Results 121 to 130 of about 4,403,980 (152)

Global Trends in Integrating Machine Learning (ML) with Model-Informed Drug Development (MIDD): A Bibliometric and Systematic Review (2015-2025). [PDF]

Pharmaceutics
Dermawan D, Chtita S, Alotaiq N.
europepmc   +1 more source

Model Ensembling and Machine Learning Approaches to Predict the First Dose of Amoxicillin in Intensive Care. [PDF]

CPT Pharmacometrics Syst Pharmacol
Leiwolf M, Gregoire N, Magréault S, Franck B, Krekounian O, Woillard JB, Aranzana-Climent V.   +6 more
europepmc   +1 more source

Training the next-generation of biomedical scientists through artificial intelligence-driven education and research in pharmacology and pharmaceutical sciences. [PDF]

Exp Biol Med (Maywood)
Kumar S, Karwasra R, Zhou W, Seetharaman J, Singla B.   +4 more
europepmc   +1 more source

Development of in vitro-in vivo correlation for establishing patient-centric quality standards of dissolution for lamotrigine extended-release tablets. [PDF]

Eur J Pharm Biopharm
Zidan A, Siddique AB, Shaklah M, Anand O, O'Connor T, Ashraf M.   +5 more
europepmc   +1 more source

Development of a Physiologically Based Biopharmaceutics Model Report Template: Considerations for Improved Quality in View of Regulatory Submissions. [PDF]

Mol Pharm
Arora S, Pepin X, Jamei M, Sharma P, Heimbach T, Wagner C, Bransford P, Kollipara S, Ahmed T, Hingle M, Dallmann A, Scherholz M, Stamatis SD, Cano-Vega M, Mistry N, Tannergren C, Borges L, Lindahl A, Rullo G, Mackie C, Mitra A, Kushner J, Harish Jain KM, Polli JE.   +23 more
europepmc   +1 more source

Mechanistic Modelling of Lidocaine and Prilocaine Absorption from EMLA Cream upon Topical Application using Physiologically Based Pharmacokinetic Modelling. [PDF]

AAPS PharmSciTech
Telaprolu KC, Tsakalozou E, Ghosh P, Alam K, Grice JE, Roberts MS, Jamei M, Polak S, Clarke JF.   +8 more
europepmc   +1 more source

Model-Informed Dosing Regimen of Sugemalimab for European Patients With Non-Small Cell Lung Cancer: Bridging From Asian Clinical Data. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sheng Y, Yue Z, Xu F, Wang K, Wang J, Shi Q.   +5 more
europepmc   +1 more source

Bioequivalence of alternative pembrolizumab dosing regimens: current practice and future perspectives. [PDF]

Cancer Commun (Lond)
Malmberg R, Agema BC, Hofman MM, Oosterveld S, Bins S, Dumoulin DW, Joosse A, Aerts JGJV, Debets R, Koch BCP, van der Veldt AAM, van Leeuwen RWF, Mathijssen RHJ.   +12 more
europepmc   +1 more source

Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria

Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria
openaire   +1 more source

Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria

European Journal of Pharmaceutical Sciences, 2017
Majority of bioequivalence studies are conducted in healthy volunteers. It has been argued that bioequivalence may not necessarily hold true in relevant patient populations due to a variety of reasons which affect one formulationmore than the other for ...
Adam S Darwich, Kosuke Doki, Nikunjkumar Patel   +2 more
exaly   +4 more sources