers. Although originally prized for their direct tumor cytotoxicity (oncolytic virotherapy), recently, the proinflammatory and immunogenic effects ...
John H. Sampson +12 more
openaire +3 more sources
AIMS Biophysics, 2023 In this paper, a biophysical fractional diffusive cancer model with virotherapy is thoroughly analyzed and analytically simulated. The goal of this biophysical model is to represent both the dynamics of cancer development and the results of virotherapy ...
Mohammed Alabedalhadi +2 more
doaj +1 more source
High Cell Density Perfusion Process of Quail Cells Producing Oncolytic rVSV‐NDV
Engineering in Life Sciences, Volume 25, Issue 7, July 2025.ABSTRACT Oncolytic viruses as agents for the treatment of various types of cancer have demonstrated their potential in many clinical studies over the past decades. In particular, rVSV‐NDV (a recombinant vesicular stomatitis virus [VSV] construct with fusogenic Newcastle disease virus glycoproteins) shows promising preclinical results.
Lennart Jacobtorweihe +5 more
wiley +1 more source
Current strategies to circumvent the antiviral immunity to optimize cancer virotherapy
Journal for ImmunoTherapy of Cancer, 2021 Cancer virotherapy is a paradigm-shifting treatment modality based on virus-mediated oncolysis and subsequent antitumor immune responses. Clinical trials of currently available virotherapies showed that robust antitumor immunity characterizes the ...
D. Shin +6 more
semanticscholar +1 more source