Results 31 to 40 of about 350,314 (261)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Tobramycin and Amikacin Delay Adhesion and Microcolony Formation in Pseudomonas aeruginosa Cystic Fibrosis Isolates

Frontiers in Microbiology, 2017
Cystic fibrosis (CF) patients are predisposed to chronic colonization of the major airways by Pseudomonas aeruginosa biofilms. Pulmonary infections, involving sessile bacteria, are the main cause of morbidity and mortality.
Elodie Olivares, Elodie Olivares, Stéphanie Badel-Berchoux, Christian Provot, Benoît Jaulhac, Gilles Prévost, Thierry Bernardi, François Jehl   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Assessment of Borrelia miyamotoi in febrile patients and ticks in Alsace, an endemic area for Lyme borreliosis in France

Parasites & Vectors, 2020
Background Borrelia miyamotoi is a relapsing fever Borrelia species transmitted by ticks of the Ixodes ricinus complex. Human disease caused by B. miyamotoi was first described in Russia and later in the USA and Japan.
Pierre H. Boyer, Joris Koetsveld, Laurence Zilliox, Hein Sprong, Émilie Talagrand-Reboul, Yves Hansmann, Sylvie Josiane de Martino, Nathalie Boulanger, Joppe W. Hovius, Benoît Jaulhac   +9 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Epidemiological and genomic analysis of Acinetobacter baumannii strains from retailed raw meat

Heliyon
Acinetobacter baumannii causes hospital-acquired infections in human patients with compromised immune system. Strains associated to nosocomial infections are often resistant to carbapenems and belong to few international clones (IC1-11). A.
Leila Hamze, Raquel Garcia-Fierro, Antoine Drapeau, Pauline François, Andrea Endimiani, Jean-Yves Madec, Marisa Haenni, Vincent Perreten, Agnese Lupo   +8 more
doaj   +1 more source

Temporal dynamics of the fecal microbiota in veal calves in a 6-month field trial

Animal Microbiome, 2020
Background Little is known about maturation of calves’ gut microbiome in veal farms, in which animals are confined under intensive-farming conditions and the administration of collective antibiotic treatment in feed is common.
Méril Massot, Marisa Haenni, Thu Thuy Nguyen, Jean-Yves Madec, France Mentré, Erick Denamur   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comprehensive genomic analysis of antibiotic resistance plasmids in animal-associated Staphylococcus aureus in France

Microbiology Spectrum
In Staphylococcus aureus, an animal pathogen and zoonotic agent, plasmids play a pivotal role in the acquisition and spread of antibiotic resistance genes (ARGs). This study investigated the plasmid content of 329 S.
Rachel Contarin, Séverine Murri, Antoine Drapeau, Tom Cayssials, Jean-Yves Madec, Emilie Dordet-Frisoni, Marisa Haenni   +6 more
doaj   +1 more source

Pathogenic Escherichia coli in Dogs Reveals the Predominance of ST372 and the Human-Associated ST73 Extra-Intestinal Lineages

Frontiers in Microbiology, 2020
Escherichia coli is a ubiquitous commensal and pathogen that has also been recognized as a multi-sectoral indicator of antimicrobial resistance (AMR).
Charlotte Valat, Antoine Drapeau, Stéphanie Beurlet, Véronique Bachy, Henri-Jean Boulouis, Raphaëlle Pin, Géraldine Cazeau, Jean-Yves Madec, Marisa Haenni   +8 more
doaj   +1 more source