Results 51 to 60 of about 5,037,554 (304)

Initial lentivirus-host interactions within lymph nodes: a study of maedi-visna virus infection in sheep [PDF]

, 1995
Reactive changes occurring within lymph nodes draining the subcutaneous site of acute infection with maedi-visna virus (MVV) were studied, and the appearance of infected cells correlated with the immune response.
Hopkins, John, MacLennan, I C, McConnell, I., Allen, D., Roy, D J, Sargan, D R, Blacklaws, Barbara A., Bird, P   +7 more
core  

The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]

, 2014
Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, N J, Simmonds, Peter, Atkinson, Nicky J., Evans, David J., Witteveldt, Jeroen, Evans, D. J.   +5 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells

Journal of Virology
Abundance of essential components of double-stranded RNA (dsRNA) recognition and the subsequent interferon (IFN) response vary widely between primary human hepatocytes (PHHs) and commonly used cell culture models based on derivatives of Huh7 cells ...
Andreas Betz, Hao-En Huang, Zuguang Gu, Ombretta Colasanti, Teng-Feng Li, Jasper Hesebeck-Brinckmann, Nadine Gillich, Gnimah Eva Gnouamozi, Matthias Schlesner, Florian W. R. Vondran, Stephan Urban, Ralf Bartenschlager, Marco Binder, Volker Lohmann   +13 more
doaj   +1 more source

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

EMBO Molecular Medicine, 2017
Toxoplasma gondii is an important food and waterborne pathogen causing toxoplasmosis, a potentially severe disease in immunocompromised or congenitally infected humans.
Andrés Palencia, Alexandre Bougdour, Marie‐Pierre Brenier‐Pinchart, Bastien Touquet, Rose‐Laurence Bertini, Cristina Sensi, Gabrielle Gay, Julien Vollaire, Véronique Josserand, Eric Easom, Yvonne R Freund, Hervé Pelloux, Philip J Rosenthal, Stephen Cusack, Mohamed‐Ali Hakimi   +14 more
doaj   +1 more source

Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function

Cell Reports, 2016
Sister chromatid cohesion is a fundamental prerequisite to faithful genome segregation. Cohesion is precisely regulated by accessory factors that modulate the stability with which the cohesin complex embraces chromosomes.
Kyle W. Muir, Marc Kschonsak, Yan Li, Jutta Metz, Christian H. Haering, Daniel Panne   +5 more
doaj   +1 more source

The influence of viral RNA secondary structure on interactions with innate host cell defences [PDF]

, 2013
RNA viruses infecting vertebrates differ fundamentally in their ability to establish persistent infections with markedly different patterns of transmission, disease mechanisms and evolutionary relationships with their hosts.
Blundell, Richard, Richard Blundell, Nora McFadden, Joris J. Maarleveld, Maarleveld, Joris J, Evans, David J, Simmonds, Peter, Jeroen Witteveldt, Maarleveld, Joris J., David J. Evans, McFadden, Nora, Peter Simmonds, Evans, David J., Witteveldt, Jeroen   +13 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Poxvirus Proteomics and Virus-Host Protein Interactions [PDF]

Microbiology and Molecular Biology Reviews, 2009
SUMMARY Studies of the functional proteins encoded by the poxvirus genome provide information about the composition of the virus as well as individual virus-virus protein and virus-host protein interactions, which provides insight into viral pathogenesis and drug discovery.
Kim, Van Vliet, Mohamed R, Mohamed, Leiliang, Zhang, Nancy Yaneth, Villa, Steven J, Werden, Jia, Liu, Grant, McFadden   +6 more
openaire   +2 more sources

A virulent strain of deformed wing virus (DWV) of honeybees (Apis mellifera) prevails after varroa destructor-mediated, or in vitro, transmission [PDF]

, 2014
The globally distributed ectoparasite Varroa destructor is a vector for viral pathogens of the Western honeybee (Apis mellifera), in particular the Iflavirus Deformed Wing Virus (DWV).
James C Bull, Jonathan D. Moore (262014), Fannon, Jessica, Jonathan D. Moore, Dave Ch, Graham R Wood, James C. Bull¤a, Fannon, Jessica M., Jessica M Fannon, Mead, Andrew, Jessica M. Fannon (589359), James C. Bull (107677), Nigel Burroughs (589360), David J. Evans (208308), Graham R. Wood, Nigel Burroughs, David J. Evans, Ryabov, Eugene V., Wood, Graham R., Chandler, Dave, Eugene V. Ryabov (107680), Mead, A. (Andrew), Eugene V Ryabov, Andrew Mead, David J Evans, Jonathan D Moore, Moore, Jonathan D., Wood, Graham, Bull, James C., Burroughs, Nigel, Graham R. Wood (589358), Dave Chandler (107700), Dave Chandler, Jessica M. Fannon, Andrew Mead (107686), Bull, James C. (James Christopher), Burroughs, Nigel John, Evans, David J., Eugene V. Ryabov   +38 more
core   +2 more sources