Results 61 to 70 of about 5,037,554 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Identification of a culturable fungal species and endosymbiotic bacteria in saliva of Aedes aegypti and Culex pipiens and their impact on arbovirus infection in vitro

Parasites & Vectors
Background Mosquito saliva plays a key role in arbovirus transmission and pathogenesis. It was shown that saliva contains several molecules that are essential for blood feeding.
Lanjiao Wang, Laure Remue, Nikki Adriaens, Alina Soto, Sam Verwimp, Joyce van Bree, Katrien Trappeniers, Leen Delang   +7 more
doaj   +1 more source

Heterogeneous host susceptibility enhances prevalence of mixed-genotype micro-parasite infections [PDF]

, 2011
Dose response in micro-parasite infections is usually shallower than predicted by the independent action model, which assumes that each infectious unit has a probability of infection that is independent of the presence of other infectious units. Moreover,
Zwart, Mark P., Lia Hemerik, Hemerik, L., Just M. Vlak, Mark P. Zwart, Mark P Zwart, Vlak, J.M., van der Werf, Wopke, van der Werf Wopke, Hemerik, Lia, Just M Vlak, Hemerik Lia, Vlak Just M., Zwart Mark P., Zwart, M.P., Wopke van der Werf, Vlak, Just M., Werf, W., van der, van der Werf, W.   +18 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions [PDF]

, 2011
Background Infection processes consist of a sequence of steps, each critical for the interaction between host and parasite. Studies of host-parasite interactions rarely take into account the fact that different steps might be influenced by different ...
Ebert, Dieter, Dieter Ebert, Ben-Ami, Frida, Laforsch Christian, Duneau David, Ebert Dieter, David Duneau, Laforsch, C., Luijckx Pepijn, Duneau, David, Luijckx, P., Ben-Ami, F., Luijckx, Pepijn, Frida Ben-Ami, Pepijn Luijckx, Duneau, D., Ben-Ami Frida, Christian Laforsch, Laforsch, Christian   +18 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Early Virus–Host Cell Interactions

Journal of Molecular Biology, 2018
International ...
openaire   +4 more sources

Is Culex modestus a New Usutu virus vector?

Parasites & Vectors
Usutu virus is an emerging pathogen transmitted by mosquitoes. Culex modestus mosquitoes are widespread in Europe, but their role in disease transmission is poorly understood.
Alina Soto, Lotte Wauters, Leen Delang
doaj   +1 more source

Defense pathways in Arabidopsis restricting compatible tobamoviruses during infection [PDF]

, 2014
Virus infected plants often develop strong disease symptoms including leaf deformation, chlorosis, necrosis and growth inhibition. In agriculture systems virus infection can lead to severe yield losses and a better understanding of plant defenses against
Kørner, Camilla Julie
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source