Results 21 to 30 of about 5,926,013 (258)

Bioinformatics approaches for unveiling virus-host interactions

Computational and Structural Biotechnology Journal, 2023
The coronavirus disease-2019 (COVID-19) pandemic has elucidated major limitations in the capacity of medical and research institutions to appropriately manage emerging infectious diseases.
Hitoshi Iuchi, Junna Kawasaki, Kento Kubo, Tsukasa Fukunaga, Koki Hokao, Gentaro Yokoyama, Akiko Ichinose, Kanta Suga, Michiaki Hamada   +8 more
doaj   +1 more source

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. [PDF]

, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín, Landeras-Bueno, Sara, Jorba, N, Sara Landeras-Bueno, Ortín Juan, Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Núria Jorba, Landeras-Bueno Sara, Pérez-Cidoncha Maite, Landeras-Bueno, S, Ortín, J, Ortín, Juan, Jorba, Núria, Maite Pérez-Cidoncha, Jorba Núria   +15 more
core   +2 more sources

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm, Kathrin Hueging, Michael Ott, Hueging, Kathrin, Brohm, Christiane, Ott, Michael, Bitzegeio, Julia, Dorothea Bankwitz, Herrmann, Eva, Sibylle Haid, Thomas Pietschmann, Mirjam B. Zeisel, Baumert, Thomas F, Iken, Marcus, Haid, Sibylle, Marcus Iken, Julia Bitzegeio, Thomas F. Baumert, Zeisel, Mirjam B, Thomas F Baumert, Mirjam B Zeisel, Eva Herrmann, Baumert, Thomas, Bankwitz, Dorothea, Zeisel, Mirjam B., Pietschmann, Thomas   +25 more
core   +2 more sources

CPB1 of Aedes aegypti Interacts with DENV2 E Protein and Regulates Intracellular Viral Accumulation and Release from Midgut Cells

Viruses, 2014
Aedes aegypti is a principal vector responsible for the transmission of dengue viruses (DENV). To date, vector control remains the key option for dengue disease management.
Hong-Wai Tham, Vinod R. M. T. Balasubramaniam, Bimo Ario Tejo, Hamdan Ahmad, Sharifah Syed Hassan   +4 more
doaj   +1 more source

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]

, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy, Battegay, Manuel, E. Freitas, Jeffrey, G., James, Ian, Park, Lawrence P, Swiss HIV Cohort Study,, G. Jeffrey, Battegay, M., Jeffrey, Gary, Weber, R., Chapman, R., S. Herrmann, Furrer, Hansjakob, Telenti, Amalio, Telenti, A., Lucas, M., M. Lucas, null null, I. James, Weber, Rainer, Freitas, Elizabeth, H. Furrer, Gaudieri, S., S. A. Mallal, Park, P., Freitas, E., Cheng, W., K. Pfafferott, S. Gaudieri, R. Weber, Naidoo, Kiloshni, A. Rauch, Pfafferott, K., Mallal, Simon A, L. P. Park, Rauch, A., A. Telenti, Pfafferott, Katja, R. Chapman, Lucas, Michaela, M. Battegay, Park, L.P., Herrmann, Susan, K. Naidoo, Furrer, H., Rauch, Andri, W. Cheng, Herrmann, S., Naidoo, K., Chapman, Russell, Mallal, S.A., James, I., Gaudieri, Silvana, Park, Lawrence P., Mallal, S. A., Mallal, Simon A., Park, L. P.   +57 more
core   +1 more source

Receptors for Respiratory Syncytial Virus Infection and Host Factors Regulating the Life Cycle of Respiratory Syncytial Virus

Frontiers in Cellular and Infection Microbiology, 2022
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections and responsible for a large proportion of mortality in children and the elderly. There are no licensed vaccines available to date.
Ziheng Feng, Ziheng Feng, Lili Xu, Lili Xu, Zhengde Xie, Zhengde Xie   +5 more
doaj   +1 more source

Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1 [PDF]

, 2013
SAMHD1 is a host restriction factor that blocks the ability of lentiviruses such as HIV-1 to undergo reverse transcription in myeloid cells and resting T-cells. This restriction is alleviated by expression of the lentiviral accessory proteins Vpx and Vpr
Emerman, M, Chuanping Wang, Emerman, Michael, Jinwoo Ahn, Jennifer Mehrens (434943), Jacek Skowronski, Michael Emerman, Oliver I. Fregoso (434941), Wang, C, Jinwoo Ahn (140668), Ahn, Jinwoo, Oliver I Fregoso, Fregoso, Oliver I, Skowronski, Jacek, Skowronski, J, Ahn, J, Wang, Chuanping, Michael Emerman (12304), Fregoso, OI, Jennifer Mehrens, Mehrens, J, Mehrens, Jennifer, Chuanping Wang (434942), Jacek Skowronski (62180)   +23 more
core   +2 more sources

Data_Sheet_1_The Landscape of Virus-Host Protein–Protein Interaction Databases.zip

, 2022
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente (45897)
core   +1 more source

Cellular Lipids—Hijacked Victims of Viruses

Viruses, 2022
Over the millions of years-long co-evolution with their hosts, viruses have evolved plenty of mechanisms through which they are able to escape cellular anti-viral defenses and utilize cellular pathways and organelles for replication and production of ...
Bozena Omasta, Jana Tomaskova
doaj   +1 more source

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction [PDF]

, 2012
Genetic drift of influenza virus genomic sequences occurs through the combined effects of sequence alterations introduced by a low fidelity polymerase and the varying selective pressures experienced as the virus migrates through different host ...
García-Sastre, Adolfo, García-Sastre, A., Hunt, V., Squires, R Burke, Scheuermann, Richard H, Liu, Mengya, Galloway, S.E., Klem, Edward, Squires, R.B., Pickett, Brett E, Hale, B.G., Noronha, J.M., Takimoto, T., Hale, Benjamin G, Takimoto, Toru, Air, G.M., Schmolke, M., Klem, E., Liu, M., Hunt, Victoria, McGee, M., Pickett, B.E., Scheuerman, R.H., Noronha, Jyothi M, McGee, Monnie, Schmolke, Mirco, Air, Gillian M, Galloway, Summer E   +27 more
core   +1 more source