Results 171 to 180 of about 398,884 (210)

Phage regulatory circuits and virulence gene expression

Current Opinion in Microbiology, 2005
In many pathogenic bacteria, genes that encode virulence factors are located in the genomes of prophages. Clearly bacteriophages are important vectors for disseminating virulence genes, but, in addition, do phage regulatory circuits contribute to expression of these genes?
Matthew K, Waldor, David I, Friedman
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Virulence Gene Expression: Fiat LuxO!

Science Signaling, 2002
Bacteria can monitor their population density through the perception of molecules secreted by other local bacteria. This phenomenon leads to changes in bacterial behavior and changes in gene expression, and is termed quorum sensing. Quorum sensing in Vibrio cholerae , a major pathogenic bacterium in ...
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DNA topology and bacterial virulence gene regulation

Trends in Microbiology, 1993
The topology of bacterial DNA varies in response to extracellular environmental stimuli, providing a possible mechanism for environmental control of gene expression during bacterial pathogenesis. The contribution of DNA topology to the control of transcription is complex, but an appreciation of the distinction between local and global DNA topological ...
C J, Dorman, N, Ní Bhriain
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Virulence gene regulation in vivo

Trends in Microbiology, 2001
Vibrio cholerae, the causative agent of epidemic cholera, must coordinate the expression of its virulence genes to produce disease. The most well defined virulence factors are the cholera toxin (CT) and the toxin co-regulated pilus (TCP), which are regulated by ToxR, TcpP and ToxT.
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CRISPR Gene Editing of Virulent Bacteriophage ICP1

Cold Spring Harbor Protocols, 2023
Tools for site-directed mutagenesis of virulent bacteriophages (phages; viruses of bacteria) have traditionally lagged those for bacteria, hindering their study. CRISPR gene editing represents a new and highly efficient method for editing virulent phage genomes.
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Virulence Gene Regulation in Escherichia coli

EcoSal Plus, 2006
Escherichia coli causes three types of illnesses in humans: diarrhea, urinary tract infections, and meningitis in newborns. The acquisition of virulence-associated genes and the ability to properly regulate these, often horizontally transferred, loci distinguishes pathogens from the normally harmless commensal E ...
Jay L, Mellies, Alex M S, Barron
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Defining Virulence Genes in the Dimorphic Fungi

Annual Review of Microbiology, 2006
Most dimorphic fungal pathogens cause respiratory disease in mammals and must therefore possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the past decade, advances in genetic tools have made it possible to investigate the basis of dimorphic fungal pathogenesis at the molecular level. Gene disruptions and RNA interference
Chad A, Rappleye, William E, Goldman
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[Virulence gene of H. pylori].

Nihon rinsho. Japanese journal of clinical medicine, 2001
H. pylori is a well-recognized pathogen that infects up to 50% of humans in the world. H. pylori lives for decades in the hostile environment of the human stomach. H. pylori is closely associated with histologic gastritis, gastric ulceration, duodenal ulceration, gastric cancer and MALT lymphoma.
T, Sugiyama, T, Mizushima, J, Ishizuka, M, Asaka   +3 more
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Agrobacterium virulence gene induction.

Methods in molecular biology (Clifton, N.J.), 2006
The ability of Agrobacterium to transform plants and other organisms is under highly regulated genetic control. Two Virulence (Vir) proteins, VirA and VirG, function as a two-component regulatory system to sense particular phenolic compounds synthesized by wounded plant tissues.
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Virulence gene regulation in Bordetella

2013
Bordetella species cause respiratory infections in mammals. Their master regulatory system BvgAS controls expression of at least three distinct phenotypic phases in response to environmental cues. The Bvg+ phase is necessary and sufficient for respiratory infection while the Bvg- phase is required for survival ex vivo.
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