Results 61 to 70 of about 1,788,404 (210)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Bacterial human virulence genes across diverse habitats as assessed by in silico analysis of environmental metagenomes

Frontiers in Microbiology, 2016
The occurrence and distribution of clinically relevant bacterial virulence genes across natural (non-human) environments is not well understood. We aimed to investigate the occurrence of homologues to bacterial human virulence genes in a variety of ...
Ditte Andreasen Søborg, Niels Bohse Hendriksen, Jan H. Christensen, Mogens Kilian, Niels Kroer   +4 more
doaj   +1 more source

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype [PDF]

, 2009
Whereas most nontyphoidal Salmonella (NTS) are associated with gastroenteritis, there has been a dramatic increase in reports of NTS-associated invasive disease in sub-Saharan Africa. Salmonella enterica serovar Typhimurium isolates are responsible for a
Clarke, L., Molyneux, M., Molyneux, Malcolm, MacLennan, CA, Molyneux, Malcom E., Gordon, M. A., Kariuki, Samuel, Cormican, M., Parkhill, J, Holt, Kathryn E., Thomson, N., Kingsley, Robert, Harris, D., Whitehead, Sally, Heyderman, R., Kariuki, S., Thomson, N. R., MacLennan, Calman A., Whitehead, S., Achtman, Mark, Sangal, V, Molyneux, ME, Msefula, CL, Sangal, V., Marsh, K., Holt, K. E., Kariuki, S, Thomson, Nicholas R., MacLennan, Calman, Clarke, L, Achtman, M., Gordon, Melita A., MacLennan, C. A., Holt, Kathryn, Gordon, M., Heyderman, R. S., Dougan, G., Gordon, Melita, Sangal, Vartul, Holt, K., Msefula, C., Msefula, Chisomo, Cormican, Martin, Holt, KE, Parkhill, J., Kingsley, R., Msefula, C. L., Msefula, Chisomo L., Marsh, K, Kingsley, RA, Kingsley, Robert A., Dougan, Gordon, Kingsley, R. A., Parkhill, Julian, Gordon, MA, Thomson, Nicholas, Whitehead, S, Harris, D, Molyneux, M. E., Heyderman, RS, Heyderman, Robert S., Harris, David, Marsh, Kevin, MacLennan, C., Clarke, Louise, Dougan, G, Heyderman, Robert, Thomson, NR, Achtman, M, Cormican, M   +69 more
core   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Virulence genes in Enterococcus faecium and Enterococcus faecalis isolated from blood culture in haematological patients [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. To study virulence genes in E. faecium and E. faecalis isolated from the blood cultures of patients with hematological diseases. Materials and Methods. Virulence genes were studied in E. faecium and E.
Fedorova A.V., Khrulnova S.A., Vetokhina A.V., Molchanova I.V., Kutsevalova O.Yu., Klyasova G.A.   +5 more
doaj   +1 more source

Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity

, 2010
Galleria mellonella (wax moth) larvae have elsewhere been shown to be susceptible to pathogens such as Francisella tularensis, Burkholderia mallei, and Pseudomonas aeruginosa.
Champion, O. L., Wren, B. W., Karlyshev, AV, Woodward, M, Senior, NJ, Wren, BW, Champion, OL, Howard, Sarah L, Titball, Richard W, Woodward, Martin J., Howard, SL, Wren, Brendan W, La Ragione, R., Titball, R. W., Champion, Olivia L, Senior, Nicola J, Senior, N. J., Howard, S. L., La Ragione, Roberto, La Ragione, R, Titball, RW, Karlyshev, Andrey V, Karlyshev, A. V., Woodward, Martin   +23 more
core   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

The impact of glycopeptide- and methicillin- resistance on "Staphylococcus aureus" and its virulence in localized and systemic infections [PDF]

, 2007
Adaptation of bacteria to their environment is a necessity to keep their fitness and survival under limiting conditions. In chapter I of this work we demonstrated that adaptation of glycopeptide-resistant S.
Karaüzüm, Hatice
core   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source