Zika virus outbreak on Yap Island, Federated States of Micronesia.
New England Journal of Medicine, 2009 BACKGROUND In 2007, physicians on Yap Island reported an outbreak of illness characterized by rash, conjunctivitis, and arthralgia. Although serum from some patients had IgM antibody against dengue virus, the illness seemed clinically distinct from ...
Mark R. Duffy +19 more
semanticscholar +1 more source
Zika Virus and Birth Defects--Reviewing the Evidence for Causality.
New England Journal of Medicine, 2016 Summary The Zika virus has spread rapidly in the Americas since its first identification in Brazil in early 2015. Prenatal Zika virus infection has been linked to adverse pregnancy and birth outcomes, most notably microcephaly and other serious brain ...
S. Rasmussen +3 more
semanticscholar +1 more source
Bat-borne virus diversity, spillover and emergence
Nature Reviews Microbiology, 2020 Most viral pathogens in humans have animal origins and arose through cross-species transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus, Nipah virus, Hendra virus, severe acute respiratory syndrome coronavirus (SARS-
M. Letko +4 more
semanticscholar +1 more source
, 2021 Since the discovery of computers, bioinformatics and computational biology have been instrumental in a wide range of discoveries in virology. These include early mathematical models of virus-host interaction, and more recently the analysis of viral nucleotide and protein sequences to track their function, epidemiology, and evolution.
Pappas, Nikolaos +6 more
openaire +4 more sources
Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
J. R. Stat. Soc. C (2019), 2017 Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
Nature, 2016 The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number of cases and fatalities, geographic distribution, and number of nations affected, highlights the need for safe, effective, and readily available antiviral agents ...
Travis K Warren +61 more
semanticscholar +1 more source
SARS-CoV-2 Virus-Like Particles with Plasmonic Au Cores and S1-Spike Protein Coronas [PDF]
arXiv, 2022 The COVID-19 pandemic has stimulated the scientific world to intensify virus-related studies, aimed at the development of quick and safe ways of detecting viruses in human body, studying the virus-antibody and virus-cell interactions, and designing nanocarriers for targeted antiviral therapies.
arxiv
Complete Genome Sequence of Diaphorina citri-associated C virus, a Novel Putative RNA Virus of the Asian Citrus Psyllid, Diaphorina citri. [PDF]
, 2016 We present here the complete nucleotide sequence and genome organization of a novel putative RNA virus identified in field populations of the Asian citrus psyllid, Diaphorina citri, through sequencing of the transcriptome followed by reverse ...
Falk, Bryce W +2 more
core +1 more source
Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study [PDF]
, 2020 Background: Seasonal influenza virus is a common cause of acute lower respiratory infection (ALRI) in young children. In 2008, we estimated that 20 million influenza-virus-associated ALRI and 1 million influenza-virus-associated severe ALRI occurred in ...
Bassat Orellana, Quique +1 more
core +1 more source
mSphere, 2023 The primary route of Zika virus (ZIKV) transmission is through the bite of an infected Aedes mosquito, when it probes the skin of a vertebrate host during a blood meal.
Maria Vittoria Mancini +10 more
doaj +1 more source