Results 81 to 90 of about 5,329,833 (353)

Detection of virulence genes, phylogenetic group and antibiotic resistance of uropathogenic Escherichia coli in Mongolia.

Journal of Infection in Developing Countries, 2017
INTRODUCTION The severity of urinary tract infection (UTI) produced by uropathogenic Escherichia coli (UPEC) is due to the expression of a wide spectrum of virulence genes. E.
Yandag Munkhdelger, Nyamaa Gunregjav, A. Dorjpurev, Nishi Juniichiro, J. Sarantuya   +4 more
semanticscholar   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Distribution of virulence genes of foodborne Listeria monocytogenes in Liaoning Province, 2020—2021

Zhongguo shipin weisheng zazhi
ObjectiveTo analyze the distribution characteristics of virulence genes and drug resistance of foodborne Listeria monocytogenes （Lm） in Liaoning Province， 2020—2021.MethodsThe 19 virulence genes of Lm including 6 loci （prfA， plcA， plcB， hlyA， mpl and ...
SUN Tingting, WANG Weijie, LI Xue
doaj   +1 more source

Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model. [PDF]

PLoS Pathogens, 2012
Pseudomonas aeruginosa strain PA14 is an opportunistic human pathogen capable of infecting a wide range of organisms including the nematode Caenorhabditis elegans. We used a non-redundant transposon mutant library consisting of 5,850 clones corresponding
Rhonda L Feinbaum, Jonathan M Urbach, Nicole T Liberati, Slavica Djonovic, Allison Adonizio, Anne-Ruxandra Carvunis, Frederick M Ausubel   +6 more
doaj   +1 more source

Epistatic control of intrinsic resistance by virulence genes in Listeria

PLoS Genetics, 2018
Elucidating the relationships between antimicrobial resistance and virulence is key to understanding the evolution and population dynamics of resistant pathogens. Here, we show that the susceptibility of the gram-positive bacterium Listeria monocytogenes
M. Scortti, Lei Han, S. Alvarez, A. Leclercq, A. Moura, Marc Lecuit, J. Vázquez-Boland   +6 more
semanticscholar   +1 more source

Heterochromatin‐mediated control of virulence gene expression [PDF]

Molecular Microbiology, 2006
SummaryIn recent years, the sequencing and annotation of complete genomes, together with the development of genetic and proteomic techniques to study previously intractable eukaryotic microbes, has revealed interesting new themes in the control of virulence gene expression.
Catherine J, Merrick, Manoj T, Duraisingh   +1 more
openaire   +2 more sources

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Prevalence, Virulence Genes and Antimicrobial Resistance Profiles of Salmonella Serovars from Retail Beef in Selangor, Malaysia

Frontiers in Microbiology, 2018
The aim of the present study was to investigate the prevalence of Salmonella spp., Salmonella Enteritidis and Salmonella Typhimurium in retail beef from different retail markets of Selangor area, as well as, to assess their pathogenic potential and ...
T. Thung, S. Radu, N. Mahyudin, Y. Rukayadi, Z. Zakaria, N. Mazlan, Boon-Huan Tan, Epeng Lee, Soo L. Yeoh, Y. Chin, C. Tan, C. Kuan, D. F. Basri, C. W. J. Wan Mohamed Radzi   +13 more
semanticscholar   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

Association of Virulence and Antibiotic Resistance in Salmonella—Statistical and Computational Insights into a Selected Set of Clinical Isolates

Microorganisms, 2020
The acquisition of antibiotic resistance (AR) by foodborne pathogens, such as Salmonella enterica, has emerged as a serious public health concern. The relationship between the two key survival mechanisms (i.e., antibiotic resistance and virulence) of ...
Daleniece Higgins, Nabanita Mukherjee, Chandan Pal, Irshad M. Sulaiman, Yu Jiang, Samir Hanna, John R. Dunn, Wilfried Karmaus, Pratik Banerjee   +8 more
doaj   +1 more source