Results 51 to 60 of about 268,142 (318)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Adherence to and Invasion of Human Intestinal Cells by Arcobacter Species and Their Virulence Genotypes

, 2013
The genus Arcobacter is composed of 17 species which have been isolated from various sources. Of particular interest are A. butzleri, A. cryaerophilus, and A.
Figueras, MJ, Alkeskas, A, Levican, A, Forsythe, SJ, Gunter, C   +4 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion [PDF]

, 2014
The ability of Salmonella to cause disease depends on metabolic activities and virulence factors. Here, we show that a key metabolic protein, EIIAGlc, is absolutely essential for acute infection, but not for Salmonella survival, in a mouse typhoid fever ...
Timo Glatter, Dirk Bumann,, Glatter, Timo, Glatter, T. ; https://orcid.org/, Mazé, Alain, Bumann, Dirk, Timo Glatter,, Dirk Bumann, Alain Mazé, Maze, A., Alain Mazé,, Bumann, D.   +11 more
core   +1 more source

Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model. [PDF]

PLoS Pathogens, 2012
Pseudomonas aeruginosa strain PA14 is an opportunistic human pathogen capable of infecting a wide range of organisms including the nematode Caenorhabditis elegans. We used a non-redundant transposon mutant library consisting of 5,850 clones corresponding
Rhonda L Feinbaum, Jonathan M Urbach, Nicole T Liberati, Slavica Djonovic, Allison Adonizio, Anne-Ruxandra Carvunis, Frederick M Ausubel   +6 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Distribution of virulence genes of foodborne Listeria monocytogenes in Liaoning Province, 2020—2021

Zhongguo shipin weisheng zazhi
ObjectiveTo analyze the distribution characteristics of virulence genes and drug resistance of foodborne Listeria monocytogenes （Lm） in Liaoning Province， 2020—2021.MethodsThe 19 virulence genes of Lm including 6 loci （prfA， plcA， plcB， hlyA， mpl and ...
SUN Tingting, WANG Weijie, LI Xue
doaj   +1 more source

Association of Virulence and Antibiotic Resistance in Salmonella—Statistical and Computational Insights into a Selected Set of Clinical Isolates

Microorganisms, 2020
The acquisition of antibiotic resistance (AR) by foodborne pathogens, such as Salmonella enterica, has emerged as a serious public health concern. The relationship between the two key survival mechanisms (i.e., antibiotic resistance and virulence) of ...
Daleniece Higgins, Nabanita Mukherjee, Chandan Pal, Irshad M. Sulaiman, Yu Jiang, Samir Hanna, John R. Dunn, Wilfried Karmaus, Pratik Banerjee   +8 more
doaj   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Virulence-associated genes detected by genome analysis.

, 2018
Virulence-associated genes detected by genome analysis.
Estelle Jumas-Bilak (54354), Brigitte Lamy (131457), Fadua Latif-Eugenín (5635019), Roxana Beaz-Hidalgo (685156), Sophie Colston (5635022), Maria-Jose Figueras (685157), Joerg Graf (229951), Emilie Talagrand-Reboul (5467292)   +7 more
core   +1 more source