Results 51 to 60 of about 379,610 (192)

Hybrid Plasmids Encoding Antimicrobial Resistance and Virulence Traits Among Hypervirulent Klebsiella pneumoniae ST2096 in India

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundHypervirulent variants of Klebsiella pneumoniae (HvKp) were typically associated with a broadly antimicrobial susceptible clone of sequence type (ST) 23 at the time of its emergence.
Chaitra Shankar, Karthick Vasudevan, Jobin John Jacob, Stephen Baker, Barney J. Isaac, Ayyan Raj Neeravi, Dhiviya Prabaa Muthuirulandi Sethuvel, Biju George, Balaji Veeraraghavan   +8 more
doaj   +1 more source

Acquisition of a novel conjugative multidrug‐resistant hypervirulent plasmid leads to hypervirulence in clinical carbapenem‐resistant Klebsiella pneumoniae strains

mLife, 2023
The co‐occurrence of plasmid‐mediated multidrug resistance and hypervirulence in epidemic carbapenem‐resistant Klebsiella pneumoniae has emerged as a global public health issue. In this study, an ST23 carbapenem‐resistant hypervirulent K.
Gong Li, Ling Jia, Lei Wan, Lijuan Xia, Ang Gao, Runshi Yang, Ruanyang Sun, Minge Wang, Juan Du, Xinlei Lian, Rongmin Zhang, Liangxing Fang, Xiaoping Liao, Yahong Liu, Bao‐Tao Liu, Jian Sun   +15 more
doaj   +1 more source

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype [PDF]

, 2009
Whereas most nontyphoidal Salmonella (NTS) are associated with gastroenteritis, there has been a dramatic increase in reports of NTS-associated invasive disease in sub-Saharan Africa. Salmonella enterica serovar Typhimurium isolates are responsible for a
Clarke, L., Molyneux, M., Molyneux, Malcolm, MacLennan, CA, Molyneux, Malcom E., Gordon, M. A., Kariuki, Samuel, Cormican, M., Parkhill, J, Holt, Kathryn E., Thomson, N., Kingsley, Robert, Harris, D., Whitehead, Sally, Heyderman, R., Kariuki, S., Thomson, N. R., MacLennan, Calman A., Whitehead, S., Achtman, Mark, Sangal, V, Molyneux, ME, Msefula, CL, Sangal, V., Marsh, K., Holt, K. E., Kariuki, S, Thomson, Nicholas R., MacLennan, Calman, Clarke, L, Achtman, M., Gordon, Melita A., MacLennan, C. A., Holt, Kathryn, Gordon, M., Heyderman, R. S., Dougan, G., Gordon, Melita, Sangal, Vartul, Holt, K., Msefula, C., Msefula, Chisomo, Cormican, Martin, Holt, KE, Parkhill, J., Kingsley, R., Msefula, C. L., Msefula, Chisomo L., Marsh, K, Kingsley, RA, Kingsley, Robert A., Dougan, Gordon, Kingsley, R. A., Parkhill, Julian, Gordon, MA, Thomson, Nicholas, Whitehead, S, Harris, D, Molyneux, M. E., Heyderman, RS, Heyderman, Robert S., Harris, David, Marsh, Kevin, MacLennan, C., Clarke, Louise, Dougan, G, Heyderman, Robert, Thomson, NR, Achtman, M, Cormican, M   +69 more
core   +1 more source

The dynamic evolution and IS26-mediated interspecies transfer of a blaNDM-1-bearing fusion plasmid leading to a hypervirulent carbapenem-resistant Klebsiella pneumoniae strain harbouring blaKPC-2 in a single patient

Journal of Global Antimicrobial Resistance, 2023
: Objectives: To characterize the evolution and interspecies transfer of plasmids between Klebsiella pneumoniae and Escherichia coli within a single patient.
Yapei Zhang, Xuebin Tian, Fanghua Fan, Xuan Wang, Shilei Dong   +4 more
doaj   +1 more source

A hybrid plasmid formed by recombination of a virulence plasmid and a resistance plasmid in Klebsiella pneumoniae

Journal of Global Antimicrobial Resistance, 2020
The emergence of multidrug-resistant (MDR) and hypervirulent Klebsiella pneumoniae (hvKP) facilitates simultaneous dissemination of virulence and resistance in a single event, which poses serious threat to public health.This study characterized the multidrug-resistant and moderately virulent ST11 K64 K.
Xie, MM, Dong, N, Chen, KC, Yang, XM, Ye, LW, Chan, EWC, Zhang, R, Chen, S   +7 more
openaire   +4 more sources

Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans [PDF]

, 2013
BACKGROUND: Mycolactones are a family of polyketide-derived macrolide exotoxins produced by Mycobacterium ulcerans, the causative agent of the chronic necrotizing skin disease Buruli ulcer.
Gerd Pluschke, Claudio Bomio, Philipp Gersbach, Scherr, Nicole, Jun Li, Claudio Bomio (396151), Nicole Scherr, Karl-Heinz Altmann, Jean-Pierre Dangy (42481), Gersbach, Philipp, Gersbach Philipp, Dangy Jean-Pierre, Jean-Pierre Dangy, Jun Li (6494), Pluschke Gerd, Li Jun, Bomio Claudio, Altmann, Karl-Heinz, Gerd Pluschke (7855), Philipp Gersbach (396150), Li, Jun, Scherr Nicole, Karl-Heinz Altmann (396152), Bomio, Claudio, Altmann Karl-Heinz, Pluschke, Gerd, Dangy, Jean-Pierre, Nicole Scherr (396149)   +27 more
core   +2 more sources

Stabilization of the virulence plasmid pSLT of Salmonella Typhimurium by three maintenance systems and its evaluation by using a new stability test

Frontiers in Molecular Biosciences, 2016
Certain Salmonella enterica serovars belonging to subspecies I carry low-copy-number virulence plasmids of variable size (50-90 kb). All of these plasmids share the spv operon, which is important for systemic infection.
Damián Lobato-Márquez, Laura Molina-García, Inma Moreno-Córdoba, Francisco García-del Portillo, Ramón Díaz-Orejas   +4 more
doaj   +1 more source

The Identification, Isolation and Partial Characterisation of VapA-encoding virulence plasmids in Rhodococcus equi found in New Zealand. [PDF]

, 2010
This thesis describes the identification, isolation and partial characterisation of VapA-encoded virulence plasmids present in Rhodococcus equi (R. equi) found in foals in New Zealand. R.
Singh, Niharika
core  

Heterologous expression from Agrobacterium virulence promoters [PDF]

, 1991
The aim of this work was twofold: to construct plasmids with a gene encoding a pesticidal protein expressed from an Agrobacterium tumefaciens virulence promoter and to determine, in planta, the sites of Agrobacterium vir-induction.
Lilley, Catherine Jane, Lilley, C.J
core  

Cytokine profile in in vitro mouse macrophage culture infected with Bacillus anthracis spores with varying plasmid composition

Инфекция и иммунитет, 2022
Bacillus anthracis, the causative agent of anthrax, is able to exist both in environmental conditions (soil) and in the macroorganism. The manifestation of pathogenic properties of B.
Elena A. Koteneva, O. I. Tsygankova, V. Yu. Shcherbakova, A. V. Kalinin, I. S. Rodionov, V. V. Serdyukov, A. V. Abramovich, A. N. Kulichenko   +7 more
doaj   +1 more source