Results 41 to 50 of about 5,926,015 (303)

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain [PDF]

, 2011
Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization may autoregulate its actions.
Margaret A Taylor, Richard E. Randall, García-Sastre, A., Hale Benjamin G., Kerry, P.S., Lewis Andrew, Taylor Margaret A., Kerry, Philip S., Andrew Lewis, Kerry Philip S., Hass, C., Benjamin G. Hale, Hale, Benjamin G., Rupert J. Russell, Juan Ayllon, Richard E Randall, Randall Richard E., Hale, B.G., Margaret A. Taylor, Ayllon, Juan, Philip S Kerry, Randall, R.E., Adolfo García-Sastre, Ayllón Barasoain, Juan, Lewis, Andrew, Hass Claudia, Ayllon, J., Rupert J Russell, García Sastre, Adolfo, Taylor, M.A., Lewis, A., García-Sastre Adolfo, Taylor, Margaret A., Hass, Claudia, Ayllon Juan, Russell, R.J., Randall, Richard E., Claudia Hass, Russell, Rupert J., Benjamin G Hale, Russell Rupert J., Philip S. Kerry, Garcia-Sastre, Adolfo, Randall, Richard E.; id_orcid   +43 more
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AAV vector-mediated in vivo reprogramming into pluripotency

Nature Communications, 2018
In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.
Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano, Dirk Grimm   +12 more
doaj   +1 more source

Pathogenesis of influenza: virus–host interactions

Expert Review of Anti-infective Therapy, 2011
Since their inception in March 1972, Keystone Symposia on Molecular and Cellular Biology have brought together scientists from across the globe to discuss key biological topics. Now in its 40th year, it is a completely independent, nonprofit organization devoted solely to providing outstanding scientific conferences in all areas of the biological and ...
Godlee, A, Almond, M, Dong, T
openaire   +3 more sources

Diagrammatic representation of host-virus interaction, cell entry, replication, budding and release of the newly formed virus.

, 2021
Diagrammatic representation of host-virus interaction, cell entry, replication, budding and release of the newly formed virus.
Farah Anjum (10425505), Md. Imtaiyaz Hassan (355009), Sufian Badar (11846545), Abdelbaset Mohamed Elasbali (11638732), Dharmendra Kumar Yadav (4995386), Alaa Shafie (10047630), Ahmad Abu Turab Naqvi (726966)   +6 more
core   +1 more source

Comprehensive host-pathogen protein-protein interaction network analysis

BMC Bioinformatics, 2020
Background Infectious diseases are a cruel assassin with millions of victims around the world each year. Understanding infectious mechanism of viruses is indispensable for their inhibition.
Babak Khorsand, Abdorreza Savadi, Mahmoud Naghibzadeh   +2 more
doaj   +1 more source

Effects of extracellular K+ on grapevine membrane potential as influenced by the antiviral mycophenolic acid. An electrophysiological study

Advances in Horticultural Science, 2015
Mycophenolic acid (MPA) is an effective antiviral drug in plants, and its action in modulating the activity of KATP channels is already known in animals.
Andrea Luvisi, Enrico Rinaldelli, A. Panattoni   +2 more
doaj   +1 more source

Exploitation of Host Factors and Cellular Pathways by Tombusviruses for the Biogenesis of the Viral Replication Organelles

Proceedings, 2020
Plus-stranded RNA viruses recruit cellular vesicles and co-opt cellular proteins involved in cellular metabolism and lipid biosynthesis to build viral replicase complexes (VRCs) within the large viral replication compartments. We use tombusviruses (TBSV),
Peter D. Nagy
doaj   +1 more source

Targeting Virus-host Interactions of HIV Replication

Current Topics in Medicinal Chemistry, 2015
Cellular proteins that are hijacked by HIV in order to complete its replication cycle, form attractive new targets for antiretroviral therapy. In particular, the protein-protein interactions between these cellular proteins (cofactors) and viral proteins are of great interest to develop new therapies.
Weydert, Caroline, De Rijck, Jan, Christ, Frauke, Debyser, Zeger   +3 more
openaire   +2 more sources

Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag?TSG101 interaction

, 2008
The egress of HIV particles from virus-infected cells is accomplished by the recruitment of proteins that normally mediate host cell endocytic functions.
Gam, Jongsik, Cohen, Stanley N., Benkovic, Stephen J., Pans, Hui, Tavassoli, Ali, Lu, Quan   +5 more
core   +1 more source

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]

, 2010
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick, Doffoel, Michel, Leroux-Roels, G., Stoll-Keller, Françoise, Michel Doffoël, Patel, Arvind H, Samira Fafi-Kremer, Fofana, I., Soulier, E., Patric Carolla, Fafi-Kremer, S., Doffoel, M., Stoll-Keller, F., Cosset, F.-L., Meuleman, Philip, Fafi-Kremer, Samira, Eric Soulier, Philip Meuleman, Isabel Fofana, Wolf, P., Soulier, Eric, Cosset, François-Loic, François-Loïc Cosset, Leroux-Roels, Geert, Wolf, Philippe, Françoise Stoll-Keller, Philippe Wolf, Carolla, Patric, Pessaux, P., Meuleman, P., Baumert, Thomas F, Patel, A.H., Fofana, Isabel, Patrick Pessaux, Thomas F. Baumert, Arvind H. Patel, Geert Leroux-Roels, Carolla, P., Baumert, T.F.   +38 more
core   +1 more source