Results 251 to 260 of about 2,134,385 (307)

The RNA-binding protein ProQ directly binds and regulates virulence genes in enterohemorrhagic Escherichia coli O157:H7. [PDF]

Front Cell Infect Microbiol
Qian Y, Zheng C, Han R.
europepmc   +1 more source

Isolation and Characterization of Vancomycin-Resistant <i>Enterococcus faecium</i> from Cattle: Antimicrobial Resistance, Virulence Genes, and Pathogenicity. [PDF]

Vet Sci
Cao M, Cao F, Wang C, Yan X, Dong F, Zhang S, Abousaad S, Yang L, Abouzeid AM, Wang Y, Qi Y.   +10 more
europepmc   +1 more source

Regulation of Virulence Gene Expression [PDF]

Virulence, 2014
The bacterial pathogen that finds itself, either by accident or design, within the human or animal host, senses and adapts to the prevailing conditions by modulating its gene expression on a global...
Sivaramesh Wigneshweraraj, Mark S Thomas
exaly   +4 more sources

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Virulence genes of poxviruses and reoviruses

Vaccine, 1988
Identification of viral genes that specify virulence, however defined, is of critical importance for the design of viral vaccines. In particular, the targeted development not only of avirulent vaccine strains but also of viruses to be used as carriers for foreign genes depends on the inactivation or deletion of genes that harm the host.
W K, Joklik, D J, Pickup, D D, Patel, M D, Moody   +3 more
openaire   +2 more sources

Virulence gene expression in vivo

Current Opinion in Microbiology, 2004
The ability to identify and isolate bacterial RNA from animals or humans with infections has markedly advanced the capacity to examine microbial gene expression in vivo. This advance has been coupled with the development of quantitative real-time reverse transcription polymerase chain reaction and expression microarrays to allow investigators to ...
Samuel A, Shelburne, James M, Musser
openaire   +2 more sources

In search of tuberculosis virulence genes

Trends in Microbiology, 1996
The identity of the virulence genes that enable tuberculosis organisms to survive in macrophages and to induce the features of tuberculosis remains largely unknown. Numerous putative virulence genes have been identified, but so far there is only conclusive evidence for the role of two genes, KatG and rpoV, in virulence.
openaire   +2 more sources

CRISPR Gene Editing of a Virulent Bacteriophage

Cold Spring Harbor Protocols, 2023
Genome editing by site-directed mutagenesis is an important tool in biological research. CRISPR gene editing is the latest such tool developed, and one that is widely applicable to study organisms from all kingdoms of life. Here, I introduce a method for making site-directed, defined mutations in a virulent bacteriophage (a bacterial virus) using ...
openaire   +2 more sources

Genes controlling retroviral virulence

1997
Publisher Summary Retroviruses under normal circumstances infect cells and yet inflict relatively little damage to the infected cell. The cell, however, remains infected for the lifespan of that cell or any daughter cells derived from that infected cell.
openaire   +2 more sources

Defining Virulence Genes in the Dimorphic Fungi

Annual Review of Microbiology, 2006
Most dimorphic fungal pathogens cause respiratory disease in mammals and must therefore possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the past decade, advances in genetic tools have made it possible to investigate the basis of dimorphic fungal pathogenesis at the molecular level. Gene disruptions and RNA interference
Chad A, Rappleye, William E, Goldman
openaire   +2 more sources