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Virulence factors of Entamoeba histolytica
Current Opinion in Microbiology, 1999Recent studies have increased our knowledge of Entamoeba histolytica cell biology and gene regulation. In the ameba, dominant-negative mutations in the Gal/GalNAc lectin affect adhesion and cytolysis, whereas mutations in meromyosin affect cytoskeletal function. Studying these mutant proteins has improved our understanding of the role of these proteins
C A, Gilchrist, W A, Petri
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Campylobacter virulence and survival factors
Food Microbiology, 2015Despite over 30 years of research, campylobacteriosis is the most prevalent foodborne bacterial infection in many countries including in the European Union and the United States of America. However, relatively little is known about the virulence factors in Campylobacter or how an apparently fragile organism can survive in the food chain, often with ...
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Virulence Factors in Pneumococcal Respiratory Pathogenesis
Future Microbiology, 2008Streptococcus pneumoniae (the pneumococcus) is a major global cause of human disease. Since the publication of the entire sequence of TIGR4 in 2001, our understanding of this human pathogen has increased significantly. Genetic studies, and the use of mutant strains have refined our understanding of the pathogenic mechanisms of classic pneumococcal ...
Preston, J. A., Dockrell, D. H.
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Virulence factors of Bordetella pertussis
Antonie van Leeuwenhoek, 1988Clearly, B. pertussis has evolved very elaborate mechanisms to maintain itself in the human host. Three different proteins (FHA, pertussis toxin and fimbriae) have been implicated in adherence. Furthermore, a number of toxins are produced (pertussis toxin, adenylate cyclase, dermonecrotic toxin, and tracheal cytotoxin) which destroy the clearance ...
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Virulence factors of Cryptococcus neoformans
Trends in Microbiology, 1995Cryptococcosis is a serious fungal disease in patients with AIDS or other defects in T-cell-mediated host defenses. Cryptococcus neoformans produces several virulence factors, most notably the polysaccharide capsule and phenol oxidase. Molecular studies of cryptococcal virulence factors have contributed to our understanding of the pathobiology of this ...
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VFDB 2022: a general classification scheme for bacterial virulence factors
Nucleic Acids Research, 2022Dandan Zheng, Lihong Chen, Jian Yang
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