Results 61 to 70 of about 2,134,385 (307)

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype [PDF]

, 2009
Whereas most nontyphoidal Salmonella (NTS) are associated with gastroenteritis, there has been a dramatic increase in reports of NTS-associated invasive disease in sub-Saharan Africa. Salmonella enterica serovar Typhimurium isolates are responsible for a
Clarke, L., Molyneux, M., Molyneux, Malcolm, Gordon, M. A., Kariuki, Samuel, Cormican, M., Parkhill, J, Thomson, N., Kingsley, Robert, Harris, D., Whitehead, Sally, Heyderman, R., Kariuki, S., Thomson, N. R., Whitehead, S., Achtman, Mark, Sangal, V, Molyneux, ME, Msefula, CL, Sangal, V., Marsh, K., Holt, K. E., Kariuki, S, MacLennan, Calman, Clarke, L, Achtman, M., MacLennan, C. A., Holt, Kathryn, Gordon, M., Heyderman, R. S., Dougan, G., Gordon, Melita, Sangal, Vartul, Holt, K., Msefula, C., Msefula, Chisomo, Cormican, Martin, Holt, KE, Parkhill, J., Kingsley, R., Msefula, C. L., Marsh, K, Kingsley, RA, Dougan, Gordon, Kingsley, R. A., Parkhill, Julian, Gordon, MA, Thomson, Nicholas, Whitehead, S, Harris, D, Molyneux, M. E., Heyderman, RS, Harris, David, Marsh, Kevin, MacLennan, C., Clarke, Louise, Dougan, G, Heyderman, Robert, Thomson, NR, Achtman, M, Cormican, M   +60 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Correlation analysis of whole genome sequencing of a pathogenic Escherichia coli strain of Inner Mongolian origin

Scientific Reports
Anal swabs of 1-month-old Holstein calves with diarrhea were collected from an intensive cattle farm, and a highly pathogenic Escherichia coli strain was obtained by isolation and purification. To study the virulence and resistance genes of pathogenic E.
Yan Jia, Kai Zhang, Jinshan Cao, Wei Mao
doaj   +1 more source

Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity.

, 2010
Galleria mellonella (wax moth) larvae have elsewhere been shown to be susceptible to pathogens such as Francisella tularensis, Burkholderia mallei, and Pseudomonas aeruginosa.
Champion, O. L., Wren, B. W., Karlyshev, AV, Woodward, M, Senior, NJ, Wren, BW, Champion, OL, Howard, Sarah L, Titball, Richard W, Woodward, Martin J., Howard, SL, Wren, Brendan W, La Ragione, R., Titball, R. W., Champion, Olivia L, Senior, Nicola J, Senior, N. J., Howard, S. L., La Ragione, Roberto, La Ragione, R, Titball, RW, Karlyshev, Andrey V, Karlyshev, A. V., Woodward, Martin   +23 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Staphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated. [PDF]

, 2012
Staphylococcus aureus is a major cause of human and animal infections. Bacteriophage are a class of mobile genetic element (MGE) that carry virulence genes and disseminate them horizontally, including Panton-Valentine leukocidin (PVL), the immune evasion
McCarthy, AJ, Lindsay, JA, Alex J Mccarthy, Jodi A Lindsay, Witney, AA, Adam A Witney, Alex J. McCarthy, Jodi. A. Lindsay, Adam A. Witney   +8 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Regulation of virulence genes in Mycobacterium tuberculosis

International Journal of Medical Microbiology, 2001
Mycobacterium tuberculosis has demonstrated remarkable ability to survive in diverse conditions encountered during the infection process. These involve surviving the bactericidal stresses within the macrophage, the anaerobic and nutritionally altered environment of the granuloma, and the metabolically inactive latent state.
J, Mehrotra, W R, Bishai
openaire   +2 more sources

Evolution of linked avirulence effectors in Leptosphaeria maculans is affected by genomic environment and exposure to resistance genes in host plants [PDF]

, 2010
Brassica napus (canola) cultivars and isolates of the blackleg fungus, Leptosphaeria maculans interact in a ‘gene for gene’ manner whereby plant resistance (R) genes are complementary to pathogen avirulence (Avr) genes.
McDonald, B., Patrick C Brunner, Anton J Cozijnsen, Barbara J. Howlett, Cozijnsen, Anton J., Brunner, PC, van de Wouw, A.P., Howlett, B.J., Brunner, P., Howlett, BJ, Brunner Patrick C., McDonald, BA, James K. Hane, Oliver, R.P., Angela P Van de Wouw, Richard P. Oliver, Hane, James K., Howlett, Barbara J., Brunner, Patrick C., Oliver, Richard P., Richard P Oliver, Bruce A. McDonald, Angela P. Van de Wouw, Hane, JK, Oliver Richard P., Bruce A McDonald, Anton J. Cozijnsen, Brunner, P.C., Cozijnsen, AJ, Howlett, B., Hane, J., Hane James K., Hane, J.K., Barbara J Howlett, McDonald, Bruce A., van de Wouw, AP, Cozijnsen, A., James K Hane, Cozijnsen Anton J., Howlett Barbara J., McDonald Bruce A., Oliver, Richard, McDonald, B.A., Van de Wouw Angela P., Van de Wouw, Angela P., Patrick C. Brunner, Cozijnsen, A.J., Van de Wouw, A., Oliver, RP   +48 more
core   +1 more source

Study of virulence genes in vancomycin resistant Enterococci (vre) from animals and human clinical isolates | IJB

, 2021
With Enterococcus species as the leading cause of nosocomial infections and resistance to an array of antibiotics, this study focused to determine the frequency and distribution of vancomycin-resistant Enterococci, the presence of virulence genes, and ...
Pius Abimbola Okiki, Adeola Egbebi, Bondira Olamide Ndagana, Mofoluwaso Adedeji Oyinloye   +3 more
core   +1 more source