Results 101 to 110 of about 5,037,505 (267)

A single mutation in the PrM gene of Zika virus determines AXL dependency for infection of human neural cells

Journal of Virology
Zika virus (ZIKV) is spread by mosquito bites and is unique among known flaviviruses for being able to cause microcephaly. Entry factors for ZIKV are incompletely understood, but phosphatidylserine (PS) receptors, including the TAM (Tyro3, AXL, and Mer ...
Renu Khasa, Sarah C. Ogden, Yuqing Wang, Zongiun Mou, Anna D. Metzler, Xuping Xie, Xinghong Dai, Hengli Tang   +7 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Antibody‐Precomplexed Hemagglutinin Constructs Multivalently Bind Sialylated Glycan Receptors with Variable Valencies

Advanced Materials Interfaces, EarlyView.
Hemagglutinin precomplexation with antibodies (Abs) results in broad valency distributions, though it increases the total avidity from mM to nM to high nM. The valency distribution and the orientation of multivalent HA‐Ab complexes determine the extent of binding to different types of assays, whether the receptors are displayed in 2D or 3D.
Daniel Y. E. L. Tambuwun, María Ríos Carrasco, Elif Uslu, Geert‐Jan P. H. Boons, Nadia J. Mokiem, Albert J. R. Heck, Victor C. Yin, Robert P. de Vries, Jurriaan Huskens   +8 more
wiley   +1 more source

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +2 more sources

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Molecular and phylogenetic characterization of honey bee viruses, Nosema microsporidia, protozoan parasites, and parasitic mites in China [PDF]

, 2013
China has the largest number of managed honey bee colonies, which produce the highest quantity of honey and royal jelly in the world; however, the presence of honey bee pathogens and parasites has never been rigorously identified in Chinese apiaries.
Li, Tianbang, Bu Yang, Yang, Bu, Guangda Peng, Peng, Guangda, Kadowaki, Tatsuhiko, Tatsuhiko Kadowaki, Tianbang Li   +7 more
core   +1 more source

Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals

Non-Coding RNA, 2019
Exploring virus–host interactions is key to understand mechanisms regulating the viral replicative cycle and any pathological outcomes associated with infection.
Nkerorema Djodji Damas, Nicolas Fossat, Troels K. H. Scheel   +2 more
doaj   +1 more source

Hydro‐ and Lipophilicity of Molecular‐Size‐Controlled Hydrogel Drug Carriers

Advanced Materials Technologies, EarlyView.
We investigate nano‐sized hydrogel drug carriers with tailored hydro‐ and lipophilicity. We design their encapsulation and structure‐forming capabilities and follow them in real time during fabrication using time‐resolved and in situ grazing incidence x‐ray scattering.
Elisabeth Erbes, Naireeta Biswas, Calvin J. Gavillet, Matthias Schwartzkopf, Krishnayan Basuroy, Qing Chen, Andrei Chumakov, Susann Frenzke, Marc Gensch, Korneliya Gordeyeva, Patrycja Kielb, Sonja Kirchner, Volker Körstgens, Peter Müller‐Buschbaum, Henrike M. Müller‐Werkmeister, Jan Rubeck, Sreevidya Thekku Veedu, Jose de Jesus Velazquez‐Garcia, Vivian Waclawek, Daniel Söderberg, Stephan V. Roth, Simone Techert   +21 more
wiley   +1 more source

Virus–virus interactions and host ecology are associated with RNA virome structure in wild birds

, 2018
Virus–virus interactions and host ecology are associated with RNA virome structure in wild ...
Marcel Klaassen (13083138), M Wille (13347051), AC Hurt (10902642), EC Holmes (9634130), JS Eden (14466576), M Shi (12793552)   +5 more
core  

Research progress on miRNAs function in the interaction between human infectious viruses and hosts: A review

Biomolecules & Biomedicine
MicroRNAs (miRNAs) represent a class of non-coding small RNAs that are prevalent in eukaryotes, typically comprising approximately 22 nucleotides, and have the ability to post-transcriptionally regulate gene expression.
Xiaotong Wang, Wenchang Zhao
doaj   +1 more source