Results 121 to 130 of about 1,942 (154)

Challenges for switching central nervous system and psychiatric medication products: A review of the literature. [PDF]

J Psychopharmacol
Procyshyn RM, Katzman MA, Margolese HC, Agid O, Blier PM.   +4 more
europepmc   +1 more source

Exploring Tafamidis Effects Through PBPK-QSP Modelling. [PDF]

Pharmaceutics
Ulaszek S, Lisowski B, Wiśniowska B, Polak S.   +3 more
europepmc   +1 more source

High frequency deep brain stimulation of the hippocampus in a rat model for temporal lobe epilepsy [PDF]

, 2006
Boon, Paul, CLAEYS, P, De Smedt, Tim, Leybaert, Luc, Mabilde, Cyriel, Raedt, Robrecht, Van den broecke, Caroline, Wadman, Wytse, Waterschoot, Liesbeth, Wyckhuys, Tine   +9 more
core   +1 more source

Effect of Hepatic Impairment on Trofinetide Exposures Using an In Silico Physiologically Based Pharmacokinetic Model. [PDF]

Adv Ther
Darwish M, Obianom ON, Youakim JM, Darling I, Lukacova V, Bradley H.   +5 more
europepmc   +1 more source

Optimization of wet granulation process for manufacturing Rivaroxban generic immediate-release tablets using PBPK modeling and simulations. [PDF]

In Silico Pharmacol
Shiekmydeen J, Tanisha, Sharma S, Chakraborty K, Kannaiyan DC, Khan NA, Malayandi R.   +6 more
europepmc   +1 more source

In Silico Research Is Rewriting the Rules of Drug Development: Is It the End of Human Trials? [PDF]

Cureus
Lakhan SE.
europepmc   +1 more source

PBPK Modeling to Support Bioavailability and Bioequivalence Assessment in Pediatric Populations. [PDF]

Pharm Res
Wu F, Tsakalozou E, Burckart GJ, Žakelj R, Gaohua L, Sagawa K, Lukacova V, Vaithiyalingam S, Fan J, Fotaki N, Patel N, Fang L.   +11 more
europepmc   +1 more source

Clinical Laboratory Parameter-Driven Machine Learning for Participant Selection in Bioequivalence Studies Among Patients With Gastric Cancer: Framework Development and Validation Study. [PDF]

JMIR AI
Shon B, Seong SJ, Choi EJ, Gwon MR, Lee HW, Park J, Chung HY, Jeong S, Yoon YR.   +8 more
europepmc   +1 more source

Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and its Regulatory Utility to Support Oral Drug Product Development and Harmonization. [PDF]

Pharm Res
Cheng YH, Thomas S, Tsang YC, Almeida S, Ashraf M, Fotaki N, Heimbach T, Patel N, Shah H, Jiang X, Kim MJ, Moody R, Rostami-Hodjegan A, Singh R, Zhao L, Babiskin A, Wu F.   +16 more
europepmc   +1 more source

Effect of Obesity on the Exposure of Long-acting Cabotegravir and Rilpivirine: A Modeling Study. [PDF]

Clin Infect Dis
Bettonte S, Berton M, Stader F, Battegay M, Marzolini C.   +4 more
europepmc   +1 more source