Results 1 to 10 of about 5,647,758 (266)
Virus-host interaction networks as new antiviral drug targets for IAV and SARS-CoV-2 [PDF]
Emerging Microbes and Infections, 2022 Currently, SARS-CoV-2, especially the Omicron strain, is ravaging the world and even co-infecting human beings with IAV, which is a serious threat to human public health. As of yet, no specific antiviral drug has been discovered for SARS-CoV-2.
Na Chen +4 more
doaj +2 more sources
Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks. [PDF]
PLoS Computational BiologyViruses of microbes are ubiquitous biological entities that reprogram their hosts' metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental ...
G Eric Bastien +5 more
doaj +2 more sources
Role of Lipid Transfer Proteins (LTPs) in the Viral Life Cycle
Frontiers in Microbiology, 2021 Viruses are obligate parasites that depend on the host cell machinery for their replication and dissemination. Cellular lipids play a central role in multiple stages of the viral life cycle such as entry, replication, morphogenesis, and egress.
Kiran Avula +6 more
doaj +1 more source
Epstein–Barr virus–host cell interactions: an epigenetic dialog? [PDF]
Frontiers in Genetics, 2014 Epstein-Barr virus (EBV) is associated with diverse lymphoid and epithelial malignancies. Their molecular pathogenesis is accompanied by epigenetic alterations which are distinct for each of them. While lymphoblastoid cell lines (LCLs) derived from B cells transformed by EBV in vitro are characterized by a massive demethylation and euchromatinization ...
Niller, Hans H. +2 more
openaire +3 more sources
HIV-1 Natural Antisense Transcription and Its Role in Viral Persistence
Viruses, 2021 Natural antisense transcripts (NATs) represent a class of RNA molecules that are transcribed from the opposite strand of a protein-coding gene, and that have the ability to regulate the expression of their cognate protein-coding gene via multiple ...
Rui Li +3 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 The adult mammalian brain entails a reservoir of neural stem cells (NSCs) generating glial cells and neurons. However, NSCs become increasingly quiescent with age, which hampers their regenerative capacity. New means are therefore required to genetically
Lukas P.M. Kremer +12 more
doaj +1 more source
Genotype and phenotype of COVID-19: Their roles in pathogenesis
Journal of Microbiology, Immunology and Infection, 2021 COVID-19 is a novel coronavirus with an outbreak of unusual viral pneumonia in Wuhan, China, and then pandemic. Based on its phylogenetic relationships and genomic structures the COVID-19 belongs to genera Betacoronavirus.
Leila Mousavizadeh, Sorayya Ghasemi
doaj +1 more source
Special Issue: Host Cell–Virus Interaction
Viruses, 2022 As rightly put by Nobel Laureate Joshua Lederberg, “the single biggest threat to man’s continued dominance on the planet is the Virus” [...]
Anupam Mukherjee, Parikshit Bagchi
doaj +1 more source
The Landscape of Virus-Host Protein–Protein Interaction Databases
Frontiers in Microbiology, 2022 Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
doaj +1 more source
ITN—VIROINF: Understanding (Harmful) Virus-Host Interactions by Linking Virology and Bioinformatics
Viruses, 2021 Many recent studies highlight the fundamental importance of viruses. Besides their important role as human and animal pathogens, their beneficial, commensal or harmful functions are poorly understood.
Winfried Goettsch +17 more
doaj +1 more source