Results 91 to 100 of about 6,133,142 (332)

Sand fly saliva reprograms skin fibroblasts to enhance arbovirus infection

iScience
Summary: Arbovirus transmission by sand flies is a growing public health concern, yet the early skin events shaping infection outcomes remain undefined.
Yonca Keskek Turk, Ailish McCafferty-Brown, Liam Barningham, Magdalena Jancarova, Petr Volf, Matthew E. Rogers, Akira J.T. Alexander, Çağdaş Kaya, Sandy MacDonald, Maria Grazia Cusi, Alain Kohl, Kave Shams, Clive S. McKimmie   +12 more
doaj   +1 more source

Virus–host interaction in feline immunodeficiency virus (FIV) infection

Comparative Immunology, Microbiology & Infectious Diseases, 2013
Feline immunodeficiency virus (FIV) infection has been the focus of several studies because this virus exhibits genetic and pathogenic characteristics that are similar to those of the human immunodeficiency virus (HIV).
S. Taniwaki, A. S. Figueiredo, J. Araújo   +2 more
semanticscholar   +1 more source

Influenza virus activation of the interferon system [PDF]

, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin, Killip, Marian J., Randall, RE, Fodor, E., Killip, MJ, Randall, Richard E., Fodor, E, Killip, M.J., Randall, R.E.   +8 more
core   +1 more source

A high-throughput yeast two-hybrid protocol to determine virus-host protein interactions

, 2022
S.1-15The yeast two-hybrid (Y2H) system is a powerful method to identify and analyze binary protein interactions. In the field of virology, the Y2H system has significantly increased our knowledge of structure and function of viral proteins by ...
Bailer, S., Koegl, M., Striebinger, H.
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection

mSystems, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-strand RNA virus. The viral genome is capped at the 5′ end, followed by an untranslated region (UTR). There is a poly(A) tail at the 3′ end, preceded by a UTR.
Rohit Verma, Sandhini Saha, Shiv Kumar, Shailendra Mani, Tushar Kanti Maiti, Milan Surjit   +5 more
doaj   +1 more source

Computational Analysis of HIV-1 Resistance Based on Gene Expression Profiles and the Virus-Host Interaction Network

PLoS ONE, 2011
A very small proportion of people remain negative for HIV infection after repeated HIV-1 viral exposure, which is called HIV-1 resistance. Understanding the mechanism of HIV-1 resistance is important for the development of HIV-1 vaccines and Acquired ...
Tao Huang, Zhongping Xu, Lei Chen, Yu-Dong Cai, Xiangyin Kong   +4 more
semanticscholar   +1 more source

Porcine Epidemic Diarrhea Virus: An Updated Overview of Virus Epidemiology, Virulence Variation Patterns and Virus–Host Interactions

Viruses, 2022
The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant morbidity and mortality, poses a huge threat to the swine industry.
Yuanzhu Zhang, Yiwu Chen, Jian Zhou, Xi Wang, Lerong Ma, Jianing Li, Lin Yang, Hong-Ming Yuan, D. Pang, H. Ouyang   +9 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Recognition of human oncogenic viruses by host pattern recognition receptors

Frontiers in Immunology, 2014
Human oncogenic viruses include Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1), Kaposi’s associated sarcoma virus (KSHV), and Merkel cell polyomavirus ...
Nelson C Di Paolo
doaj   +1 more source