Results 11 to 20 of about 6,133,142 (332)

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks. [PDF]

PLoS Computational Biology, 2023
Viruses of microbes are ubiquitous biological entities that reprogram their hosts' metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental ...
G Eric Bastien, Rachel N Cable, Cecelia Batterbee, A J Wing, Luis Zaman, Melissa B Duhaime   +5 more
doaj   +5 more sources

Bioinformatics approaches for unveiling virus-host interactions

Computational and Structural Biotechnology Journal, 2023
The coronavirus disease-2019 (COVID-19) pandemic has elucidated major limitations in the capacity of medical and research institutions to appropriately manage emerging infectious diseases.
Hitoshi Iuchi, Junna Kawasaki, Kento Kubo, Tsukasa Fukunaga, Koki Hokao, Gentaro Yokoyama, Akiko Ichinose, Kanta Suga, Michiaki Hamada   +8 more
doaj   +4 more sources

Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction. [PDF]

Nat Commun
The lack of a robust system to reproducibly propagate HRV-C, a family of viruses refractory to cultivation in standard cell lines, has substantially hindered our understanding of this common respiratory pathogen.
Li C, Yu Y, Wan Z, Chiu MC, Huang J, Zhang S, Zhu X, Lan Q, Deng Y, Zhou Y, Xue W, Yue M, Cai JP, Yip CC, Wong KK, Liu X, Yu Y, Huang L, Chu H, Chan JF, Clevers H, Yuen KY, Zhou J.   +22 more
europepmc   +2 more sources

RNA m⁶ A methylation regulates virus-host interaction and EBNA2 expression during Epstein-Barr virus infection. [PDF]

Immun Inflamm Dis, 2021
N6‐methyladenosine (m6A) is the most prevalent modification that occurs in messenger RNA (mRNA), affecting mRNA splicing, translation, and stability.
Zheng X, Wang J, Zhang X, Fu Y, Peng Q, Lu J, Wei L, Li Z, Liu C, Wu Y, Yan Q, Ma J.   +11 more
europepmc   +2 more sources

Defective viral genomes are key drivers of the virus-host interaction. [PDF]

Nat Microbiol, 2019
Viruses survive often harsh host environments, yet we know little about the strategies they utilize to adapt and subsist given their limited genomic resources. We are beginning to appreciate the surprising versatility of viral genomes and how replication-
Vignuzzi M, López CB.
europepmc   +2 more sources

COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms. [PDF]

Sci Data, 2020
Researchers around the world join forces to reconstruct the molecular processes of the virus-host interactions aiming to combat the cause of the ongoing pandemic.
Ostaszewski M, Mazein A, Gillespie ME, Kuperstein I, Niarakis A, Hermjakob H, Pico AR, Willighagen EL, Evelo CT, Hasenauer J, Schreiber F, Dräger A, Demir E, Wolkenhauer O, Furlong LI, Barillot E, Dopazo J, Orta-Resendiz A, Messina F, Valencia A, Funahashi A, Kitano H, Auffray C, Balling R, Schneider R.   +24 more
europepmc   +2 more sources

The Landscape of Virus-Host Protein–Protein Interaction Databases

Frontiers in Microbiology, 2022
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
doaj   +3 more sources

Network-based Virus-Host Interaction Prediction with Application to SARS-CoV-2

bioRxiv, 2020
COVID-19, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has quickly become a global health crisis since the first report of infection in December of 2019.
Du H, Chen F, Liu H, Hong P.
europepmc   +2 more sources

Host restriction factors in retroviral infection: promises in virus-host interaction

Retrovirology, 2012
Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-host interactions. Among retroviruses, the primate lentiviruses have one of the more complex genome structures with three categories of viral genes ...
Zheng Yong-Hui, Jeang Kuan-Teh, Tokunaga Kenzo   +2 more
doaj   +2 more sources

Virogenomics: the virus–host interaction revisited

Current Opinion in Microbiology, 2008
Genomics tools allow us to assess gene expression ‘genome wide’ providing an unprecedented view on the host-side of the virus–host interaction. The success of the application of these tools crucially depends on our ability to reduce the total information
A. Andeweg, B. Haagmans, A. Osterhaus
semanticscholar   +3 more sources