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Molecular analysis of spv virulence genes of the salmonella virulence plasmids
Molecular Microbiology, 1993SummaryGenes on an 8 kb region common to the virulence plasmids of several serovars of Salmonella are sufficient to replace the entire plasmid in enabling systemic infection in animal models. This virulence region encompasses five genes which previously have been designated with different names from each investigating laboratory.
P A, Gulig +5 more
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Virulence Gene Regulation in Shigella
EcoSal Plus, 2004Shigella species are the causative agents of bacillary dysentery in humans, an invasive disease in which the bacteria enter the cells of the epithelial layer of the large intestine, causing extensive tissue damage and inflammation. They rely on a plasmid-encoded type III secretion system (TTSS) to cause disease; this system and
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VIRULENCE GENES OFCLOSTRIDIUM PERFRINGENS
Annual Review of Microbiology, 1998▪ Abstract Clostridium perfringens causes human gas gangrene and food poisoning as well as several enterotoxemic diseases of animals. The organism is characterized by its ability to produce numerous extracellular toxins including α-toxin or phospholipase C, θ-toxin or perfringolysin O, κ-toxin or collagenase, as well as a sporulation-associated ...
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Expression of Virulence Genes in Candida Albicans
2005The analysis of virulence gene expression patterns during infection gives insights into regulatory adaptation mechanisms of microbial pathogens in various host niches.The establishment of an in vivo expression technology for C. albicans allows us to investigate at which stage of an infection virulence genes might play a role in the host-pathogen ...
P, Staib +4 more
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Mapping Arenavirus Genes Causing Virulence
1987The reassortment of genetic information from RNA viruses with segmented genomes, i. e., Arenaviridae, Bunyaviridae, Orthomyxoviridae, and Reoviridae families, can occur within cells infected by two different viral strains from the same family (COmpans etal. 1981; FIelds and GReene 1982; WEbster etal. 1982; Palese 1984).
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Virulence gene regulation in vivo
Trends in Microbiology, 2001Vibrio cholerae, the causative agent of epidemic cholera, must coordinate the expression of its virulence genes to produce disease. The most well defined virulence factors are the cholera toxin (CT) and the toxin co-regulated pilus (TCP), which are regulated by ToxR, TcpP and ToxT.
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The "Alien DNA" of Virulence Genes
Science, 1996Bacteria do a brisk trade in useful genes, swapping bits of DNA among themselves like baseball cards, and the recently discovered type III secretion genes are clearly foreign to the pathogens now using them. Researchers are still seeking the original source of these “alien” virulence genes.
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[Virulence gene of H. pylori].
Nihon rinsho. Japanese journal of clinical medicine, 2001H. pylori is a well-recognized pathogen that infects up to 50% of humans in the world. H. pylori lives for decades in the hostile environment of the human stomach. H. pylori is closely associated with histologic gastritis, gastric ulceration, duodenal ulceration, gastric cancer and MALT lymphoma.
T, Sugiyama +3 more
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Virulence gene regulation in Bordetella
2013Bordetella species cause respiratory infections in mammals. Their master regulatory system BvgAS controls expression of at least three distinct phenotypic phases in response to environmental cues. The Bvg+ phase is necessary and sufficient for respiratory infection while the Bvg- phase is required for survival ex vivo.
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[Virulence-related genes of Vibrio alginolyticus and its virulence in mice].
Wei sheng wu xue bao = Acta microbiologica Sinica, 2014We determinated the virulence factors of Vibrio alginolyticus strains isolated from the environment by multiplex PCRs and animal experiments, in order to compare the differences between the highly virulent strain and attenuated virulent strain, and to explore the virulent mechanism of V.
Pan, Xiong +6 more
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