Results 41 to 50 of about 5,037,554 (304)

Virus–Host Interactions in Foot-and-Mouth Disease Virus Infection

Frontiers in Immunology, 2021
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which has been regarded as a persistent challenge for the livestock industry in many countries. Foot-and-mouth disease virus (FMDV) is the etiological agent of FMD that
Kangli Li, Congcong Wang, Fan Yang, Weijun Cao, Zixiang Zhu, Haixue Zheng   +5 more
doaj   +1 more source

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks. [PDF]

PLoS Comput Biol, 2023
Viruses of microbes are ubiquitous biological entities that reprogram their hosts’ metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental health.
Bastien GE, Cable RN, Batterbee C, Wing AJ, Zaman L, Duhaime MB.   +5 more
europepmc   +4 more sources

Targeting Virus-host Interactions of HIV Replication

Current Topics in Medicinal Chemistry, 2015
Cellular proteins that are hijacked by HIV in order to complete its replication cycle, form attractive new targets for antiretroviral therapy. In particular, the protein-protein interactions between these cellular proteins (cofactors) and viral proteins are of great interest to develop new therapies.
Weydert, Caroline, De Rijck, Jan, Christ, Frauke, Debyser, Zeger   +3 more
openaire   +2 more sources

Protein–Protein Interactions in Virus–Host Systems [PDF]

Frontiers in Microbiology, 2017
To study virus-host protein interactions, knowledge about viral and host protein architectures and repertoires, their particular evolutionary mechanisms, and information on relevant sources of biological data is essential. The purpose of this review article is to provide a thorough overview about these aspects.
Brito, AF, Pinney, JW
openaire   +4 more sources

Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data

eLife, 2021
Background: Rapid identification and investigation of healthcare-associated infections (HCAIs) is important for suppression of SARS-CoV-2, but the infection source for hospital onset COVID-19 infections (HOCIs) cannot always be readily identified based ...
Oliver Stirrup, Joseph Hughes, Matthew Parker, David G Partridge, James G Shepherd, James Blackstone, Francesc Coll, Alexander Keeley, Benjamin B Lindsey, Aleksandra Marek, Christine Peters, Joshua B Singer, The COVID-19 Genomics UK (COG-UK) consortium, Asif Tamuri, Thushan I de Silva, Emma C Thomson, Judith Breuer   +16 more
doaj   +1 more source

Protein-protein interactions leading to recruitment of the host DNA sliding clamp by the hyperthermophilic Sulfolobus islandicus rod- shaped virus 2 [PDF]

, 2014
Viruses infecting hyperthermophilic archaea typically do not encode DNA polymerases, raising questions regarding their genome replication. Here, using a yeast two-hybrid approach, we have assessed interactions between proteins of Sulfolobus islandicus ...
Gardner, A.F., Bell, S.D., Krupovic, M., Prangishvili, D., White, M.F.   +4 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Functional Landscape of African Swine Fever Virus–Host and Virus–Virus Protein Interactions

Viruses, 2023
Viral replication fully relies on the host cell machinery, and physical interactions between viral and host proteins mediate key steps of the viral life cycle.
Katarzyna Magdalena Dolata, Gang Pei, Christopher L. Netherton, Axel Karger   +3 more
doaj   +1 more source

Influenza virus activation of the interferon system [PDF]

, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin, Killip, Marian J., Randall, RE, Fodor, E., Killip, MJ, Randall, Richard E., Fodor, E, Killip, M.J., Randall, R.E.   +8 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source