Results 91 to 100 of about 13,136,107 (398)

Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]

, 2013
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Bull, TJ, Greene, M, Linedale, R, McKendrick, IJ, Sales, J, Schock, A, Sharp, JM, Stevenson, K   +7 more
core   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Streptococcus mutans and Actinomyces naeslundii Interaction in Dual-Species Biofilm

Microorganisms, 2020
The study of bacterial interaction between Streptococcus mutans and Actinomyces naeslundii may disclose important features of biofilm interspecies relationships.
Rosa Virginia Dutra de Oliveira, Fernanda Salloume Sampaio Bonafé, Denise Madalena Palomari Spolidorio, Cristiane Yumi Koga-Ito, Aline Leite de Farias, Kelly R. Kirker, Garth A. James, Fernanda Lourenção Brighenti   +7 more
doaj   +1 more source

A combined approach for comparative exoproteome analysis of Corynebacterium pseudotuberculosis [PDF]

, 2011
Background: Bacterial exported proteins represent key components of the host-pathogen interplay. Hence, we sought to implement a combined approach for characterizing the entire exoproteome of the pathogenic bacterium Corynebacterium pseudotuberculosis,
Azevedo, Vasco, Carvalho, Maria A. R., Castro, Thiago L. P., Dowson, Christopher G., Farias, Luiz M., Meyer, Roberto, Miyoshi, Anderson, Oliveira, Sérgio C., Pacheco, Luis G. C., Pimenta, Adriano M. C., Santos, Agenor V., Santos, Anderson R., Santos, Simone G., Scrivens, James H., Seyffert, Núbia, Silva, Artur, Silva, Wanderson M., Slade, Susan E.   +17 more
core   +4 more sources

Virulence Factors of Sporothrix schenckii

Journal of Fungi, 2022
Sporothrix schenckii is one of the etiological agents of sporotrichosis. In this review, we discuss the virulence factors that have been proven to participate in the S. schenckii-host interaction. Among these known factors, we can find cell wall glycoproteins, adhesins, melanin, extracellular vesicles, and dimorphism.
Laura Cristina García-Carnero, José Ascención Martínez-Álvarez   +1 more
openaire   +3 more sources

Dual‐Layer Living Hydrogel Enables On‐Demand Delivery of Phages and Probiotics for Synergistic Wound Infection Therapy

Advanced Functional Materials, EarlyView.
A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao, Darine D'Adam, Anna Hu, Sixuan Zhang, Josua Roduner, Katharina Maniura‐Weber, Qun Ren   +6 more
wiley   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Salmonella enterica virulence databases and bioinformatic analysis tools development

Scientific Reports
Salmonella enterica, a prominent foodborne pathogen, contributes significantly to global foodborne illnesses annually. This species exhibits significant genetic diversity, potentially impacting its infectivity, disease severity, and antimicrobial ...
Jing Han, Hailin Tang, Shaohua Zhao, Steven L. Foley   +3 more
doaj   +1 more source

Genomic and Proteomic Analyses of Extracellular Products Reveal Major Virulence Factors Likely Accounting for Differences in Pathogenicity to Bivalves between Vibrio mediterranei Strains

Animals
Vibrio mediterranei, a bacterial pathogen of bivalves, has exhibited strain-dependent virulence. The mechanisms behind the variations in bivalve pathogenicity between V. mediterranei strains have remained unclear.
Congling Fan, Wenfang Dai, Haiyan Zhang, Sheng Liu, Zhihua Lin, Qinggang Xue   +5 more
doaj   +1 more source

The well-coordinated linkage between acidogenicity and aciduricity via insoluble glucans on the surface of Streptococcus mutans. [PDF]

, 2015
Streptococcus mutans is considered the principal cariogenic bacterium for dental caries. Despite the recognition of their importance for cariogenesis, the possible coordination among S.
Guo, Lihong, He, Xuesong, Lux, Renate, McLean, Jeffrey S, Shi, Wenyuan   +4 more
core   +1 more source