Results 21 to 30 of about 253,995 (253)

Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins

open access: yeseLife, 2014
A 3.3 MDa macromolecular cage between two Escherichia coli proteins with seemingly incompatible symmetries–the hexameric AAA+ ATPase RavA and the decameric inducible lysine decarboxylase LdcI–is reconstructed by cryo-electron microscopy to 11 Å ...
Hélène Malet   +7 more
doaj   +1 more source

Viruses of Microbes 2020: The Latest Conquest on Viruses of Microbes

open access: yesViruses, 2021
This Special Issue celebrates viruses of microbes: those viruses that infect archaea, bacteria and microbial eukaryotes [...]
Tessa E. F. Quax   +2 more
doaj   +1 more source

Spatial Transcriptomics to Study Virus-Host Interactions. [PDF]

open access: yesAnnu Rev Virol
The morbidity and mortality associated with viral diseases in plants, animals, and humans are significant concerns. Understanding how viruses cause disease and identifying the viral and host factors that determine the outcome of infection are essential to develop new antiviral therapeutics and strategies to induce protective immunity.
Holdener C   +6 more
europepmc   +3 more sources

Virus-Host Interactions [PDF]

open access: yesCell, 2011
Viruses display remarkable specificity in both the host species and the cell types that they infect. Understanding this specificity reveals insight into the basic host components that are required for the viral life cycle and host restriction factors that limit the virus.
openaire   +1 more source

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks. [PDF]

open access: yesPLoS Comput Biol, 2023
Viruses of microbes are ubiquitous biological entities that reprogram their hosts’ metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental health.
Bastien GE   +5 more
europepmc   +3 more sources

The Landscape of Virus-Host Protein–Protein Interaction Databases

open access: yesFrontiers in Microbiology, 2022
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
doaj   +1 more source

Structure-based mechanism of action of a viral poly(ADP-ribose) polymerase 1-interacting protein facilitating virus replication

open access: yesIUCrJ, 2018
Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that modifies nuclear proteins by poly(ADP-ribosyl)ation, regulates various cellular activities and restricts the lytic replication of oncogenic gammaherpesviruses by inhibiting the function of ...
Woo-Chang Chung   +7 more
doaj   +1 more source

Virus–Host Interactions in Foot-and-Mouth Disease Virus Infection

open access: yesFrontiers in Immunology, 2021
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which has been regarded as a persistent challenge for the livestock industry in many countries. Foot-and-mouth disease virus (FMDV) is the etiological agent of FMD that
Kangli Li   +5 more
doaj   +1 more source

Pathogenesis of influenza: virus–host interactions

open access: yesExpert Review of Anti-infective Therapy, 2011
Since their inception in March 1972, Keystone Symposia on Molecular and Cellular Biology have brought together scientists from across the globe to discuss key biological topics. Now in its 40th year, it is a completely independent, nonprofit organization devoted solely to providing outstanding scientific conferences in all areas of the biological and ...
Godlee, A, Almond, M, Dong, T
openaire   +3 more sources

Limited impact of hepatitis A virus 3C protease-mediated cleavage on the functions of NEMO in human hepatocytes

open access: yesJournal of Virology
NF-κB essential modulator (NEMO) is critically involved in the induction of interferons (IFNs) and pro-inflammatory cytokines. Hepatitis A virus (HAV) 3C protease was recently identified to cleave NEMO in non-hepatic cells.
Hao-En Huang   +3 more
doaj   +1 more source

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