Results 161 to 170 of about 10,857,229 (262)

Complete recovery of thrombotic microangiopathy with severe acute kidney injury due to intravenous use of modified release oxycodone. [PDF]

Clin Kidney J
Ezeakile M, Zirapury T.
europepmc   +1 more source

Association of severe abnormal behavior of influenza patients and administered anti-influenza virus drugs: 2006-2022

International Journal of Infectious Diseases
Tamie Sugawara, Yasushi Ohkusa, Kiyosu Taniguchi, Chiaki Miyazaki, Yoko Kato, Nobuhiko Okabe   +5 more
openaire   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

Advanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina, Adam Tam, Jennifer Lam, Nila C. Wu, Nancy T. Li, Alison P. McGuigan   +5 more
wiley   +1 more source

Detection and characterization of antiviral-resistant viruses during the influenza season of 2024-25. [PDF]

Microbiol Spectr
Patel MC, Nguyen HT, Pascua PNQ, Lopez-Esteva M, Champion C, Mishin VP, Di H, Lacek K, Kirby MK, Bateman A, Sullivan M, Trow S, Laplante J, St George K, Rambo-Martin B, Merced-Morales A, Budd A, Kondor RJ, Davis CT, Gubareva LV.   +19 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Safety analysis of acyclovir use in neonates based on the FDA Adverse Event Reporting System: A retrospective observational pharmacovigilance study. [PDF]

Medicine (Baltimore)
He L, Wang B, Wang Y, Chen Y.
europepmc   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Risk Factors and Microbiological Characterization of Healthcare Associated Infection Post Cardiac Surgery Among Children in Beijing, China. [PDF]

Infect Drug Resist
Xu Y, Shen L, Ding N, Zhu Y, Chen Y, Zhao G, Li Z.   +6 more
europepmc   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

A 40-year-old man with a new diagnosis of hepatitis B. [PDF]

CMAJ
Biondi MJ, Parvez K, Redditt V, Feld JJ.
europepmc   +1 more source