Results 61 to 70 of about 748,301 (348)

First Global Report of Plasmid-Mediated mcr-1 and Extended-Spectrum Beta-Lactamase-Producing Escherichia coli from Sheep in Portugal

Antibiotics, 2021
Resistances to extended-spectrum cephalosporins (ESC) and colistin are One Health issues since genes encoding these resistances can be transmitted between all sectors of the One Health concept, i.e., human, animal, and the environment.
Josman Dantas Palmeira, Marisa Haenni, Jean-Yves Madec, Helena Maria Neto Ferreira   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Anthropisation et maladies à tique : l’exemple de la borréliose de Lyme

Comptes Rendus Biologies, 2023
Ticks and tick-borne diseases are on the rise throughout the world. The reasons are multifactorial but all associated with human practices, including climate change and socio-economic and eco systemic changes. In the northern hemisphere, Lyme borreliosis
Boulanger, Nathalie
doaj   +1 more source

Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion. [PDF]

, 2019
Group A Streptococcus (GAS) is a human-specific pathogen that evades the host immune response through the elaboration of multiple virulence factors. Although many of these factors have been studied, numerous proteins encoded by the GAS genome are of ...
Campeau, Anaamika, Dehaini, Diana, Fang, Ronnie H, Gonzalez, David J, Greene, Trever, Holay, Maya, Lamsa, Anne, LaRock, Christopher N, Pogliano, Kit, Sands, Jenna S, Wei, Xiaoli, Wierzbicki, Igor H, Ying, Man, Zhang, Liangfang, Zuniga, Elina   +14 more
core  

Development of ListeriaBase and comparative analysis of Listeria monocytogenes [PDF]

, 2015
Background: Listeria consists of both pathogenic and non-pathogenic species. Reports of similarities between the genomic content between some pathogenic and non-pathogenic species necessitates the investigation of these species at the genomic level to ...
Ang, Mia Yang, Choo, Siew Woh, Dutta, Avirup, Heydari, Hamed, Mutha, Naresh VR, Siow, Cheuk Chuen, Tan, Mui Fern, Tan, Shi Yang, Wee, Wei Yee, Wong, Guat Jah   +9 more
core   +3 more sources

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Limitation of Screening of Different Variants of SARS-CoV-2 by RT-PCR

Diagnostics, 2021
Since January 2021, the diffusion of the most propagated SARS-CoV-2 variants in France (UK variant 20I/501Y.V1 (lineage B.1.1.7), 20H/H501Y.V2 (lineage B.1.351) and 20J/H501Y.V3 (lineage P.1)) were urgently screened, needing a surveillance with an RT-PCR
Agathe Boudet, Robin Stephan, Sophie Bravo, Milène Sasso, Jean-Philippe Lavigne   +4 more
doaj   +1 more source

Identification of the long polar fimbriae gene variants in the locus of enterocyte effacement-negative Shiga toxin-producing Escherichia coli strains isolated from humans and cattle in Argentina [PDF]

, 2010
The long polar fimbriae (Lpf) is one of few adhesive factors of Shiga toxin-producing Escherichia coli (STEC) and it is associated with colonization of the intestine. Studies have demonstrated the presence of lpf genes in several pathogenic E.
Galli, Lucía, Rivas, Marta, Torres, Alfredo G.   +2 more
core   +2 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

The interplay between mobilome and resistome in Staphylococcus aureus

mBio
Antibiotic resistance genes (ARGs) in Staphylococcus aureus can disseminate vertically through successful clones, but also horizontally through the transfer of genes conveyed by mobile genetic elements (MGEs).
Rachel Contarin, Antoine Drapeau, Pauline François, Jean-Yves Madec, Marisa Haenni, Emilie Dordet-Frisoni   +5 more
doaj   +1 more source