Results 71 to 80 of about 379,610 (192)

Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. [PDF]

open access: yes, 2008
BACKGROUND: Human and animal health is constantly under threat by emerging pathogens that have recently acquired genetic determinants that enhance their survival, transmissibility and virulence.
Oyston, Petra C. F.   +38 more
core   +1 more source

Transcriptional adaptation of shigella flexneri during infection of macrophages and epithelial cells : insights into the strategies of a cytosolic bacterial pathogen [PDF]

open access: yes, 2005
Shigella flexneri, the etiologic agent of bacillary dysentery, invades epithelial cells as well as macrophages and dendritic cells and escapes into the cytosol soon after invasion.
Lucchini, Sacha   +4 more
core   +4 more sources

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2 [PDF]

open access: yes, 2002
In the present study we investigated the role of the fibronectin (FN)- and fibrinogen (FGN)-binding protein (FBPS) in the pathogenesis of Streptococcus suis serotype 2 in piglets. The complete gene encoding FBPS from S.
Dijkstra, J.   +11 more
core   +1 more source

New virulence-associated plasmid in Yersinia enterocolitica [PDF]

open access: yesJournal of Clinical Microbiology, 1982
In a study of 103 strains of Yersinia enterocolitica, 10 strains were found to be lethal for mice and to possess 42- and 82-megadalton plasmids. This association was statistically significant (P much less than 0.001). Serotypes of Y. enterocolitica previously considered avirulent were found to possess these plasmids and to be lethal for mice.
B A, Kay, K, Wachsmuth, P, Gemski
openaire   +2 more sources

The toxic guardians — multiple toxin-antitoxin systems provide stability, avoid deletions and maintain virulence genes of Pseudomonas syringae virulence plasmids

open access: yesMobile DNA, 2019
Background Pseudomonas syringae is a γ-proteobacterium causing economically relevant diseases in practically all cultivated plants. Most isolates of this pathogen contain native plasmids collectively carrying many pathogenicity and virulence genes ...
Leire Bardaji   +4 more
doaj   +1 more source

A Klebsiella variicola Plasmid Confers Hypermucoviscosity-Like Phenotype and Alters Capsule Production and Virulence

open access: yesFrontiers in Microbiology, 2020
Hypermucoviscosity (hmv) is a capsule-associated phenotype usually linked with hypervirulent Klebsiella pneumoniae strains. The key components of this phenotype are the RmpADC proteins contained in non-transmissible plasmids identified and studied in K ...
Nadia Rodríguez-Medina   +10 more
doaj   +1 more source

Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive Chlamydia trachomatis Biovars

open access: yesmBio, 2018
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes blinding trachoma and sexually transmitted disease. C. trachomatis isolates are classified into 2 biovars—lymphogranuloma venereum (LGV) and trachoma—which are ...
Michael John Patton   +12 more
doaj   +1 more source

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development [PDF]

open access: yes, 2011
Rhodococcus equi causes fatal pyogranulomatous pneumonia in foals and immunocompromised animals and humans. Despite its importance, there is currently no effective vaccine against the disease. The actinobacteria R.
Hessels G. I.   +25 more
core   +3 more sources

Virulence region of plasmid pNL2001 of Salmonella enteritidis [PDF]

open access: yesMicrobiology, 1994
The virulence region of the Salmonella enteritidis 55 kb plasmid pNL2001 was identified by Tn1-insertion mutagenesis, DNA hybridization studies, and Western blot analysis of proteins encoded in the virulence region of the plasmid. DNA hybridization studies showed that the pNL2001 plasmid contained a 6.4 kb SalI-EcoRI fragment homologous to the 6.4 kb ...
S, Suzuki   +9 more
openaire   +2 more sources

Molecular characterization of hybrid virulence plasmids in ST11-KL64 KPC-2-producing multidrug-resistant hypervirulent Klebsiella pneumoniae from China

open access: yesFrontiers in Microbiology
IntroductionCarbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) strains combining virulence and multidrug resistance (MDR) features pose a great public health concern. The aim of this study is to explore the evolutionary characteristics of
Fushan Zhang   +21 more
doaj   +1 more source

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