Results 141 to 150 of about 4,403,980 (152)

VIRTUAL BIOEQUIVALENCE APPLICATIONS IN DRUGS

Objective: Virtual bioequivalence studies play a critical role in facilitating and optimizing drug development processes of new drugs and generic drugs. This approach relies on mathematical calculations to mimic and predict the behavior of drugs in the human body.
Gülsün, Tuğba, Demir, Huriye, Öner, Levent   +2 more
openaire   +1 more source

DISOPYRAMIDE PHOSPHATE AND BASE ARE ‘VIRTUALLY BIOEQUIVALENT’

InPharma, 1978
openaire   +1 more source

Conjunction of semi-mechanistic modeling and population pharmacokinetics as a tool for virtual bioequivalence analysis - a case study for a BCS class II drug

European Journal of Pharmaceutics and Biopharmaceutics, 2023
Dorota Danielak, Michał Romański, Marcela Staniszewska   +2 more
exaly  

Virtual Workshop Report: Approaches, Regulatory Challenges, and Advances in Bioequivalence, Dissolution Testing, and Biowaivers: Manila, Philippines, February 22-24, 2023

Dissolution Technologies, 2023
James E. Polli, Vivian A. Gray, Willison John E. De Luna, Andreas Abend, Michael Daniel C. Lucagbo, Sandra Suarez-Sharp, Alicia P. Catabay, Leonel Santos, Bienvenido S. Balotro   +8 more
openaire   +1 more source

Establishing virtual bioequivalence and clinically relevant specifications using biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. case example: Naproxen

European Journal of Pharmaceutical Sciences, 2020
Jennifer Dressman, Nikoletta Fotaki, Ioannis Loisios-Konstantinidis   +2 more
exaly  

In silico prediction of bioequivalence of Isosorbide Mononitrate tablets with different dissolution profiles using PBPK modeling and simulation

European Journal of Pharmaceutical Sciences, 2021
Zhou Zhou, Ji Jiang, Fan Zhang
exaly  

Integrated Pirana–Simcyp Virtual Bioequivalence converts PBPK simulations into rapid, reproducible, and extensible bioequivalence decisions

Craig, James, Morris, Natalie M., McNally, Kevin, Clairissa Corpstein, kRISHNA CHAITANYA Telaprolu, Bogdanovich, Pauline, Turner, David, Rostami-Hodjegan, Amin, Jamei, Masoud, Bois, Frederic Yves   +9 more
openaire   +1 more source

PBPK-Based Virtual Bioequivalence Trials to Guide Drug Development

Amitava Mitra, Jim Mullin, Siri Kalyan Chirumamilla   +2 more
openaire   +1 more source

Prediction of fasted and fed bioequivalence for immediate release drug products using physiologically based biopharmaceutics modeling (PBBM)

European Journal of Pharmaceutical Sciences, 2020
Jereb Rebeka, Albin Kristl
exaly  

P.6.4 DEVELOPMENT OF A GENERATIVE ARTIFICIAL INTELLIGENCE ALGORITHM FOR THE REGENERATION OF VIRTUAL VOLUNTEERS IN BIOEQUIVALENCE STUDIES

Physica Medica
A. Nikolopoulos, V. Karalis
openaire   +1 more source