ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
Emerging translation strategies during virus-host interaction. [PDF]
Hoang HD, Neault S, Pelin A, Alain T.
europepmc +1 more source
Reassortment of NS Segments Modifies Highly Pathogenic Avian Influenza Virus Interaction with Avian Hosts and Host Cells [PDF]
Henning Petersen +4 more
openalex +1 more source
Senegalese sole (Solea senegalensis) ISG15: molecular characterization and in vivo interplay with viral infections [PDF]
The interferon-stimulated gene 15 (Isg15) is strongly induced by type I interferon (IFN I), viral infection, and double-stranded RNA (poly I:C) in several fish species, suggesting that Isg15 protein could play a key role in fish innate immunity against ...
Alonso-Sanchez, Maria del Carmen +5 more
core
TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu +9 more
wiley +1 more source
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing +10 more
wiley +1 more source
Editorial: Codon Usage and Dinucleotide Composition of Virus Genomes: From the Virus-Host Interaction to the Development of Vaccines. [PDF]
Pintó RM, Burns CC, Moratorio G.
europepmc +1 more source
Bovine virus diarrhea virus-host cell interaction
Ricardo F. Rosenbusch
openalex +2 more sources
Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source

