MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection [PDF]
Myxoma virus (MYXV), a member of the Poxviridae family, is the agent responsible for myxomatosis, a fatal disease in the European rabbit (Oryctolagus cuniculus).
Camus-Bouclainville, Christelle +11 more
core +1 more source
Virus latency: Heterogeneity of host-virus interaction in shaping the virosphere
Viruses and viroids that are not causing symptoms on their initial host plant are described by the terms “latent”, “cryptic” or “symptomless” and represent 6% and 2% of the classified plant viruses and viroids, respectively.
Richert-Pöggeler Katja R. +5 more
core +1 more source
Analysis of poxvirus host cell entry by electron microscopy [PDF]
Vaccinia virus (VACV) is the prototypic poxvirus and is complex in both composition and life cycle. In contrast to most viruses, poxviruses produce two types of infectious particles with different roles in virus dissemination: Mature virions (MVs ...
Bleck, Christopher Karl Ernst
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Comprehensive host-pathogen protein-protein interaction network analysis
Background Infectious diseases are a cruel assassin with millions of victims around the world each year. Understanding infectious mechanism of viruses is indispensable for their inhibition.
Babak Khorsand +2 more
doaj +1 more source
Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M. +34 more
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Mycophenolic acid (MPA) is an effective antiviral drug in plants, and its action in modulating the activity of KATP channels is already known in animals.
Andrea Luvisi +2 more
doaj +1 more source
Plus-stranded RNA viruses recruit cellular vesicles and co-opt cellular proteins involved in cellular metabolism and lipid biosynthesis to build viral replicase complexes (VRCs) within the large viral replication compartments. We use tombusviruses (TBSV),
Peter D. Nagy
doaj +1 more source
Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody [PDF]
<b>BACKGROUND:</b> In the acute phase of infection with feline immunodeficiency virus (FIV), the virus targets activated CD4+ T cells by utilising CD134 (OX40) as a primary attachment receptor and CXCR4 as a co-receptor.
Brian J Willett +11 more
core +1 more source
Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick +38 more
core +1 more source
Paradoxical Interplay of Viral and Cellular Functions
Some cellular editing functions can restrict the replication of some viruses but contribute to completion of the life cycle of others. A recent study has identified an isoform of the adenosine deaminase acting on RNA type 1 (ADAR 1) as required for ...
Esteban Domingo
doaj +1 more source

