Results 81 to 90 of about 487,341 (302)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Analyzing plant stress granules in response to plant viruses [PDF]

, 2018
Plant viruses have the ability to redirect host machineries and processes to establish a productive infection. Virus-host interactions lead to the reprogramming of the plant cell cycle and transcriptional controls, inhibition of cell death pathways ...
Krenz, Björn
core  

Autoimmune neurological conditions associated with Zika virus infection [PDF]

, 2018
Zika virus (ZIKV) is an emerging flavivirus rapidly spreading throughout the tropical Americas. mosquitoes is the principal way of transmission of the virus to humans. ZIKV can be spread by transplacental, perinatal, and body fluids.
Acosta-Ampudia, Yeny, Anaya, Juan-Manuel, Castillo-Medina, Luis F, Halstead, Susan, Monsalve, Diana M, Pacheco, Yovana, Ramírez-Santana, Carolina, Rodríguez, Yhojan, Willison, Hugh J.   +8 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response

Frontiers in Immunology
Background and aimsThe contribution of innate immunity to clearance of viral infections of the liver, in particular sensing via Toll-like receptor 3 (TLR3), is incompletely understood. We aimed to identify the factors contributing to the TLR3 response in
Teng-Feng Li, Paul Rothhaar, Arthur Lang, Oliver Grünvogel, Ombretta Colasanti, Santa Mariela Olivera Ugarte, Jannik Traut, Antonio Piras, Nelson Acosta-Rivero, Vladimir Gonçalves Magalhães, Emely Springer, Andreas Betz, Hao-En Huang, Jeongbin Park, Jeongbin Park, Jeongbin Park, Ruiyue Qiu, Gnimah Eva Gnouamozi, Ann-Kathrin Mehnert, Viet Loan Dao Thi, Viet Loan Dao Thi, Stephan Urban, Stephan Urban, Martina Muckenthaler, Matthias Schlesner, Matthias Schlesner, Dirk Wohlleber, Marco Binder, Ralf Bartenschlager, Ralf Bartenschlager, Ralf Bartenschlager, Andreas Pichlmair, Andreas Pichlmair, Volker Lohmann, Volker Lohmann   +34 more
doaj   +1 more source

Virus-host protein interactions in RNA viruses [PDF]

Microbes and Infection, 2010
RNA viruses exhibit small-sized genomes that only encode a limited number of viral proteins, but still establish complex networks of interactions with host cell components. Here we summarize recent reports that aim at understanding general features of RNA virus infection networks at the protein level.
Vidalain, Pierre-Olivier, Tangy, Frédéric   +1 more
openaire   +2 more sources

Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the host translation machinery. [PDF]

, 2013
The 3' untranslated region (3'UTR) of hepatitis C virus (HCV) messenger RNA stimulates viral translation by an undetermined mechanism. We identified a high affinity interaction, conserved among different HCV genotypes, between the HCV 3'UTR and the host ...
Bai, Yun, Doudna, Jennifer A, Zhou, Kaihong   +2 more
core   +2 more sources

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow, Nicola McKern, Vincent Oxenham, Kate Ahmad, Omar Ahmad   +4 more
wiley   +1 more source

Structural characterization of antibiotic self-immunity tRNA synthetase in plant tumour biocontrol agent

Nature Communications, 2016
The bacterium Agrobacterium radiobacter K84 secretes an antibiotic that is transported into the plant pathogen A. tumefaciensand processed into the toxin TM84.
Shaileja Chopra, Andrés Palencia, Cornelia Virus, Sarah Schulwitz, Brenda R. Temple, Stephen Cusack, John Reader   +6 more
doaj   +1 more source

Tobacco mosaic virus Induced Alterations in the Gene Expression Profile of Arabidopsis thaliana

Molecular Plant-Microbe Interactions, 2003
In this study, mRNA profiles generated from cDNA microarrays were used to identify gene expression changes in Arabidopsis thaliana ecotype Shahdara infected with Tobacco mosaic virus (TMV).
Sheetal Golem, James N. Culver
doaj   +1 more source