Prevalence of Carbapenem-Resistant Klebsiella pneumoniae Co-Harboring blaKPC-Carrying Plasmid and pLVPK-Like Virulence Plasmid in Bloodstream Infections [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 This study aimed to characterize carbapenem-resistant Klebsiella pneumoniae (CR-KP) co-harboring blaKPC-2-carrying plasmid and pLVPK-like virulence plasmid.
Fang-ling Du +8 more
doaj +4 more sources
RES-Xre toxin-antitoxin locus knaAT maintains the stability of the virulence plasmid in Klebsiella pneumoniae [PDF]
Emerging Microbes and InfectionsHypervirulent Klebsiella pneumoniae isolates have been increasingly reported worldwide, especially hypervirulent drug-resistant variants owing to the acquisition of a mobilizable virulence plasmid by a carbapenem-resistant strain.
Yongkui Chen +7 more
doaj +2 more sources
The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria. [PDF]
PLoS PathogensMany species of pathogenic bacteria harbor critical plasmid-encoded virulence factors, and yet the regulation of plasmid replication is often poorly understood despite playing a key role in plasmid-encoded gene expression.
Katherine Schubert +17 more
doaj +2 more sources
Salmonella virulence plasmid: pathogenesis and ecology [PDF]
Pathogens and Disease, 2017 A current view on the role of the Salmonella virulence plasmid in the pathogenesis of animal and human hosts is discussed; including the possible relevance in secondary ecological niches. Various strategies towards further studies in this respect are proposed within the One Health Concept.
Claudia, Silva +2 more
openaire +4 more sources
Genetic Characterization of ExPEC-Like Virulence Plasmids among a Subset of NMEC. [PDF]
PLoS ONE, 2016 Neonatal Meningitis Escherichia coli (NMEC) is one of the most common causes of neonatal bacterial meningitis in the US and elsewhere resulting in mortality or neurologic deficits in survivors.
Bryon A Nicholson +7 more
doaj +3 more sources
The distribution of plasmids that carry virulence and resistance genes in Staphylococcus aureus is lineage associated. [PDF]
, 2012 BACKGROUND: Staphylococcus aureus is major human and animal pathogen. Plasmids often carry resistance genes and virulence genes that can disseminate through S. aureus populations by horizontal gene transfer (HGT) mechanisms. Sequences of S.
Lindsay, JA, McCarthy, AJ
core +4 more sources
Tracking Recombination Events That Occur in Conjugative Virulence Plasmid p15WZ-82_Vir during the Transmission Process [PDF]
mSystems, 2020 We recently reported the recovery of a conjugative virulence plasmid, p15WZ-82_Vir, from a clinical Klebsiella variicola strain. In this study, we found that several new plasmid types were generated due to genetic rearrangement.
Xuemei Yang +4 more
doaj +2 more sources
Colicin V virulence plasmids [PDF]
Microbiological Reviews, 1991 ColV plasmids are a heterogeneous group of IncFI plasmids which encode virulence-related properties such as the aerobactin iron uptake system, increased serum survival, and resistance to phagocytosis. These plasmids have been found in invasive strains of Escherichia coli which infect vertebrate hosts including humans and livestock.
V L Waters, Jorge H. Crosa
openalex +3 more sources
Co-occurrence of OXA-232, RmtF-encoding plasmids, and pLVPK-like virulence plasmid contributed to the generation of ST15-KL112 hypervirulent multidrug-resistant Klebsiella pneumoniae [PDF]
Frontiers in Microbiology, 2023 The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) strains and restricted therapeutic options pose a global threat to public health. Aminoglycosides are a wise choice, which can effectively reduce the mortality rate when combined with β ...
Chunyang Wu +12 more
doaj +2 more sources
Transmission of pLVPK-like virulence plasmid in Klebsiella pneumoniae mediated by an Incl1 conjugative helper plasmid [PDF]
iScience, 2022 Summary: We previously reported the recovery of five ST11 carbapenem resistant hypervirulent Klebsiella pneumoniae (CR-HvKP) strains that harbored pLVPK-like virulence plasmids, yet molecular mechanisms underlying acquisition of virulence plasmid by ST11
Xuemei Yang +8 more
doaj +2 more sources