Results 31 to 40 of about 104,714 (231)

Virulence Plasmids of the Pathogenic Clostridia

Microbiology Spectrum, 2019
ABSTRACT The clostridia cause a spectrum of diseases in humans and animals ranging from life-threatening tetanus and botulism, uterine infections, histotoxic infections and enteric diseases, including antibiotic-associated diarrhea, and food poisoning.
Sarah A, Revitt-Mills, Callum J, Vidor, Thomas D, Watts, Dena, Lyras, Julian I, Rood, Vicki, Adams   +5 more
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Yersinia virulence: more than a plasmid [PDF]

FEMS Microbiology Letters, 2001
The genus Yersinia is composed of 11 species, three of which are pathogenic in humans. The three pathogens, Y. pestis, Y. enterocolitica, and Y. pseudotuberculosis, cause a broad spectrum of disease ranging from pneumonic plague to acute gastroenteritis.
P A, Revell, V L, Miller
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Virulence-associated plasmids in Rhodococcus equi [PDF]

Journal of Clinical Microbiology, 1993
Twenty-three strains of Rhodococcus equi from independent clinical cases were analyzed for the presence of virulence plasmid DNA. Of the clinical isolates, 19 contained an 85-kb plasmid and the remaining 4 contained a 90-kb plasmid. All of the isolates expressed 15- to 17-kDa antigens and were virulent in mice.
S, Takai, Y, Watanabe, T, Ikeda, T, Ozawa, S, Matsukura, Y, Tamada, S, Tsubaki, T, Sekizaki   +7 more
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A rare carbapenem-resistant hypervirulent K1/ST1265 Klebsiella pneumoniae with an untypeable blaKPC-harboured conjugative plasmid

Journal of Global Antimicrobial Resistance, 2020
Objective: We investigated the pathogenesis of a patient with severe acute pancreatitis by comprehensively analysing a rare carbapenem-resistant hypervirulent K1/ST1265 Klebsiella pneumoniae (CR-HvKP) strain. Methods: We conducted virulence and multidrug-
Cuidan Li, Guannan Ma, Tingting Yang, Xiaoyu Wen, Chuan Qin, Liya Yue, Xinmiao Jia, Yicheng Shen, Dandan Lu, Lifeng Wang, Dingxia Shen, Fei Chen   +11 more
doaj   +1 more source

Plasmid-associated virulence of Salmonella typhimurium [PDF]

Infection and Immunity, 1987
We investigated the role of the 100-kilobase (kb) plasmid of Salmonella typhimurium in the virulence of this organism for mice. Three strains, LT2-Z, SR-11, and SL1344, which possessed 100-kb plasmids with identical restriction enzyme digestion profiles, were cured of their respective 100-kb plasmids after Tnmini-tet was used to label plasmids.
P A, Gulig, R, Curtiss
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The Virulence Plasmid ofYersinia, an Antihost Genome [PDF]

Microbiology and Molecular Biology Reviews, 1998
SUMMARYThe 70-kb virulence plasmid enables Yersinia spp. (Yersinia pestis, Y. pseudotuberculosis, and Y. enterocolitica) to survive and multiply in the lymphoid tissues of their host. It encodes the Yop virulon, an integrated system allowing extracellular bacteria to disarm the cells involved in the immune response, to disrupt their communications, or ...
Cornelis, G. R., Boland, A., Boyd, A. P., Geuijen, C., Iriarte, M., Neyt, C., Sory, M. P., Stainier, I.   +7 more
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Plasmid maintenance functions of the large virulence plasmid of Shigella flexneri [PDF]

Journal of Bacteriology, 1997
The large virulence plasmid pMYSH6000 of Shigella flexneri contains a replicon and a plasmid maintenance stability determinant (Stb) on adjacent SalI fragments. The presence of a RepFIIA replicon on the SalI C fragment was confirmed, and the complete sequence of the adjacent SalI O fragment was determined. It shows homology to part of the transfer (tra)
L, Radnedge, M A, Davis, B, Youngren, S J, Austin   +3 more
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Mobilizable plasmids drive the spread of antimicrobial resistance genes and virulence genes in Klebsiella pneumoniae

Genome Medicine, 2023
Background Klebsiella pneumoniae is a notorious clinical pathogen and frequently carries various plasmids, which are the main carriers of antimicrobial resistance and virulence genes.
Jianfeng Zhang, Yanping Xu, Meng Wang, Xiaobin Li, Zhiyuan Liu, Dai Kuang, Zixin Deng, Hong-Yu Ou, Jieming Qu   +8 more
doaj   +1 more source

Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence [PDF]

Infection and Immunity, 1981
Virulent form I Shigella sonnei strains contain a 120-megadalton plasmid that is absent in their form II derivatives, which are always avirulent and devoid of O side chains. In the present study, 165 biochemical and antibiotic traits were assessed, but no experimentally useful phenotype could be associated with this large form I plasmid. Therefore, the
P J, Sansonetti, D J, Kopecko, S B, Formal   +2 more
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Identification of MrtAB, an ABC transporter specifically required for Yersinia pseudotuberculosis to colonize the mesenteric lymph nodes. [PDF]

PLoS Pathogens, 2012
A highly conserved virulence plasmid encoding a type III secretion system is shared by the three Yersinia species most pathogenic for mammals. Although factors encoded on this plasmid enhance the ability of Yersinia to thrive in their mammalian hosts ...
Gregory T Crimmins, Sina Mohammadi, Erin R Green, Molly A Bergman, Ralph R Isberg, Joan Mecsas   +5 more
doaj   +1 more source