Results 91 to 100 of about 59,693 (314)
Advanced Science, EarlyView.TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin +11 more
wiley +1 more source
Ontology engineering in virtual breeding environments
, 2007 This paper proposes a new method for managing the use of ontologies in the context of a Virtual Breeding Environment. This research work focus is on the dissolution phase of a Virtual Enterprise or Collaborative Network, whereontology segmentation ...
Lucas Soares, António +9 more
core +1 more source
Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
Identifying the World Selected School Libraries’ Services in order to Provide a Proposal for Iran [PDF]
پژوهش در روشهای آموزشThis article aims to examine the services of selected school libraries in the world and to determine and prioritize the services proposed for Iranian school libraries.
Yaghob Norouzi +3 more
doaj +1 more source
UMSL Libraries - UMSL Virtual Showcase Video
, 2020 As part of the 2020 UMSL Virtual Showcase, the UMSL Libraries introduced themselves to prospective students over zoom.https://irl.umsl.edu/libpub/1041/thumbnail ...
University of Missouri-St. Louis Libraries
core
Advanced Science, EarlyView.This study establishes an interpretable machine learning framework that disentangles the intrinsic molecular efficacy of passivators from experimental platform effects—enabling unbiased, high‐throughput discovery of effective perovskite surface modifiers.
Jing Zhang +5 more
wiley +1 more source
Elektroniczne usługi informacyjne typu pytanie-odpowiedź - światowe trendy i doświadczenia bibliotek [PDF]
, 2006 The article presents various types of electronic (virtual, digital) reference services offered by libraries around the world, from the simplest ones e.g. e-mail to most advanced services such as interactive ones based on chat technology.
Derfert-Wolf, Lidia
core
Advanced Science, EarlyView.Cuttlebone‐inspired architected metamaterials introduce controlled structural disorder to simultaneously enhance strength, energy absorption, and compressive stability. Tunable disorder suppresses shear anisotropy, outperforms periodic lattices, and establishes discrete randomness as a robust route to high‐performance lightweight mechanical ...
Zengqin Shi +7 more
wiley +1 more source
Embedding Research and Learning in Libraries.
, 2006 The theme of this conference is “Embedding Libraries in Research and Learning.” While this is critical within the context of the new technologies and new service expectations of scholars and students it is also important that research and learning remain
Maes, William R
core
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source